Doctor insights on:
Cozaar Angiotensin Ii Blocker
Hypertension: Angiorensin ii is a potent vasoconstrictor and proinflammatory chemical that has effects on vascular endothelium that contribute to atherosclerosis and hypertension. In the heart it increases hypertrophy and increases arrhythmic potential. It stimulates aldosterone . It is formed through a chemical conversion of angiotensin i to angiotensin ii mediated by sympathetic activation of ace. ...Read more
AII vs aldo and salt: Aldo causes more Na retention and water follows salt. But depends on circumstances. AII is major drive to aldo production so if AII high get same effect if you don't die form the severe HTN from excess AII. Both can be counteracted if you eat less salt. I am a specialist in the renin angiotensin aldosterone system and happy to consult with you. ...Read moreSee 2 more doctor answers
Test: You can measure angiotensin two levels. I would talk to your cardiologist or renal specialist about the need to do this. ...Read more
Angiotensin II: Angiotensin ii stimulates the adrenal cortex to produce aldosterone which regulates salt and water reabsorption in the kidney. It is a vasoconstrictor and has effects to drive up BP through both these mechanisms. It potentates sympathetic neural output at the pregnant livonia level. ...Read more
CHF: These are secreted by the body intent on increasing intravascular volume. They can be an appropriate compensatory mechanism when volume is low, or they can aggravate hypertension and chf, when they become excessively secreted. ...Read more
If someone was to have low angiotensin II and low aldosterone would you expect to see a lower renin also?
Renin levels: If one has a low aldosterone and angiotensin ii, one would expect a high renin level. Renin leads to angiotensin i and ii synthesis. If those levels are low and the person is ambulatory, the person's renin would be expected to be high. For a diagram of the renin-angiotensin-aldosterone system go to this link; http://www.Google.Com/search?Hl=en;site=imghp;tbm=isch;source=hp;biw=2556;bih=1234;q=renin+angiotensin+system;oq=+angiotensin+sy;gs_l=img.1.1.0j0i5l9.576.4679.0.9029.16.9.0.188.8.131.52.974.0j5j1.6.0....0...1ac.1.35.Img..5.11.985.Luxw_l48srm#fa. ...Read more
Why does Primary hypoaldosteronism lead to increased renin and Angiotensin II, but secondary hypoaldosteroninim does not?
Renin-AT II-ALD axis: With primary (1°) hypoaldosteronism, feedback on the renin-angiotensin (AT) II-aldosterone (ALD) axis would cause the kidneys to increase renin and thereby AT II to try ^ adrenal ALD. In 2° hypoaldo, there is usually kidney damage (for example, due to diabetes) which decreases renin and hence AT II (which is produced in response to renin). This causes ALD (which depends on AT II) to v (hence 2°). ...Read moreSee 1 more doctor answer
If there is a normal level of renin, there should be a normal level of angiotensin II and aldosterone right? So low angiotensin II = low aldosterone?
Aldosterone: Not really. It depends upon sensitivity of adrenal galnds to angitensin ii. ...Read more
Is there anyway to increase angiotensin ii, my body does not produce it despite normal renin, autonomic nerve issue.
Meaningless: If your renin is normal, you don't need any higher angiotensin ii which is an intermediate step in the synthesis of renin. From you posts, it sounds like you might have hypothalamic/pituitary insufficiency - have you seen an endocrinologist? ...Read more
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