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Doctor insights on: Cortisol Saliva

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What do I do if my cortisol saliva test came back double the normal rate?

What do I do if my cortisol saliva test came back double the normal rate?

See you MD: All medical tests are subject to errors. If this is the first time you have had an abnormal reading it would be best to rerun the test. Various conditions may cause the cortisol levels in the saliva to increase. It would be best to consult with your md to properly evaluate the cause of these findings. ...Read more

Mouth (Definition)

Mouth (mouth) " n. Pl. Mouths 1. A. The body opening through which an animal takes in food. B. The cavity lying at the upper end of the alimentary canal, bounded on the outside by the lips and inside by the oropharynx and containing in higher vertebrates the tongue, gums, and teeth. C. This cavity regarded as the source of sounds and speech. D. The opening to any cavity or canal ...Read more


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I had a cortisol saliva test done and the morning&lunch values were low normal, evening was right on and night was very high, could this be cushings?

Cushing's not likely: This would be very atypical. Low cortisol levels are not typical. This could be clarified with a 24 hr urine collection for free cortisol or an overnight Dexamethasone suppression test. ...Read more

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Cortisol saliva test very high, but DEXA suppression test normal. Have had fatigue, low BP, weakness for years. Which test to believe, and what now?

Cortisol saliva test very high, but DEXA suppression test normal. Have had fatigue, low BP, weakness for years. Which test to believe, and what now?

Cushing's: There are several ways to screen for Cushings: 24 hr urine cortisol, overnight dex suppression, and midnight salivary cortisol. All would be altered if you took a steroid suppository. All need confirmation from other tests. Intermittant steroid use can cause symptoms of Cushing's, but no reason to think there is a tumor if you are taking steroids. You may need to see an Endocrinologist. ...Read more

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Cortisol saliva was very high, but I feel great when on steroids and have LOW bp, fatigue, weakness. How can it be HIGH cortisol w/these symptoms?

Cortisol saliva was very high, but I feel great when on steroids and have LOW bp, fatigue, weakness. How can it be HIGH cortisol w/these symptoms?

Depends on time: You need to see all of the cortisol levels four times a day in order to see what the overall story is. You may have one high and the rest low and having stressors throughout the day hindering you The prednisone also is causing problems with your natural levels See a functional medicine provider to assess your levels and help you correct any problems so you begin to feel better ...Read more

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I have had 4 fna biopsies to show follicular neoplasm, however my molecular test shows 98% benign. My doctor wants to still do the tt or partial. I'm curious if molecular tests are accurate? My cortisol saliva tests shows dropping off, insulin 34 h?

I have had 4 fna biopsies to show follicular neoplasm, however my molecular test shows 98% benign. My doctor wants to still do the tt or partial. I'm curious if molecular tests are accurate? My cortisol saliva tests shows dropping off, insulin 34 h?

Second opinion: Not sure if you are mentioning fine needle aspiration of the thyroid gland?
If so John Hopkins in number 1 in US for ENT as ranked in US News and World report.
Consider a second opinion with them if it is your thyroid. If not clarify question and resubmit. ...Read more

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Saliva cortisol test - how accurate can a saliva test be?

Saliva cortisol test - how accurate can a saliva test be?

Check normal range: Accuracy of all tests is an issue and if the test does not reflect what appears clincally it may be need to be repeated. Accuracy depends on sensitivity and specificity. Trials need to be run comparing blood and saliva to determine which is best... And which is best for the money. ...Read more

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What is the definition or description of: saliva cortisol?

What is the definition or description of: saliva cortisol?

Serum alternative: Blood cortisol is used to help diagnose adrenal insufficiency and addison disease, conditions in which the adrenal glands do not function properly. Salivary cortisol testing is a suitable alternative to serum cortisol. Cortisol output by your adrenal glands is one of the most reliable indicators of your adrenal function and how well your body is dealing with stress. ...Read more

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Why is my saliva cortisol result so high? Is saliva testing not as accurate?

