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Doctor insights on: Creatinine Clearance Test Preparation

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Dr. Cornelius O'Leary Jr
39 doctors shared insights

Creatinine Clearance (Definition)

Creatinine clearance is used in clinical practice to give an estimate of overall kidney function, or glomerular filtration rate. Generally normal is considered 100 or above, but it goes down every year and elderly patients may have low clearance ...Read more


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Doing creatinine clearance test is pain in the a#@?

Doing creatinine clearance test is pain in the a#@?

Peeing in a bottle:): Creatinine clearance is an exact measurement of renal function, much more accurate than calculation made from serum creatinine alone. The 'pain' i guess you are referring to is that to do the test accurately requires collecting every drop of urine in a special bottle given by the lab for 24 hours. Enjoy the challenge-:). ...Read more

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My creatinine clearance test came back low. What does this mean?

My creatinine clearance test came back low. What does this mean?

Creatinine clearance: Low creatinine clearance means your kidney is not filtering normal amount of creatinine in the urine because of some disease process. ...Read more

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What comparison or correlation can be made between the creatinine clearance test and GFR?

Estimate: The true creatinine clearance test, which requires a timed urine, is much more accurate as a measure of glomerular filtration rate than is the crude and subscientific estimate obtained from just a spot serum creatinine. ...Read more

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Why are a creatinine clearance test and a serum creatinine test done together?

To get proper result: Creatinine clearance testing procedure and what measured is fully answered in prior question. The serum creatinine must be drawn right after the 24 hour urine collection to calculate how much creatinine is in serum and compare it to the total creatinine in the urine collection, to get an accurate measurement of renal function. ...Read more

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Why would the creatinine clearance test not be useful for detecting early renal disease?

Urine collection: Creatinine clearance requieres a full and precise 24 hour urine collection. The results can be falsely low if there is an undercollection, or falsely high if there is an overcollection. Also, creatinine can be affected by a high protein diet (the "ghoulash effect"). Such diets will raise serum creatinine. ...Read more

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I'm wondering why are both a creatinine clearance test and a serum creatinine test done?

Creatinine clearance: People who want to find out their renal function will collect a 24 hour urine for creatinine clearance. The blood sample is used to calculate the clearance of creatinine in the urine as it will be sent off for a creatinine level. Without it, the clearance of creatinine could not be calculated. The result of the test give the actual glomerular filtration rate of the patient. ...Read more

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Why are both a creatinine clearance test and a serum creatinine test done? Pain in the rear to collect.

See below: You are right, a collection of the 24 hour urine is cumbersome.It is possible to have a estimate of the GFR and creatinine clearance based on serum creatinine with a formula and tables which are easily available, which dose not require the urine collection. The 24 hour collection may be more accurate in extremes of weight etc and not necessary for most clinical scenarios. ...Read more

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Blood test: estimated creatinine clearance test (low), what could it indicate? EGFR & creatinine normal. Potassium & sodium low. 28yr/f

How do you FEEL?: Many (maybe most) pathologists and nephrologists aren't impressed with the current practice of labs estimate GFR, creatinine clearance and so forth from a spot creatinine. Some formulas include race "because black people are more muscular than white people" -- these were never intended to be applied to individuals. Frankly, if your others labs are healthy, I'd ignore it. ...Read more

Dr. Madhu Kandarpa
2,189 doctors shared insights

Creatinine (Definition)

Creatinine is a byproduct of creatine phosphate, which is present in muscles. Creatinine levels increase if the ...Read more