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Doctor insights on: Cortisol Binding Globulin

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Does Effexor (venlafaxine) raise shbg (sex hormone binding gobulin) levels?

Does Effexor (venlafaxine) raise shbg (sex hormone binding gobulin) levels?

Interesting question: I have not found any publications specifically studying this question. Antipsychotics and Prozac (fluoxetine) can affect prolactin, potentially changing sex hormone levels. This may or may not relate to shbg levels, though. I did find one small (20 patients) study online concerning low testosterone levels and antidepressant-induced sexual dysfunction: http://tinyurl.Com/mk84cfr further research needed. ...Read more

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What is plasma acth cortisol response?

What is plasma acth cortisol response?

Test adrenal fxn.: This test is to check on whether or not your adrenal glands are working right. The acth action is to increase production and release of corticosteroids. In the test, a small amount of synthetic acth is injected and the amount of cortisol the adrenals produce in response is measured. This is used to check for things like primary and secondary adrenal insufficiency, and addison's disease. ...Read more

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Inorgan.Phosphate0.77, serum total protein63, serum globulin14, all slightly low. Norm. Calcium &albumin.Tsh9.25, known hypothyroidism. Further tests?

Inorgan.Phosphate0.77, serum total protein63, serum globulin14, all slightly low. Norm. Calcium &albumin.Tsh9.25, known hypothyroidism. Further tests?

TSH is WAY high!: Must get on a higher dose of synthroid (thyroxine). This can be life threatening, get treated asap, ! other thyroid tests need to be done to know what needs to be done, and to come to a diagnosis. ...Read more

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What can decrease the serum levels of sex hormone binding globulin?

What can decrease the serum levels of sex hormone binding globulin?

Exercise & fat loss: Sex hormone binding globulin (shbg) is related to estrogen levels which are related to body fat. So the non-drug way to get around this is via exercise & nutrition in order to get rid of excess body fat, esp around your gut. If you can't lower your estrogen levels enough, some physicians (myself included) will attempt an off-label trial of an aromatase inhibitor to stop your body's conversion of t. ...Read more

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Plasma Vitamin D <4.2 ng/mL Serum Vitamin B12 -197 Serum TSH-2.805 Serun Alkaline Phosphatase-356 WBC-3300 MCV-103 MCH-34 Platelet-141k?

Plasma Vitamin D  <4.2 ng/mL
Serum Vitamin B12  -197
Serum TSH-2.805
Serun Alkaline Phosphatase-356
WBC-3300
MCV-103
MCH-34
Platelet-141k?

Need Vits D3 and B12: You are severely deficient in Vitamins D3 and B12. I recommend 10,000 IU of Vit D3 per day, and 1,000 mcg methylcobalamin each day. Your D3 levels should be 60-70 ng/dl. ...Read more

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Total protein 8.3, serum albumin 4.2 , serum globulin 3.8, albumin globulin ratio 1.2.. Is this abnormal?

Total protein 8.3, serum albumin 4.2 , serum globulin 3.8, albumin globulin ratio 1.2.. Is this abnormal?

Abnormal labs: It would be helpful that for the labs mentioned above. If you. Can find the normal range or reference range and list it than our answer can be more educated and helpful. The reference range does vary from one lab to another. ...Read more

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How does oral cortisol affect acth hormone and aldosterone levels?

How does oral cortisol affect acth hormone and aldosterone levels?

Poor correlation: Hi. Oral cortisol (aka hydrocortisone) does not reliably affect ACTH secretion nor aldosterone levels. That is somewhat unfortunate for those of us treated adrenal insufficiency, since determination of proper dose is based solely on clinical response, and not labs. Aldosterone is driven by the renin-angiotensin system bypassing the pituitary. UIHC is excellent, so you have great docs close at hand ...Read more

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Cortisol 14 ug dl normal?

It depends upon: When it was drawn -- time and conditions. Generally, it's a normal value -- depending........ ...Read more

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What causes high globulin, but low globulin albumin ratio?

What causes high globulin, but low globulin albumin ratio?

Liver blood tests: The liver is an amazing organ- it does many things including making proteins your body needs. Albumin is a major protein product of the liver. Chronic illness can cause that to decline- esp. if you're not eating. Globulins are other proteins usually made to fight diseases like infections- perhaps you've been fighting an illness for a few weeks/months that explain this pattern. ...Read more

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What might expln: tsh:2.475, t3:3, t4:1.1, testo.F:1.8, test.T:38 similarly fsh, lh, 17hydrox all normal -but sex hormone binding globulin elevated at 184?

What might expln: tsh:2.475, t3:3, t4:1.1, testo.F:1.8, test.T:38 similarly fsh, lh, 17hydrox all normal -but sex hormone binding globulin elevated at 184?