Check normal range: Saliva testing is an emerging science that needs to be encouraged. Scientist are becoming extremely accurate at detecting miniscule concentrations of molecules and with a very small amount of diagnostic fluid. Blood is much more expensive to sample and painful and exposes the patient to injury. Saliva is thee preferrred method of donating a sample. The cost of medical care will go down. ...Read more

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I received slightly high saliva cortisol levels from recent test. What is a good approach to deal with this?

I received slightly high saliva cortisol levels from recent test. What is a good approach to deal with this?

Get blood tests: If you have clinical symptoms, have your doc to blood cortisol levels and maybe a morning level after a dose of synthetic cortisone (dexamethasone) the nite before, or check 24-hour urinary cortisol level. A single mildly abnormal saliva cortisol test is most likely of no significance -- but should be followed up. ...Read more

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I have taken two saliva cortisol tests. AM is 6-7, noon. 3-4, 4pm. 3-2, bedtime. 3-1. I respond to stress poorly lately. Not sure where to get help.

Stress saliva: 35 F from LA SHOWS salivary results. States she respomds to stress poorly. Not sure where to get help? ANS:Tje response to stress is complicated. But that is what I do. So recommend second opinion with me ...Read more

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Seeing endo soon, but I would like to understand my saliva cortisol test result. 1.94 mcg/dl (rr is < or = 0.09 mcg/dl) cushings r/o in 2012.

Seeing endo soon, but I would like to understand my saliva cortisol test result. 1.94 mcg/dl (rr is < or = 0.09 mcg/dl) cushings r/o in 2012.

Tough diagnosis: Cushing's can be very difficult to diagnose. It is not unusual for someone to have problems for several years because the tests can vary over time, and be equivocal for a long time. That being said, I can't really interpret a single test result without knowing a lot more about the timing and situation under which it was collected. Best to wait until you see your endocrinologist. ...Read more

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Saliva cortisol tests are abnormally low. Serum cortisol tests are normal. Dr says I don't need an acth stim test due to serum results. Agree?

Saliva cortisol tests are abnormally low. Serum cortisol tests are normal. Dr says I don't need an acth stim test due to serum results. Agree?

Yes: If your saliva cortisol tests are low, then you have adrenal insufficiency. Acth stim test will only help determine if the cause is in the adrenal glands, pituitary gland or hypothalamus. Without other hormonal abnormalities or abnormal levels of sodium or potassium, this test is generally not needed and treatment for the adrenal insufficiency can be done. ...Read more

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What could cause excess cortisol in the saliva and swollen parotid gland?

Cushings Disease: There are many conditions that can be related to the question you are asking. It is best to see your internist for a thorough evaluation and diagnosis. For more information regarding cushings syndrome you might check - neurosurgery. Stanford. Edu/pituitary/cushings_syndrome. Html and for salivary cortisol see: macses. Ucsf. Edu/research/allostatic/pdf/faqs-salivcort. Pdf. ...Read more

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Saliva cortisol test says low in mornings, normal day, elevated at night is this adrenal insufficiency?

Saliva cortisol test says low in mornings, normal day, elevated at night is this adrenal insufficiency?

No: Salivary cortisol is a poor measurement of adrenal insufficiency and the people that offer it are not for you. See a real endocrinologist if you think you have it. Do not waste money on phony tests. ...Read more

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My holistic doctor did a saliva cortisol test throughut the day. The results tell that I have adrenal fatigue. The doctor wants me to take adrenotone plus andphosphotidyleserine. Is it a good idea to take these?

My holistic doctor did a saliva cortisol test throughut the day. The results tell that I have adrenal fatigue. The doctor wants me to take adrenotone plus andphosphotidyleserine. Is it a good idea to take these?

Skeptical.: While promoted by various alternative medicine sites and "holistic" healers, adrenal fatigue isn't an accepted medical diagnosis. Keep a skeptical eye towards anything that sounds too good to be true - including supplements (especially if marketed by the doc). Supplements are largely unregulated - their purity and safety aren't tested. Most are useless. Common sense diet and exercise is best. ...Read more

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Used a mild hydrocortisone suppository on day of saliva cortisol test. Levels came back very high, dr is convinced is cushing's. suppository to blame?

