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Doctor insights on: Creatine Kinase Isoenzymes

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Elevated total creatine kinase with normal isoenzymes. What does this mean?

Elevated total creatine kinase with normal isoenzymes. What does this mean?

CPK: Ck is a polycomponent muscle enzyme. The ck mb is the muscle-brain part of ck total. That is why the lower value for mb. The lab normals would tell whether these are elevated or not. Elevations are usually from muscle damage and the mb is found in heart. ...Read more

Creatine Kinase (Definition)

Creatine kinase is an enzyme found in muscles throughout the body. There are different subtypes of the enzyme, called isoforms, which predominate in different organs. For instance, the isoform in skeletal muscles is different from that which is most heavily found in the heart muscle. A blood tests detects levels of this in the body, for example if ...Read more


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Blood draw immediately after a flu vaccine (intramuscular) - can this elevate the creatine kinase result? (lab value of 700+)

Blood draw immediately after a flu vaccine (intramuscular) - can this elevate the creatine kinase result? (lab value of 700+)

No: But if you had just exercised in the previous few hours that could do it. It's not a harmful level. If you are having chest pain or difficulty breathing or seeing dark reddish brown urine, you should see your doctor. ...Read more

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My husband has been diagnosed with having too much creatine kinase in his blood, what does this mean please?

My husband has been diagnosed with having too much creatine kinase in his blood, what does this mean please?

Muscle breakdown: It usually means that there was or is ongoing muscle breakdown of some sort. Ther are many causes of this, but a heart attack, rhabdomyalisis, exercise, blunt force trauma, etc can cause local or systemic breakdown. The lab doesn't say where or what kind. ...Read more

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Can you still workout hard if creatine kinase is high?

Can you still workout hard if creatine kinase is high?

Resolve cause first: High creatine kinase is due to muscle damage. It would be important to determine the cause of muscle damage before working out so that you do not add to the damage. ...Read more

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What can be the cause of low serum creatine kinase? level is 26 iu/L?

What can be the cause of low serum creatine kinase? level is 26 iu/L?

Means nothing: Reference ranges are set so that several percent of healthies fall outside on either end. Stop worrying. Ask your physician about what kind of aerobic fitness would be right for you. ...Read more

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Elevated total creatine kinase with normal isoenzymes. What does this mean?

CPK: Ck is a polycomponent muscle enzyme. The ck mb is the muscle-brain part of ck total. That is why the lower value for mb. The lab normals would tell whether these are elevated or not. Elevations are usually from muscle damage and the mb is found in heart. ...Read more

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What are the symptoms of high creatine kinase?

What are the symptoms of high creatine kinase?

None: In my series of medical students, almost all the men and a majority of the women who were even moderately focused on physical fitness had creatine kinase levels above reference range. Right or wrong, the lab's reference range assumes the person does not exercise. ...Read more

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What does the creatine kinase blood test looking for?

What does the creatine kinase blood test looking for?

Muscle injury: Creatine kinase is present in all types of muscles: skeletal, heart and smooth muscles. Any injury to the muscles will raise the level of this enzyme. Some drugs, e.g., statin can also increase the level. The level cannot be too low. ...Read more