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Doctor insights on: Congenital Hepatic Fibrosis

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What's it mean to have hepatic fibrosis?

What's it mean to have hepatic fibrosis?

Fibrosis = scarring: Inflammation of the liver, as almost anywhere else in the body, often heals with scarring. Lose enough functioning liver cells to scarring & you get cirrhosis. A fibrosis score is typically calculated during liver biopsy (& some fancier liver imagings) to calculate how much damage a chronically inflammed liver has sustained, & its risk of failing /decompensating. Then you need a liver transplant. ...Read more

Hepatic (Definition)

Hepatic refers to something that is ...Read more


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What are the tests for hepatic fibrosis?

HepaScore: If not liver biopsy, alpha2 macro globulin increase; a lipoprotein a1 decrease, ggt, bilirubin, hyaluronic enzyme immunoassay; sex and age factor in as well. ...Read more

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What are the symptoms of hepatic fibrosis?

What are the symptoms of hepatic fibrosis?

None: Fibrosis is scarring as a result of inflammation and tissue damage. Eventually the scarring isolates pockets of hepatocytes (liver cells) so that they can no longer function appropriately. This is cirrhosis, and that creates problems resulting in symptoms. ...Read more

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Liver biopsy = hepatic parenchyma showing moderate to severe chronic hepatitis w/bridging fibrosis &focal changes of early micronodular cirrhosis. Grade 3-4 stage 3-4. Can thyroid cause this? Or what?

Liver biopsy = hepatic parenchyma showing moderate to severe chronic hepatitis w/bridging fibrosis &focal changes of early micronodular cirrhosis. Grade 3-4 stage 3-4. Can thyroid cause this? Or what?

No: thyroid problems do not cause cirrhosis. you may have an autoimmune hepatitis leading to cirrhosis, which could be associated with thyroid disease. There are many causes of cirrhosis, ask your doctor to test you, as most can be checked with a blood test. ...Read more

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How can cystic fibrosis affect p.I.E.S development?

How can cystic fibrosis affect p.I.E.S development?

Certainly: Cystic Fibrosis (CF) most common life-limiting genetic disorder of Caucasians, affecting approximately 30K people in the US.A, impacting mainly respiratory function. In recent years patients symptoms better controlled by genetic findings and better medications.Emotional & phys. development depend on severity, time in hospital, complications.Morb. & mort.factors afect emotional,cognitive behavior. ...Read more

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Can someone be diagnose with cystic fibrosis in their 40's?

Can someone be diagnose with cystic fibrosis in their 40's?

As a carrier: Genetic carrier testing: more than 10 million americans are symptomless carriers of the defective CF gene. This blood test can help detect carriers, who could pass CF onto their children. To have cystic fibrosis, a child must inherit one copy of the defective CF gene from each parent. ...Read more

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I have symptoms of cystic fibrosis. Is it possible to start show the symptoms in my 30's?

Yes: Yes it is possible. Presentation of cystic fibrosis varies greatly, and it is possible, depending on your specific mutation (and other factors) to present at a later age. In order to prevent late diagnoses, all states now have a newborn screen in place for cystic fibrosis. ...Read more

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I have family members with cystic fibrosis. Is it possible to start show the symptoms in my 20's?

I have family members with cystic fibrosis. Is it possible to start show the symptoms in my 20's?

Yes: However, usually an adult who is diagnosed so late has usually had chronic problems with cough and "pneumonias". That said i've diagnosed a new case in a 38 year old woman. ...Read more

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What are the chances of a child getting cystic fibrosis among the different racial groups in the u.S.?

What are the chances of a child getting cystic fibrosis among the different racial groups in the u.S.?

Overall 1/3700: Acording to the CF foundation: the overall birth prevalence is 1/3700 . It can occur in any race, however the greatest incidence is in caucasians of northern european descent, being 1/2500. The other major groups affected are hispanics 1/13500, african americans 1/15000. More than 10 million of us carry one part of the defective gene, but to have the disease you must have a copy from both parents. ...Read more

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What is residual fibrosis? Is it a severe case?

What is residual fibrosis? Is it a severe case?

Fancy name...: A description for a little bit of scarring following an illness from which you've recovered. I'm sorry the lingo threw you for a loop. Chat with your physician about this if it popped up on a report, and good luck. ...Read more

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I have a minimal right aprical fibrosis. What does that mean?

I have a minimal right aprical fibrosis. What does that mean?

It means: there is an area of scarring in the upper part of your right lung. It could be due to many causes, such as prior infection, but if it is an incidental finding and you are otherwise asymptomatic it may be of no concern. Talk to your doc about the results. ...Read more

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What is vaginal fibrosis and how do you cure it?

What is vaginal fibrosis and how do you cure it?

Vaginal fibrosis: You can think of vaginal fibrosis as bad scar tissue in the vagina. It typically is the side effect of radiation therapy for gynecologic cancers. The vagina looses its elasticity and can shrink. ...Read more

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Hi doctors, can you tell me what is retropertineal fibrosis?

Hi doctors, can you tell me what is retropertineal fibrosis?

Retroperitoneal Fibr: Retroperitoneal fibrosis is a rare disease, often idiopathic, but drugs, infections malignancies, prior surgeries, radiation therapy, smoking, and asbestos exposure have been implicated. . It is characterized by the presence of inflammatory and fibrous retroperitoneal tissue that often encases the ureters & other abdominal organs. Symptoms include back or flank pain, and decreased kidney function ...Read more

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Can you die of cystic fibrosis?

Yes but: Yes but with early diagnosis and regular care and adherence to prescribed therapy by a pediatric pulmonologist the long term survival has improved greatly in the past two decades. ...Read more

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What is risk of cystic fibrosis?

What is risk of cystic fibrosis?

Depends on genes: The risk of acquiring cystic fibrosis (CF) depends on whether the parents of a child are carriers for the gene. It is estimated that about 1 in 20 americans are carriers of the CF gene. In order for a child to acquire the disease, both parents must be carriers. If both parents are carriers, there is then a 25% chance that the child will acquire the disease. ...Read more

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Can you die from cystic fibrosis?

Yes.: Although the complications of cystic fibrosis are treatable, and although the available treatments are helpful, the disorder shortens the normal life expectancy. ...Read more

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What are symptoms of cystic fibrosis?

Cough, poor growth: Common symptoms of cystic fibrosis include cough, wheeze, recurrent lung infections, poor growth, foul smelling stools, salty sweat, clubbing, and rectal prolapse. The more symptoms the greater the chance of having cystic fibrosis. Most infants today are diagnosed by newborn screening for CF before they develop any symptoms and early therapy can minimize disease symptoms. ...Read more

Dr. Marvin Ott
8 doctors shared insights

Hepatic Fibrosis (Definition)

There is excessive connective ...Read more