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Doctor insights on: Cortisols Role In Hasmimotos Thyroiditis

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Do elevated levels (1300) of IgE play a role in autoimmune diseases?

Do elevated levels (1300) of IgE play a role in autoimmune diseases?

Probably not: High ige is associated with allergy, smoking and some immune deficiency diseases. It is usually not associated with autoimmune diseases. ...Read more

Dr. Quang Nguyen
1,039 doctors shared insights

Inflammation Of The Thyroid (Definition)

Several common forms of thyroiditis. Subacute thyroidits is from a virus. Your thyroid is tender, transient hyperthyroidism, but then resolution. Hashimotos thyroiditis is usually without pain, eventually causes hypothyroidism, but can coexist with graves hyperthyroidism. Two other forms are post partum thyroiditis and "painless" thyroiditis; transient hyper followed by ...Read more


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I have hypocretin deficient narcolepsy which reduces TSH levels along with autoimmune hypothyroidism. Is the TSH test reliable to gauge my thyroid?

I have hypocretin deficient narcolepsy which reduces TSH levels along with autoimmune hypothyroidism. Is the TSH test reliable to gauge my thyroid?

Not always: TSH is not always a reliable test, because it relies on what the pituitary thinks, but different tissues may have different sensitivity to thyroid hormone. In addition, some people make too much reverse T3 (liothyronine), (liothyronine) which can block the action of T3 (liothyronine). Google "stop the thyroid madness" ...Read more

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In hashimoto thyroiditis why is there an initial increase in thyroid levels?

In hashimoto thyroiditis why is there an initial increase in thyroid levels?

Mechanism: The thyroid has 2 months of thyroid hormones stored inside it. When it gets inflamed (thyroidtis), it can't hold on to the thyroid hormones and the hormones leak out into the blood stream. That's why you have high level at the beginning. Once all the hormone is leaked out, there is no hormones left and the body has to make the hormone again which is why you become low. ...Read more

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Hypothyroidism w/ elevated tpo antibodies, low t, adrenal insufficiency... Synthroid (thyroxine) & testosterone hasn't helped. Can I have an autoimmune disease?

Hypothyroidism w/ elevated tpo antibodies, low t, adrenal insufficiency... Synthroid (thyroxine) & testosterone hasn't helped. Can I have an autoimmune disease?

You do have it: Elevated tpo antibodies confirms you have autoimmune thyroiditis. This is often triggered by environmental toxins ;/or infections. You will likely benefit from adding liothyronine to your regimen ; treating adrenal problems with cordyceps, rhodiola etc. I advise consulting with a holistic doc. See http://abt.Cm/18gpb3a ; http://bit.Ly/15k26u8 ; http://bit.Ly/17nx2ax ; http://bit.Ly/16blg0r. ...Read more

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downs,systemic rheumatoid arthritis, anemia tsh t4 normal has thyriod antibodies hyperthyroid why

  downs,systemic rheumatoid arthritis, anemia tsh t4 normal has thyriod antibodies hyperthyroid why

Autoimmune disorders: like Rheumatoid Arthritis, diabetes & thyroiditis have an ^ed incidence in children with Down Syndrome (DS). A normal Free T4 & ^ed Ultrasensitive TSH indicates sub-clinical HYPOthyroidism that can become clinical. Macrocytosis, large RBC's, in infants with DS remains lifelong in 2/3rds. It can be associated with anemia from low Vitamin B12 & Folate (folic acid) or iron levels, hypothyroidism or leukemia. ...Read more

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I have many thyroid symptoms but my test is in the nor. Range TSH 1.35(nov) 1.45(jan) T4 1.16 T3 (liothyronine) 3.55 thyroid peroxidase (tpo) ab<6 antithyroglobul<20

I have many thyroid symptoms but my test is in the nor. Range TSH 1.35(nov) 1.45(jan) T4 1.16 T3 (liothyronine) 3.55 thyroid peroxidase (tpo) ab<6 antithyroglobul<20

Depends: Does not sound thyroid, although reverse T3 (liothyronine) was not checked. Could be adrenals, could be lyme. Could be vitamin deficiencies. More information: http://drfairchild.Blogspot.Com/2012/12/proper-thyroid-testing.Html http://drfairchild.Blogspot.Com/2012/12/b12-deficiency.Html. ...Read more

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What is the significance of radioactive iodine scan in various throid diseases like myxedema, hashimoto's thyroiditis and graves disease?

