Doctor insights on:
Conversion From Epogen To Aranesp
Very common: As the kidneys fail the production of erythropoetin (procrit (epoetin alfa) and epogen) falls off and anemia results.With replacement anemia and transfusion are avoided late stage kidney diease patients get treated with these drugs and almost all end stage renal failure patients. These drugs do nothing for kidney disease, they just fix the anemia. ...Read moreSee 1 more doctor answer
Hydroxyprogesterone hexanoate is made from 16-dehydropregnenolone acetate,does it have androgenic activity?
How does muscle weakness from glucocorticoids differ from that from vita d deficiency and that from serotonin toxicity?
Weakness.: Weakness is weakness no matter the cause. That said, steroids can in some instances cause weakness via damage to type 2 muscle fibers (those that produce power). Vit d def also causes atrophy of type 2 muscle fibers which tends to be more reversible (with vit d replacement). Serotonin toxicity causes uncontrolled muscle spasms which, if severe, can cause severe muscle breakdown (type 1 & 2 fibers). ...Read more
I have anemia from ongoing hep c tx. May need procrit (epoetin alfa) injection. Any dietary advice to build up hemoglobin levels and red/white cell counts?
Why is ATP the preferred energy currency , not GTP (guanosine triphosphate), CTP or TTP? Please answer me
Do not know: There are many quirks of life on earth that cannot be explained. Why are amino acids of L form and sugars of D form only? Why are neural circuits crossed so that left side of the brain controls the right side of the body? Why don't we live longer? Why don't we have eyes on the back of the head to be able to have 360 degree vision. Ask your God! ...Read more
Impaired are: tyrosine to dopamine, tryptophan to niacin, cystathionine to cysteine. Which cofactor and vitamin is common to all three pathways? Ty
Not an easy answer: These pathways can be impaired due to a primary disorder or secondary to other conditions interfering with metabolic pathways. Until a thorough investigation has been done, it is not likely that you will find a simple solution or single co-factor that will treat your biochemical imbalances. ...Read more
For a person who is on procrit (epoetin alfa), (epoetin alfa) what is the lowest blood number one can have without taking procrit (epoetin alfa) and not causing harm or damage?
Hemoglobin 10 or 11: For patients who are anemic due to ongoing chemotherapy, Procrit (epoetin alfa) is not recommended to be given if hemoglobin is 10 or above. For patients who are anemic due to kidney failure on dialysis or not, a similar product Epogen is not recommended if hemoglobin is 11 or above. Medicare and most insurance providers have used these parameters due to "safety concerns" that higher HGB levels pose a detriment. ...Read moreSee 1 more doctor answer
Does testosterone deficiency cause anemia and reduced responsiveness to erythropoiesis-stimulating agents?
75y old(single kidney+chronic kidney disease),creatinine (~250),hemoglobin (~9.5),red cell count(3.6),Iron serum(107). Shall we use Aranesp (darbepoetin alfa) injection?
Wiki says B12 injections can cause transient drop in k levels through rapid intake of k into RBC production. Hypokalemia. T or f?
"Anecdotal": And transient. And only reported when people are severely deficient. A B12 injection in someone gravely sick from pernicious anemia causes a massive rebound in the marrow, with as much as a pound of new vital blood-forming in a few days. Why extra k is required at the time. This has been misrepresented by "pop" amateur doctors. I'm glad you're skeptical about internet distortions. Best wishes. ...Read moreSee 1 more doctor answer
Here's accurate info: Somebody's kidding you or there is a misunderstanding. Creatine kinase is an enzyme found in the blood; the reference range was determined for couch potatoes, and in my series' of athletic medical students, a majority of healthy young people have "elevated levels" just from exercising. It's also high in a few illnesses your physician knows about, but not from "nerves". ...Read more
What anticoagulant is safe in CKD b/c Apixaban cause an increase ins.cr from 1.7 to 2.1are those NOAC nephrotixic compared to warfarin in atrial fib?
Coumadin (warfarin): Does not affect kidney functionGet a more detailed answer ›
Can taking bovine colostrum increase plasma immunoglobulin levels, thereby masking an underlying immunoglobulin deficiency by altering blood tests?
Unlikely: Very thoughtful idea. Unfortunately, the bovine immunoglobins are too large to be absorbed from the intestine and would be digested by stomach and intestinal juices and enzymes. With use you would be providing body with raw materials for making your own immunoglobulins, but at a cost. Any "complete" proteins from eggs or milk could provide the same protein precursors and support good health. ...Read moreSee 1 more doctor answer
Is injecting intramuscle amino acid solution(which is used intravascular for patients with low protein)useful for building muscle in bodybuilding?
Sounds like: Torture to me. No benefit, infection risk and likely painful. ...Read more
What are the ways to cure endothelial damage from high LDL, does Nitric Oxide supplementation help in the healing?
When a male uses a DHT blocker does that mean that instead of excess testosterone converting to DHT it will convert to estrogen? Is blocking DHT safe?
Yes (maybe): As you noted, 5ARIs (alpha reductase inhibitors) block conversion of Testosterone into Dihydrotestosterone. However, as a consequence, you might convert T into Estradiol (estrogen). This is real concern w/potential side effects such as gynecomastia, loss of libido, erectile dysfunction listed in small print for drug. There have also been reports of infertility. Only u can decide if benefit > risk ...Read moreSee 1 more doctor answer
Consider medical ID jewel. How to abbreviate Anaphylactic shock/allergy to tranexamic acid (transamin) & Vit K in 20 chracter? What is most important?
What happened: Just get "MEDICATION ALLERGIES". Have a paper explaining it on you, and let your friends / neighbors know. Believe it or now, it IS possible to get anaphylactic reactions to some of today's intravenous vitamin K preparations. I'd urge you to get with an allergist to sort out exactly what happened to you; both meds were likely administered during a crisis and who-knows-what else may be operating. ...Read more