Doctor insights on:
Could A Bone Marrow Biopsy Cause Me Problems Later In Life
A bone marrow biopsy is taken from the pelvic bone. A coring needle is advanced into the bone, which allows one to extract a sliver of the bone marrow, the red part of the bone. It is cut and viewed under a microscope. A bone marrow aspirate, obtained with a syringe, is usually bone at the same time. These are done to diagnose blood problems or to check for tumors in ...Read more
Yes: Might a bone marrow biopsy, which occurs in region of the posterior iliac crest, cause chronic pain in this region; which many lay people term the "hip"? Chronic pain is uncommon & suggests ilio-lumbar ligament injury & associated sacroiliac joint instability. The same chronic injury occurs when Orthopedists ignorantly harvest iliac crest bone during vertebral spine fusion operations. ...Read more
Is there any condition that could cause both neutropenia and hypothyroidism? All orderedblood tests and bone marrow biopsy came back normal/negative.
Unrelated: Hypothyroidism is very common condition, so it is not uncommon to have other conditions that can coexist independent of each other. Neutropenia is often caused by bone marrow damage of some kind or other, although on rare occasions it can be congenital(since birth, cause unknown). The degree of neutropenia matters. So you should give us all the numbers of your CBC...such as WBC count & Neutrrophil ...Read more
Could splenic lymphoma exist even with Negative Bone marrow biopsy & negative PET/CT, but splenomegaly occur? Other causes has ruled out.
Lymphoma can,on rare occasions, involve spleen alone, sparing all other organs. But PET will show increased uptake(high SUV) and CT would show enlargement of Spleen.
So depending on your symptoms and the degree of enlargment of your spleen, your doctor may, somewhere along the line, consider removal of the spleen(splenectomy). But this step would only be taken if your spleen is causing U any harm ...Read more
If you have chronic anemia and doctors can't find the cause, is it common to get a bone marrow biopsy?
Not uncommon, in normocytic anemia if they want to see how the cells are generating RBC, whether it is making cells or not making cells. Have you also been tested for celiac disease, thyroid disease G6PD, and medications that can sometimes cause anemia as well? .
http://www.aafp.org/afp/2000/1115/p2255.html ...Read more
If blood work has not shown the cause of my polycythemia, will a bone marrow biopsy be helpful? My hematologist has mentioned it, but not done it.
It may or maynot: The diagnosis of polycythemia requires several criteria which are well-defined. They include CBC, Hb level, WBC level, platelets and Blood erythropoetin level. Send us the results and we can help you. Unless your Hb is above 17 grams, you can get a follow up CBC in 2-3 months and see if it is rising. ...Read more
I have been diagnosed with IGM Kappa Mgus when I turned 35. Spike 2g/dl. No other problem and bone marrow biopsy clean. What is risk of progression?
Low: Less than one percent per year. Plan for a normal life. ...Read more
What might be the cause of an abs. Neutrophil count of <500 (when all other bc counts are within normal ranges)? Is bone marrow biopsy the next step?
Have APS , does it Cause High B2M? Normal CT/PET and Bone marrow Biopsy. High LDH, Spleenomegaly, Normal SPEP, Night sweat, tired, Low platelete& RBC
The B2M protein is "non-specific: and not necessarily associated with APS I am going to refer your question to one of our HEMATOLOGY/ONCOLOGY experts. This referral should not frighten you! It is simply to help you find out more about your clinical situation.
Hope this helps
Dr Z ...Read more
Just a few days: This may cause some soreness at the site and bruising, swelling and tenderness. Usually this will resolve in a couple of day. One could understand up to a week depending on health conditions, any difficulty with the procedure and any other risk factors. If you are concerned, get it checked out. Infection would be my biggest concern, then a large hematoma would be my next one. Use ice packs! ...Read more
Many Indications: Bone marrow biopsy is most useful in diagnosis and staging of blood cancers (leukemia, lymphoma, multiple myeloma, etc). Also, indicated for evaluating unexplained anemia, leukopenia, thrombocytopenia, pancytopenia, or unexplained elevated blood counts. It is also useful for fever of unknown origin, or as a confirmation that bone marrow transplantation is successful. ...Read more
Short term: Should be no more than a few days; and that is on the longer side of the estimate. ...Read more
Depends / 1 week: It depends. If the bone marrow is "packed" with cancer cells it may be obvious on an initial review by a hematologist and/or hematopathologist. However, for a new diagnosis i generally tell patients it may potentially be a week for special stains/studies and "send out" studies to fully characterize the bone marrow. ...Read more
Bone marraw biopsy: Bone marraw biopsy is somewhat uncomfortablel. But the risk of general anethesia is too high. Using local numb medicine will decrease the pain. ...Read more
Anesthesia: Yes, you could have an anesthesiologist involved if you arranged this with the physician ordering the test. ...Read more
Bone marrow biopsy?:
I am not clear what you are asking--do you want to know how much bone marrow is removed during a bone marrow biopsy?
Generally, 5-15 cc's of marrow is removed during a bone marrow aspiration and then a 2-3 cm small piece of the bone marrow is removed for the biopsy.
If you were trying to get other information please add a more detailed question. ...Read more
Change in components: A bone marrow biopsy in a normal person will find the pattern of cells most often seen in a healthy person of that age. This would include red cells and their precursers (builders), white cells & precursers, platelet precursers & others. In illness, the pattern changes, and some or all may be abnormal. Tumor cells may take over every space& or few if any normal cells may be seen. ...Read more
Depends: If your receive conscious sedation, you will not have noticeable pain during the procedure. Afterward, you may have pain for a day or so unless there is an untoward complication. I had one and it hurt minimally for 24 hours. I had conscious sedation. ...Read more
Biopsy is tissue removed by needle or cutting to remove part of a body part. It is usually a small amount of material that is processed by a pathologist. Most of the time it is stained and looked at through a microscope to arrive at a diagnosis. Special processes are done for some tissues or problems. The purpose is to tell what the problem is (diagnosis). ...Read more
Bone marrow is the flexible tissue found in the interior of bones. In humans, red blood cells are produced in the heads of long bones, in a process known as hematopoesis. On average, bone marrow constitutes 4% of the total body mass of humans; in an adult weighing 65 kilograms (140 lb), bone marrow accounts for approximately ...Read more
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