Need reverse T3 (liothyronine): Just commenting on the thyroid labs: i think you may have a slight hypothyroid problem, but hard to tell without complete labs. Is the T3 (liothyronine) a total or free? Also reverse T3 (liothyronine) needs to be done to know for sure. ...Read more

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Globulin level: 4.5, Albumin level: 3.9, Total Protein: 8.4, Albumin/Globulin Ratio: 0.9, AST: 68, ALT: 105. What do these levels mean?

Need med history: You need to tell us why was this test done. Did you have some complaints? Once we know your symtoms, if any, it is easier to interpret your lab results. Your liver enzymes are slightly high and so is the globulin level which can occur due to liver problems like Hepatitis. Your doctor needs to recheck these labs in another one or two months and find the cause?hepatitis? ...Read more

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Does testosterone replacement raise igf-1?

Does testosterone replacement raise igf-1?

No: It should not. They're different hormones, controlled by different influences. ...Read more

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Tiny adrenal tumor, h cortisol, h testosterone, h creatinine, h dheas, fast gluc 106. Hysterectomy, thyromegaly Will metformin reduce testosterone?

Tiny adrenal tumor, h cortisol, h testosterone, h creatinine, h dheas, fast gluc 106.   Hysterectomy, thyromegaly
Will metformin reduce testosterone?

Hormones: Metformin medicine that keeps your blood sugar under control should not have an effect on testosterone. That said, too much metformin will likely lower your testosterone. Are you checking your blood sugar regularly? Please let me know how things are going. ...Read more

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Increased aldolase, complement c3/c4 serum, sed rate, c-react. Protein, beta globulin, monocytes, bun/creatin low mcv-mch, vit d-possible causes?

Increased aldolase,  complement c3/c4 serum, sed rate, c-react. Protein, beta globulin, monocytes, bun/creatin low mcv-mch, vit d-possible causes?

Complicated: When i was doing clinical medicine, these were collectively sort of the flags for sarcoid disease but I am not saying that's the case here. This is because sarcoid is a diagnosis of exclusion so the advice is to rule out other diseases with additional diagnostic tests which can be done by a primary care physician or rheumatologist. ...Read more

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Protein Total Serum 8.7 Globulin Serum 4.20 Albumin/ Globulin Ratio 1.07 ALP 132 Urea/ CreatinineRatio 18.54 rest normal . Any worries here ?

Need more info.: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, there is no immediate concern, however, your globulin level may be higher than normal and you should discuss it with the doctor who ordered the tests. For good health - Have a diet rich in fresh vegetables, fruits, whole grains, milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Drink enough water daily, so that your urine is mostly colorless. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form. Practice safe sex. ...Read more

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Birth control upregulates sex hormone binding globulin SHBG allowing it to bind to more circulating Free Testosterone. will my levels ever be normal ?

Birth control upregulates sex hormone binding globulin SHBG allowing it to bind to more circulating Free Testosterone. will my levels ever be normal ?

Need more info: What are your levels. Are they high? What symptoms do you have? Lab numbers by themselves have very little value. One has to know the clinical setting to be able to interpret them correctly. ...Read more

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Serum iron 4umol/L Transferrin IBC 64umol/L Transferrin saturation 6% Serum ferritin assay 62ug/L Am I iron deficient? levels on 2 iron tablets /day

Serum iron 4umol/L
Transferrin IBC 64umol/L
Transferrin saturation 6%
Serum ferritin assay 62ug/L

Am I iron deficient? levels on 2 iron tablets /day

Need to evaluate: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, your results are consistent with iron deficiency. Do you have heavy periods? Do you eat a normal diet? Have you been evaluated for celiac disease? If you are not able to absorb oral iron, it may be given intravenously. For good health - Have a diet rich in fresh vegetables, fruits, whole grains, milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form. Practice safe sex. Get HPV vaccine. ...Read more

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Does growth hormone deficiency lower testosterone levels?

Does growth hormone deficiency lower testosterone levels?

No: Your pituitary controls a number of hormones including thyroid, growth, testosterone & estradiol, among others. While growth hormone deficiency won't "lower" testosterone, pituitary damage leading to growth hormone deficiency can also lead to hypogonadism or low testosterone. It's also common to have a defect in just one hormone rather than all. Traumatic brain injury is not a major concern. ...Read more

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Blood results: alt/sgpt serum level=40 iu/l, serum alkaline phosphatase=43 iu/l, serum bilirubin level=2 umol/l, serum urea level=2.3 mmol/l. Normal?

Blood results: alt/sgpt serum level=40 iu/l, serum alkaline phosphatase=43 iu/l, serum bilirubin level=2 umol/l, serum urea level=2.3 mmol/l. Normal?

Normal: It is very important to know why these were drawn in what sounds to be an otherwise healthy 19 year old. Did you expect to find something wrong? ...Read more

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Acth level in cushings?

Acth level in cushings?

High in Cushing's: Elevated. Melanocortin secretion is also high and gives rise to frequent hyperpigmentation. ...Read more