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Doctor insights on: Creatinine Clearance Vs Gfr

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Dr. Suzanne Galli
39 doctors shared insights

Creatinine Clearance (Definition)

Creatinine clearance is used in clinical practice to give an estimate of overall kidney function, or glomerular filtration rate. Generally normal is considered 100 or above, but it goes down every year and elderly patients may have low clearance ...Read more


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What is a creatinine clearance rate and GFR?

CrCl & GFR: GFR stands for Glomerular Filtration Rate which is a measure of the filtering function of your kidneys. Creatinine Clearance is one of the methods used to measure a person's GFR and it is often done by measuring the amount of creatinine in a 24 hr urine collection or can be estimated by using an equation called "Cockcroft-Gault" formula. ...Read more

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Are creatinine clearance and GFR the same thing?

Sort of: The true glomerular filtration rate is very hard to measure. The creatinine clearance is a practical way of measuring it, which requires a timed urine collection and a blood sample. It is much more accurate then the crude and subscientific estimate of the glomerular filtration rate / GFR from a spot creatinine. ...Read more

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What comparison or correlation can be made between the creatinine clearance test and GFR?

What comparison or correlation can be made between the creatinine clearance test and GFR?

Estimate: The true creatinine clearance test, which requires a timed urine, is much more accurate as a measure of glomerular filtration rate than is the crude and subscientific estimate obtained from just a spot serum creatinine. ...Read more

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Is there a relationship between creatinine clearance and GFR?

Yes: True glomerular filtration rate is very hard to determine, but it can be estimated crudely using the creatinine clearance, which looks at serum and urine creatinine concentrations in a timed and volume-measured urine. This in turn is far more accurate than the subscientific estimate of GFR that's often part of a lab panel. ...Read more

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Trace amounts of glucose in urine. Blood glucose 94 and A1C was like 5. Creatinine clearance levels 0.9. BUN levels 20. GFR 77.5. 45 y/o wf.

Trace amounts of glucose in urine. Blood glucose 94 and  A1C was like 5.  Creatinine clearance levels 0.9.  BUN levels 20.  GFR 77.5.  45 y/o wf.

Fasting: Would recommend a repeat morning urine analysis in 1-2 weeks. I suspect a falsely positive, but in the presence of high suspicion for diabetes, family history, overweight, symptoms, etc follow up would be recommended. ...Read more

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My lab reports are serum creatinine 80, GFR 72, and creatinine clearance 69.9. my 24 hr urine creatinine was 6.9 and spot urine 2.2. What does it mean?

Not much: You're 55 years old and -- congratulations -- a recovered problem drinker. Unless you're especially fit or heavily-muscled, your creatinine may be a bit high and maybe your kidneys are getting old -- but this level is perfectly compatible with good health and if you had serious kidney disease, it would be a lot worse by now. Eat sensibly, stay fit and I bet your kidneys will last a lifetime. ...Read more

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Creatinine clearance? What for?

Kidney function: Creatinine clearance is a calculation that serves as a measure of kidney function. There are 5 stages of kidney disease before end-stage. The stage guides treatment and allows the doctor to monitor changes over time. ...Read more

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Creatinine clearance --what exactly is it?

It is a measure: Of creatinine, a breakdown product of muscle, and the efficiency of it's removal by functioning kidneys. It is measured by a blood testof creatinine, and a 24 hour urine collection to assess how much is cleared per hour. It is the gold standard of kidney function. ...Read more

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Is it ok to have creatinine clearance of 42 at 92 ?

Is it ok to have creatinine clearance of 42 at 92 ?

Almost normal: It is normal to lose some filtering units with age so that after age 40 the creatinine clearance starts to fall. This will be accelerated by hypertension or obesity or diabetes but even in normal individuals it falls at a lower rate. At age 90 a creatinine clearance of about 60 mls per min would be expected so 42 is close to it. ...Read more

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Dr. Madhu Kandarpa
2,189 doctors shared insights

Creatinine (Definition)

Creatinine is a byproduct of creatine phosphate, which is present in muscles. Creatinine levels increase if the ...Read more