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Doctor insights on: Cortisol Saliva Lcmsms

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I have taken two saliva cortisol tests. AM is 6-7, noon .3-4, 4pm .3-2, bedtime .3-1. I respond to stress poorly lately. Not sure where to get help.

I have taken two saliva cortisol tests. AM is 6-7, noon .3-4, 4pm .3-2, bedtime .3-1. I respond to stress poorly lately. Not sure where to get help.

Stress saliva: 35 F from LA SHOWS salivary results. States she respomds to stress poorly. Not sure where to get help? ANS:Tje response to stress is complicated. But that is what I do. So recommend second opinion with me ...Read more

Dr. Troy DeLong
20 doctors shared insights

Saliva Cortisol (Definition)

Blood cortisol is used to help diagnose adrenal insufficiency and addison disease, conditions in which the adrenal glands do not function properly. Salivary cortisol testing is a suitable alternative to serum cortisol. Cortisol output by your adrenal glands is one of the most reliable indicators of your adrenal function and how well your body ...Read more


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Saliva cortisol test - how accurate can a saliva test be?

Saliva cortisol test - how accurate can a saliva test be?

Check normal range: Accuracy of all tests is an issue and if the test does not reflect what appears clincally it may be need to be repeated. Accuracy depends on sensitivity and specificity. Trials need to be run comparing blood and saliva to determine which is best... And which is best for the money. ...Read more

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What is the definition or description of: saliva cortisol?

What is the definition or description of: saliva cortisol?

Serum alternative: Blood cortisol is used to help diagnose adrenal insufficiency and addison disease, conditions in which the adrenal glands do not function properly. Salivary cortisol testing is a suitable alternative to serum cortisol. Cortisol output by your adrenal glands is one of the most reliable indicators of your adrenal function and how well your body is dealing with stress. ...Read more

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Why is my saliva cortisol result so high? Is saliva testing not as accurate?

High cortisol: High cortisol may be due to a number of conditions, including a tumor in the pituitary gland or adrenal gland(s), stress, pain, illness, or taking steroids, or something that interferes with the test. The only way to find out what is causing your cortisol level to be high is to work together with a doctor. ...Read more

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I received slightly high saliva cortisol levels from recent test. What is a good approach to deal with this?

I received slightly high saliva cortisol levels from recent test.  What is a good approach to deal with this?

Get blood tests: If you have clinical symptoms, have your doc to blood cortisol levels and maybe a morning level after a dose of synthetic cortisone (dexamethasone) the nite before, or check 24-hour urinary cortisol level. A single mildly abnormal saliva cortisol test is most likely of no significance -- but should be followed up. ...Read more

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Seeing endo soon, but i would like to understand my saliva cortisol test result. 1.94 mcg/dl (rr is < or = 0.09 mcg/dl) cushings r/o in 2012.

Seeing endo soon, but i would like to understand my saliva cortisol test result. 1.94 mcg/dl (rr is < or = 0.09 mcg/dl)  cushings r/o in 2012.

Tough diagnosis: Cushing's can be very difficult to diagnose. It is not unusual for someone to have problems for several years because the tests can vary over time, and be equivocal for a long time. That being said, i can't really interpret a single test result without knowing a lot more about the timing and situation under which it was collected. Best to wait until you see your endocrinologist. ...Read more

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Saliva cortisol tests are abnormally low. Serum cortisol tests are normal. Dr says i don't need an acth stim test due to serum results. Agree?

Yes: If your saliva cortisol tests are low, then you have adrenal insufficiency. Acth stim test will only help determine if the cause is in the adrenal glands, pituitary gland or hypothalamus. Without other hormonal abnormalities or abnormal levels of sodium or potassium, this test is generally not needed and treatment for the adrenal insufficiency can be done. ...Read more

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Saliva cortisol test says low in mornings , normal day , elevated at night is this adrenal insufficiency ?

Saliva cortisol test says low in mornings , normal day , elevated at night is this adrenal insufficiency ?

No: Salivary cortisol is a poor measurement of adrenal insufficiency and the people that offer it are not for you. See a real endocrinologist if you think you have it. Do not waste money on phony tests. ...Read more

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Saliva (Definition)

The clear, viscous fluid secreted by the salivary and mucous glands in the mouth. Saliva contains water, mucin, organic salts, and the digestive enzyme ptyalin. It serves to moisten the oral cavity, to initiate the digestion of starches, and to aid in the chewing and swallowing of food. Approximately 1 to 1.5 l ...Read more