Doctor insights on:
ACTH ALDO Cortisol: I have seen two families in which ACTH is the major driver for aldo production. They have the syndrome called GRA (Glucocorticoid Remedial Aldosteronism) caused by a cross over mutation in the genes controlling aldo production so that the major controller of aldo is ACTH. As you are young and making this question if you also have HTN your team should consider this. Many do not have low K. ...Read moreSee 1 more doctor answer
Mouth (mouth) " n. Pl. Mouths 1. A. The body opening through which an animal takes in food. B. The cavity lying at the upper end of the alimentary canal, bounded on the outside by the lips and inside by the oropharynx and containing in higher vertebrates the tongue, gums, and teeth. C. This cavity regarded as the source of sounds and speech. D. The opening to any cavity or canal ...Read more
Poor correlation: Hi. Oral cortisol (aka hydrocortisone) does not reliably affect ACTH secretion nor aldosterone levels. That is somewhat unfortunate for those of us treated adrenal insufficiency, since determination of proper dose is based solely on clinical response, and not labs. Aldosterone is driven by the renin-angiotensin system bypassing the pituitary. UIHC is excellent, so you have great docs close at hand ...Read more
43 yo f, afternoon cortisol high, cortisol suppression test high, CT of adrenal glands normal. Other causes of elevated cortisol?
Controversial: This is being marketed over the internet as an alternative to serum hormone testing from blood draws. Many studies have shown the results to be inconclusive. Meet with a physician to discuss your concerns and let them recommend testing modalities appropriate to your situation. ...Read moreSee 1 more doctor answer
Lab tests: SED 25, glucose 80, luteinizing horm 5.0, thyroid stimulating horm 0.966, FSH 7.1. All on 12/17/14. Related to chronic hives?
No: See a dermatologist. Do you take aspirin or any meds or any herbs or vitamins, etc.? Hives for over 6 weeks is termed chronic urticaria and is usually not allergy. Meanwhile you can try Zyrtec (cetirizine) (cetirazine) 1 or 2 a day. Sometimes larger doses may be used. There is a chance it could make you sleepy. ...Read more
Adrenal gland: yesGet a more detailed answer ›
Most helpful test: The 24 urine cortisol testing is one of the most sensitive tests and gives a better picture over the course of the day instead of just getting a sample from you a single time. There are blood tests and saliva tests which can be falsely be falsely elevated or falsely low depend L depending on your other medications and the time the test is performed. The best is to see an endocrinologist to help. ...Read more
Which of the following accurately predicts problems with cortisol levels blood test, 24 hr urine or midnight saliva swab?
Depends: Blood cortisol is useful in the diagnosis of cushings (hypercortisolemia) or adrenal insufficiency. A 24 hr urine cortisol is helpful to diagnose excess cortisol. Saliva cortisol is only helpful in diagnosing excess cortisol, not adrenal insufficiency. If a blood cortisol level is low, further evaluation is required to establish if your adrenal function is truly low. ...Read more
Test adrenal fxn.: This test is to check on whether or not your adrenal glands are working right. The acth action is to increase production and release of corticosteroids. In the test, a small amount of synthetic acth is injected and the amount of cortisol the adrenals produce in response is measured. This is used to check for things like primary and secondary adrenal insufficiency, and addison's disease. ...Read more
Hormones: A tropic hormone is a hormone secreted by one gland and then stimulates another gland; for example, the pituitary makes TSH, which targets the thyroid and causes the thyroid to make T4 and T3 (liothyronine). The thyroid hormones (T4, T3 (liothyronine)) target other organs (heart, CNS, GI, etc), but not really other glands, so are not really tropic hormones. ...Read more
Be careful: Salivary gland cortisol is an evidence-based screening test for cushingism (not so much for addisonism), but it does not permit a diagnosis to be made. If a fringe practitioner diagnoses you with "adrenal fatigue syndrome" based on a spot salivary cortisol and offers you supplements, you need to put your hand over your wallet. ...Read moreSee 1 more doctor answer
If cortisol blood test came back normal, could salivary cortisol lab show diff? Dr is checking for adrenal fatigue.
It depends: This is serious business. The real question is, "Do you have Addison's disease?" A spot serum cortisol is often normal even in Addison's, making the diagnosis tricky. There are decision levels for the easy screens that your physician is aware of, but if there's any doubt, you'll probably get an ACTH stimulation test. Avoid "pop"/"fad" diagnoses like "HPA axis fatigue". Best wishes. ...Read more
How high?: It's important to know how high the tests were above the normal range (were they clinically significant?). Cortisol is produced by the adrenal glands which is under control by the pituitary. The problem could be either one. Your doctor who ordered the cortisol should be able to tell you the next step of workup. If the tests were indeed very high, you will need more testings before treatment. ...Read moreSee 1 more doctor answer
Specialized glands: Brain signals regulateleydig cells in the testes which secrete testosterone. In males, most of the testosterone is produced in the testes and a small amount is derived from the adrenal gland. In females, small amounts of testosterone are produced in the ovaries and derived from the adrenal gland. ...Read moreSee 1 more doctor answer
The clear, viscous fluid secreted by the salivary and mucous glands in the mouth. Saliva contains water, mucin, organic salts, and the digestive enzyme ptyalin. It serves to moisten the oral cavity, to initiate the digestion of starches, and to aid in the chewing and swallowing of food. Approximately 1 to 1.5 l ...Read more