What is the significance of radioactive iodine scan in various throid diseases like myxedema, hashimoto's thyroiditis and graves disease?

Hot vs. cold nodule: Iodine uptake by thyroid tissue depends on functioning cells. The most common use for thyroid scan is to assess if a nodule is functional or not. A functional/hot nodule may cause hyperthyroidism but is not likely to be malignant. See this site for more info. http://www.nlm.nih.gov/medlineplus/ency/article/003829.htm. ...Read more

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I have high tpo, high thyroglobulin and in range TSH and T4 hashi s or graves ?

I have high tpo, high thyroglobulin and in range TSH and T4 hashi s or graves ?

Neither.: If you have normal TSH and T4 you have neither of those diseases yet. You may develop hashimoto's in the future but may not. Progression should be monitored with TSH and possibly ft4. ...Read more

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High cortisol level in evening , high acth level131pg...Mild hypertension.., no mass in suprarenal gland , cuahing appearance..Cause?

High cortisol level in evening , high acth level131pg...Mild hypertension.., no mass in suprarenal gland , cuahing appearance..Cause?

Possible pituitary: Having a high cortisol with a high acth level is indicative of acth dependent cushings disease. This is a rare disorder due to a pituitary adenoma making too much acth. You may or may not be able to see an abnormality on ct scan or MRI of the pituitary. You should do Dexamethasone suppression testing to confirm the diagnosis. Sometimes the acth is coming from a source outside of the pituitary. ...Read more

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Why does thyroid replacement therapy in hypoadrenalism cause adrenal crisis?

Why does thyroid replacement therapy in hypoadrenalism cause adrenal crisis?

Great question!: Even people with adrenal problems often make a little bit of cortisol. This little bit can be enough to keep them from getting very sick. In hypothyroidism the body's need for cortisol goes down and the little bit you make lasts longer. So if a person has both thyroid and adrenal disease, treating the thyroid without treating the adrenal problem first causes the little cortisol to run out quicker. ...Read more

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Thyroid swelling. Ultrasound heterogenous thyroid parynchema with hypervascularity. Blood test-normal tsh t4 t3 (liothyronine) etc but >1300 TPo antibodies?

Thyroid swelling. Ultrasound heterogenous thyroid parynchema with hypervascularity. Blood test-normal tsh t4 t3 (liothyronine) etc but >1300 TPo antibodies?

Hard to say: Ive yet to have anyone NOT have elevated TPo but I havent sent many. The standard answer would be that it likley is GRAVES disease starting but if there arent a lot of symptoms and the labs are normal you wouldnt give treatment. Retesting if symptoms and at about every 3 months. ...Read more

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Not well, enlarged thyroid, two benign nodules that are autonomous, TSH low, T4 low end of normal, thyroglobulin antibodies present - thoughts?

Not well, enlarged thyroid, two benign nodules that are autonomous, TSH low, T4 low end of normal, thyroglobulin antibodies present - thoughts?

Suggests autoimmune: Your symptoms and lab values suggest an autoimmune inflammatory problem. You need expert evaluation and should see a qualified doctor as soon as possible. Doctors that specialize in thyroid disorders are endocrinologists. However, many medicine doctors from family medicine and internal medicine are very adept at helping with thyroid disease. ...Read more

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Some research suggests patients with cushings can have positive anti-pituitary antibodies targeting acth producing cells and this autoimmunity can stimulate acth adenoma formation. Is this correct?

Some research suggests patients with cushings can have positive anti-pituitary antibodies targeting acth producing cells and this autoimmunity can stimulate acth adenoma formation.  Is this correct?

Doubt it: People with pituitary adenomas of all sorts tend to have pituitary autoantibodies but these can't cause the mutations that cause the tumors ; are probably just the result for the normal gland being damaged. Since the type of tumor has no correlation with antibody presence, this supports this common-sense idea. New review pituitary. 15(4):490-4, 2012 dec. ...Read more

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Can my carrier status of congenital adrenal hyperplasia (21-Hydrolaxe deficiency, salt-wasting) explain my high basal cortisol?

Can my carrier status of congenital adrenal hyperplasia (21-Hydrolaxe deficiency, salt-wasting) explain my high basal cortisol?

No: Spot "basal cortisol" levels mean nothing except in context. They help rule some things in and some things out. The highest basal cortisol levels have been found in soldiers in the battlefield and medical students in exams. Ignore all "pop" sites relating to pituitary / adrenal disease and remember that reference ranges are set so that many healthies fall outside on either end. ...Read more