Doctor insights on:
Congenital Insensitivity To Pain With Anhidrosis Statistics
Very rare: A genetic mutation that leads to increase risk of both heat injury due to inability to sweat and cool oneself and the lack of protective reflexes due to pain. I reviewed these article that may help you with more of your questions http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3371914/ http://ghr.nlm.nih.gov/condition/congenital-insensitivity-to-pain. ...Read more
Pain: Is a rare condition in which the person does not feel physical pain and has a genetic predisposition . Patients can still feel if somebody is touching them and they have no physical abnormalities . Consult with a neurologist for more information ...Read more
2 types:: There are generally 2 types of non-response exhibited in cip: 1. Insensitivity to pain: painful stimulus is not even perceived: a patient cannot describe the intensity or type of pain. 2. Indifference to pain: a patient can perceive the stimulus, but lacks an appropriate response: they will not flinch or withdraw when exposed to pain. Cognition and sensation are normal! ...Read more
Gene mutation: It is a mutation of a gene which is part of a chromosome. ...Read more
What is the difference between congenital insensitivity to pain & congenital indifference to pain?
Difference: An insensitivity would mean that the person does not actually feel the pain. An indifference would mean that the person can feel pain, but doesn't seem to care. They could be due to several factors but can be dangerous if the person doesn't respond appropriately to pain. Pain is a warning that something is wrong! ...Read more
Need ped cardiology help finding out the statistics of congenital heart defects & follow up surgery?
Intolerance or more?: Gluten intolerance (about 10% of people) may cause bloating, diarrhea, nonspecific complaints. Celiac disease, among its many manifestations may result in diarrhea. In the latter, exposure of intestine to gluten causes inflammation of affected gut lining, with a decrease in absorptive surface of that gut, & resulting malabsorption of food--best & most enduring fix being to avoid eating gluten. ...Read moreSee 1 more doctor answer
Avoid gluten: 6 percent of the u.S population has gluten sensitivity. 1 percent has celiac. There is no objective test to prove gluten sensitivity. If one cuts out gluten, they should feel fine if he or she is gluten sensitive. Celiac on the other hand can be confirmed by endoscopy and/or blood tests. If you have any suspicion of this you should see a doctor. ...Read more
No: If you were born without sweat glands, we aren't going to make your grow them. We cure infectious and surgical diseases; most other disease we manage. If this is a newborn, a check for fabry's might be in order. New anhidrosis over an area may be acquired, famously in nerve injury or compromise by tumor. Athletes with anhidrosis may have friends throw cold water on them. Thanks for asking. ...Read more
Avoidance strategy: FODMAPs stands for Fermentable Oligosaccharides, Disaccharides, Monosaccharides and Polyols. These short chain carbohydrates are incompletely absorbed in the GI tract and can be easily fermented by gut bacteria. These sugars exert an osmotic effect increased fluid in the large bowel. In turn cause IBS sx like gas pain and diarrhea. Address intestinal bacterial overgrowth with probiotics .Avoid ...Read more
I have anhidrosis. It has come and gone after 7 mo and 2 years later 12 months. I am an athelete and it is debilitating.?
Treat the root cause: Anhidrosis is a challenge for an athlete because of the risk of overheating while participating in your sport. Chose how and when you compete carefully. Wear appropriate clothing. If possible, workout in climate controlled areas. To treat it, one must define why it is happening. Possible causes include malfunctioning nerves, medications, diabetes, etc. It is best to be seen by your doctor. ...Read more
Genetic condition: In androgen insensitivity syndrome the patient is genetically male (i.e. Has both an x and a y chromosome), but the tissues do not respond normally to male hormones in the course of development, so the external body appearance is closer to that of a female. ...Read moreSee 2 more doctor answers
My daughter has conginatal insensitivity to pain..Cipa .. What is the possibility of recovering from cipa. She is 2yr old now.
CIPA: Since the condition is due to a genetic mutation the chance of her recovering are practically nil. ...Read more
Is there anyway to restore vaginal insensitivity? It is impossible for penetration, during sex there is no feeling or sensation like a numbness
Vaginal sensation: Many things may contribute to your experience, and the best help depends on the most likely causes. The most powerful sexual sensations usually focus most on the clitoris and initial parts of the vagina. I suggest starting with an exam by a compassionate gynecologist.Experiencing previous trauma can affect physical sensation. Help for this is possible through psychiatrists and other professionals. ...Read moreSee 1 more doctor answer
No: Androgen insensitivity means that the receptors for testosterone type of hormones (t) cannot respond to t stimulation. In more severe cases infants with xy chromosomes (typically male) may develop female genitalia during fetal development because if this. They are likely to be raised as females with a diagnosis only coming after they don't get sexual hair or periods. ...Read moreSee 2 more doctor answers
XY baby is a girl: Without testosterone (t), all babies develop as girls. So a child with 1 x & 1 y chromosome, who would normally be a boy, would develop as a girl if no t was present. In androgen insensitivity syndrome, the t is there, but the cells are insensitive to it, and don't respond, so it's as if the t was not there at all. So an xy genetic boy baby is born looking like a normal healthy baby girl. ...Read moreSee 1 more doctor answer
It's complicated!: Patient born with poor testosterone action, so a male patient is female-appearing, and is usually raised by the family as a female. Big changes at puberty, however, with breast development, but also enlargement of the clitoris which can be quite alarming, and other male sex characteristics. Removal of the testicles can preserve female body identity and appearance in this disorder. ...Read moreSee 1 more doctor answer
AIS: Defects in androgen receptor function cause a disorder of sex development in which 46,XY individuals do not virilize normally, despite the presence of bilateral testes and serum testosterone concentrations within or above the normal male range. The presentation varies from Complete or Partial Androgen Insensitivity Syndrome with variable phenotypes. ...Read more
Puberty: Usually, xy babies are born looking like healthy baby girls. During puberty, however, they don't develop secondary sexual characteristics that require testosterone such as axillary or pubic hair. Since estrogen is present, they grow breasts and develop a thin waist with larger hips, but don't have periods since they lack a uterus. Most often, lack of periods by age 15 or 16 leads to the diagnosis. ...Read moreSee 1 more doctor answer
A.I.S. Quick Answer: Androgen insensitivity syndrome (ais) is when a person who is genetically male (who has one x and one y chromosome) is resistant to male hormones (called androgens). As a result, the person has some or all of the physical traits of a woman, but the genetic makeup of a man. The effect of androgen insensitivity is potentially quite profound. ...Read moreSee 1 more doctor answer
It's complicated!: Androgen insensitivity syndrome is an extremely complex disorder due to failure of development in the genital area, with sometimes dramatic changes at puberty. Due to complex issues with gender, anatomy, and subsequent treatment, questions about this disorder should be addressed with a pediatric endocrinology consultation. ...Read more
Can be Complicated: Complete ais isn't usually discovered until a girl fails to menstruate & has little or no pubic/underarm hair. No uterus, but those w/cais have intraabdominal testes which are removed because of cancer potential. Female by default as they can't respond to androgens in utero. Partial ai: babies are born with variable degrees of virilization. Assigning sex can be complicated. ...Read moreSee 1 more doctor answer