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Doctor insights on: Creatinine Clearance Test Preparation

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Dr. Peter Ihle
39 doctors shared insights

Creatinine Clearance (Definition)

Creatinine clearance is used in clinical practice to give an estimate of overall kidney function, or glomerular filtration rate. Generally normal is considered 100 or above, but it goes down every year and elderly patients may have low clearance ...Read more


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Doing creatinine clearance test is pain in the a#@?

Doing creatinine clearance test is pain in the a#@?

Peeing in a bottle:): Creatinine clearance is an exact measurement of renal function, much more accurate than calculation made from serum creatinine alone. The 'pain' i guess you are referring to is that to do the test accurately requires collecting every drop of urine in a special bottle given by the lab for 24 hours. Enjoy the challenge-:). ...Read more

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My creatinine clearance test came back low. What does this mean?

My creatinine clearance test came back low. What does this mean?

Creatinine clearance: Low creatinine clearance means your kidney is not filtering normal amount of creatinine in the urine because of some disease process. ...Read more

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What comparison or correlation can be made between the creatinine clearance test and GFR?

Estimate: The true creatinine clearance test, which requires a timed urine, is much more accurate as a measure of glomerular filtration rate than is the crude and subscientific estimate obtained from just a spot serum creatinine. ...Read more

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Why are a creatinine clearance test and a serum creatinine test done together?

To get proper result: Creatinine clearance testing procedure and what measured is fully answered in prior question. The serum creatinine must be drawn right after the 24 hour urine collection to calculate how much creatinine is in serum and compare it to the total creatinine in the urine collection, to get an accurate measurement of renal function. ...Read more

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Why would the creatinine clearance test not be useful for detecting early renal disease?

Urine collection: Creatinine clearance requieres a full and precise 24 hour urine collection. The results can be falsely low if there is an undercollection, or falsely high if there is an overcollection. Also, creatinine can be affected by a high protein diet (the "ghoulash effect"). Such diets will raise serum creatinine. ...Read more

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I'm wondering why are both a creatinine clearance test and a serum creatinine test done?

Creatinine clearance: People who want to find out their renal function will collect a 24 hour urine for creatinine clearance. The blood sample is used to calculate the clearance of creatinine in the urine as it will be sent off for a creatinine level. Without it, the clearance of creatinine could not be calculated. The result of the test give the actual glomerular filtration rate of the patient. ...Read more

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Why are both a creatinine clearance test and a serum creatinine test done? Pain in the rear to collect.

See below: You are right, a collection of the 24 hour urine is cumbersome.It is possible to have a estimate of the GFR and creatinine clearance based on serum creatinine with a formula and tables which are easily available, which dose not require the urine collection. The 24 hour collection may be more accurate in extremes of weight etc and not necessary for most clinical scenarios. ...Read more

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Blood test: estimated creatinine clearance test (low), what could it indicate? EGFR & creatinine normal. Potassium & sodium low. 28yr/f

How do you FEEL?: Many (maybe most) pathologists and nephrologists aren't impressed with the current practice of labs estimate GFR, creatinine clearance and so forth from a spot creatinine. Some formulas include race "because black people are more muscular than white people" -- these were never intended to be applied to individuals. Frankly, if your others labs are healthy, I'd ignore it. ...Read more

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Creatinine clearance? What for?

Kidney function: Creatinine clearance is a calculation that serves as a measure of kidney function. There are 5 stages of kidney disease before end-stage. The stage guides treatment and allows the doctor to monitor changes over time. ...Read more

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What is a creatinine clearance?

Kdney function: A measure of your kidneys ability to clear waste products from the blood stream. It is calculated from your Creatinine level and takes your age, sex and weight into account. ...Read more

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How to boost your creatinine clearance?

Renal health: Creatinine clearance depends primarily on the glomerular filtration function of the kidney. There is no way to boost it above the normal level, nor is there any need for it. If your creatinine clearance is lower than normal, you ought to consult a nephrologist. For good health - Have a diet rich in fresh vegetables, fruits, whole grains, milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Drink enough water daily, so that your urine is mostly colorless. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form. Practice safe sex. ...Read more

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Creatinine clearance --what exactly is it?

It is a measure: Of creatinine, a breakdown product of muscle, and the efficiency of it's removal by functioning kidneys. It is measured by a blood testof creatinine, and a 24 hour urine collection to assess how much is cleared per hour. It is the gold standard of kidney function. ...Read more

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Is it ok to have creatinine clearance of 42 at 92 ?

Almost normal: It is normal to lose some filtering units with age so that after age 40 the creatinine clearance starts to fall. This will be accelerated by hypertension or obesity or diabetes but even in normal individuals it falls at a lower rate. At age 90 a creatinine clearance of about 60 mls per min would be expected so 42 is close to it. ...Read more

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What are the sources of error for creatinine clearance?

What are the sources of error for creatinine clearance?

Creatinine clearance: The most common cause is improper urine collection which means all the urine is not collected in the container. The other reason could be not collecting blood specimen for serum creatinine once you finished the urine collection. Another reason could be not collecting urine in proper container and the last reason can be not writing the correct total volume of the urine. ...Read more

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What does it mean when you have a low creatinine clearance?

Impairment: of kidney function. The kidneys are not filtering waste out of the blood as efficiently as they should. Most of the time low creatinine clearance is due to some sort of disease of the kidneys themselves like inflammation or decreased blood supply. Recurrent urinary tract infections can also damage the kidneys. Best to see a nephrologist for evaluation. Thanks for trusting HealthTap! ...Read more

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What is the formula for determing a creatinine clearance rate?

24 hour urine: 24 hour urine is collected to measure the amount of creatinine excreted in 24x60 minutes. This is then divided by the serum concentration of creatinine to estimate the volume of plasma cleared of creatinine in one minute. Creatinine clearance rate has mostly been replaced by estimated glomerular filtration rate, that requires only the measurement of serum creatinine. ...Read more

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What is the definition or description of: creatinine clearance?

What is the definition or description of: creatinine clearance?

Kidney Function: Creatinine clearance is used in clinical practice to give an estimate of overall kidney function, or glomerular filtration rate. Generally normal is considered 100 or above, but it goes down every year and elderly patients may have low clearance which is not abnormal. ...Read more

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If there is a decline in creatinine clearance, what does that mean?

If there is a decline in creatinine clearance, what does that mean?

Declining renal func: Creatinine clearance generally reflects kidney function.Depending upon the numbers severity can be estimated. ...Read more

Dr. Madhu Kandarpa
2,206 doctors shared insights

Creatinine (Definition)

Creatinine is a byproduct of creatine phosphate, which is present in muscles. Creatinine levels increase if the ...Read more