Used a mild hydrocortisone suppository on day of saliva cortisol test. Levels came back very high, dr is convinced is cushing's. suppository to blame?

Not clear: Hi. I'm not sure why you're taking rectal hydrocortisone (HC). Hi dose exogenous glucocorticoids can cause Cushing's. However, rectal absorption of HC is poor compared to oral. If rectal dose was low, it seems unlikely it caused a high salivary cortisol. How long after suppository was saliva test collected? You need to stay off HC, do 24-hr urine cortisol, cortisol and ACTH with sex suppression. ...Read more

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I had elevated cortisol levls on a saliva test what does this mean?

I had elevated cortisol levls on a saliva test what does this mean?

Midnight?: Hi. Was it a midnight salivary cortisol? Let me assume it was (I hate to assume, but no details!), since there's no other legitimate use for a salivary cortisol test). It midnight salivary cortisol is high, it means your body has lost diurnal regulation of cortisol secretion, a hallmark of Cushing's Syndrome. It's part of a comprehensive Cushing's work up. Good luck! ...Read more

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I drink 3 liter/day and I also have dry eye syndrome. Did saliva test cortisol. Took me 20 minutes to produce 5ml saliva. Problem? R/o Sjogren?

I drink 3 liter/day and I also have dry eye syndrome. Did saliva test cortisol. Took me 20 minutes to produce 5ml saliva. Problem? R/o Sjogren?

Sjorgrens Testing: Drinking more water will not correct dry eye. You may want to try Restasis drops for this problem. See your local ophthalmologist for sure ...Read more

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What to do if I have very low cortisol blood levels but very high saliva, both the same day and time, why is that?

What to do if I have very low cortisol blood levels but very high saliva, both the same day and time, why is that?

CBG: Hi. There is a blood protein that binds cortisol called cortisol-binding globulin (CBG). Some people are genetically lacking CBG, so that large fraction of bound (kind of inert) cortisol is missing, and their cortisol blood levels are much lower. CBG does not go into saliva, but cortisol does. Without knowing more details, that could account for the differences. ...Read more

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Which of the following accurately predicts problems with cortisol levels blood test, 24 hr urine or midnight saliva swab?

Which of the following accurately predicts problems with cortisol levels blood test, 24 hr urine or midnight saliva swab?

Depends: Blood cortisol is useful in the diagnosis of cushings (hypercortisolemia) or adrenal insufficiency. A 24 hr urine cortisol is helpful to diagnose excess cortisol. Saliva cortisol is only helpful in diagnosing excess cortisol, not adrenal insufficiency. If a blood cortisol level is low, further evaluation is required to establish if your adrenal function is truly low. ...Read more

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Why are saliva and urine tests for cortisol only valid for high cortisol? Why don't endocrinologists feel saliva testing is valid for low cortisol?

Because it's not: There is a "pop" school of independent medical thought that holds that people who feel somewhat unwell have "hypophyseal-pituitary-adrenal axis syndrome" / "adrenal fatigue" and will screen for this on a spot salivary cortisol & Rx some herbals or vitamins. The danger of this hokey diagnosis is that you'll miss a real explanation -- emotional or physical -- for your symptoms. ...Read more

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I had my cortisol levels measured through a lab online (saliva test). My 4 values throughout the day were (ng/ml) 3.09 0.63 0.17 0.13 I've been very fatigued. Are these normal levels?

I had my cortisol levels measured through a lab online (saliva test). My 4 values throughout the day were (ng/ml) 3.09 0.63 0.17 0.13 I've been very fatigued. Are these normal levels?

Normal levels?: Adult females, ages 31-50
am range 0.094 - 1.515 ug/dl pm range nd - 0.181 ug/dl are you sure your values are ng/ml? Please check with an endocrinologist! Good luck! ...Read more

Saliva (Definition)

The clear, viscous fluid secreted by the salivary and mucous glands in the mouth. Saliva contains water, mucin, organic salts, and the digestive enzyme ptyalin. It serves to moisten the oral cavity, to initiate the digestion of starches, and to aid in the chewing and swallowing of food. Approximately 1 to 1.5 l ...Read more