Doctor insights on:
Conversion From Epogen To Aranesp
Erythropoietin: Epogen (epoetin alfa) is a very expensive medication which can only be prescribed by a physician (usually a hematologist, oncologist, or nephrologist). Some insurance plans won't let the patient give it to themselves and instead insist that it be given in the doctor's clinic. ...Read more
Very common: As the kidneys fail the production of erythropoetin (procrit (epoetin alfa) and epogen) falls off and anemia results. With replacement anemia and transfusion are avoided late stage kidney diease patients get treated with these drugs and almost all end stage renal failure patients. These drugs do nothing for kidney disease, they just fix the anemia. ...Read more
Erthropoietin is a hormone that stimulated production of red cells. Renal failure patients are some times treated with recombinant erthropoietin.
For good health - Have a diet rich in fresh vegetables, fruits, whole grains, milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Drink enough water daily, so that your urine is mostly colorless. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form.
Practice safe sex, if you have sex. ...Read more
Wikipedia isn't bad: Http://en. Wikipedia. Org/wiki/erythropoietin.Get a more detailed answer ›
Kidney failure: Erythropoietin is commonly used in people with anemia due to kidney failure. Other uses include anemia associatid with hiv, chemotherapy and some types of bone marrow diease. It may also be used pre-surgically in certain selected patients. It has also been used improperly as a performance enhancing agent in competative sports. ...Read more
Hypoxia: This is a very complex process. The simplest answer is: hypoxia (low oxygen tension, anemia) stimulates HIF production (hopoxia-inducible factor) which then stimulates EPO release from the kidney. Another protein called VHL inhibits HIF action on EPO (negative regulator). Mutation of VHL can cause excessive EPO release, resulting in congenital erythrocytosis (a rare genetic disorder). ...Read more
If needed can take:
Erythropoietin is used for promoting red blood cells. Since premature infants can have anemia, as well as pediatric patients undergoing chemotherapy, it is a valuable tool. It has been approved by the FDA for these reasons. It has also been approved for pediatric renal disease.
I hope this helps you. I would hope that you are not having to deal with these problems but if so, I wish you well. ...Read more
Usually not: Unless the remaining kidney is not functioning well, it should be able to easily compensate for this. ...Read more
Uncertain.: Epoetin alfa & Coenzyme Q10 (ubiquinone) was the only check I was able to do in the Drugs. Com drug interaction checker. Maybe in you could be more specific about the erythropoietin. Drugs. Com drug interaction checker didn't show any known interactions between Epoetin alfa and Coenzyme Q10. ...Read more
Usually increases: Eryhtropoeitin production is increased as a response to anemia- however in certain conditions this does not happen and levels can remain flat and low. ...Read more
Generally not: Erythropoietin is associated with an increased risk of cardiovascular events, stroke and hypertensive encephalopathy. So, in general, it is not recommended for use in patients with high blood pressure, chronic renal failure, or cardiovascular disease except with extreme caution. Consult your doctor if you have heart disease and anemia, alternate therapies or dosing may be available. ...Read more