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Doctor insights on: Congenital Diabetes Insipidus

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Dr. Luis Gonzalez-mendoza
251 doctors shared insights

Diabetes Insipidus (Definition)

A condition in which your pituitary gland does not make the ADH hormone, and you have to drink and urinate constantly. Many with this condition carry water with them at all ...Read more


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Could chiari malformation cause pituitary problems or diabetes insipidus?

Could chiari malformation cause pituitary problems or diabetes insipidus?

Very unusual: 7 cases of hypopituitarism all having a history of breech delivery, asphyxia at birth, and syringomyelia. A small pituitary gland was found on MRI or CT in six cases, invisible pituitary stalk on MRI in five cases, and type 1 Arnold-Chiari malformation in six cases. A constellation of these abnormalities best explained by traction of brain and spinal cord.Not usually with uncomplicated Chiari 1. ...Read more

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How are diabetes insipidus and diabetes mellitus different?

How are diabetes insipidus and diabetes mellitus different?

Very different: Diabetes mellitus is the typical "diabetes" that we are familiar with. It's caused by an Insulin problem (too little or just not working well (resistance)) causing elevation in blood sugar. Diabetes insipidus is a water problem characterized by lots of urination and high sodium level. It's caused by an ADH (vasopressin) (antidiuretic hormone) problem (too little or just not working well). ...Read more

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What is diabetes insipidus?

What is diabetes insipidus?

Two types: Either antidiuretic hormone (ADH (vasopressin)) is not being made in the posterior part of the pituitary or ADH (vasopressin) is being made, but the kidney lacks the receptor to which ADH (vasopressin) is bound in order to work to preserve water from leaving the body in excess. ...Read more

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Is nephrogenic diabetes insipidus similiar to children's diabetes or not?

Is nephrogenic diabetes insipidus similiar to children's diabetes or not?

Imprecise question: Diabetes insipitus is decreased production or effect of vasopressin- nephrogenic is where it's effect reduced because of a kidney issue diabetes mellitus is a high sugar problem due to immune destruction of cells making Insulin in pancreas they are different disease states. ...Read more

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Possible complications of diabetes mellitus?

Possible complications of diabetes mellitus?

Many: Diabetes is a multi system disease. Therefore it can affect almost any part of your body. You name, i can tie a potential diabetic complication. I'll quickly go head to toe. 1: brain - stroke 2: eyes: blindness 3: heart: coronary disease 4: gi: gastroparesis (slowing) 5: genito/urinary: erectile dysfunction 6: legs: poor circulation this is just a small sampling! ...Read more

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How is gestational diabetes mellitus diagnosed?

How is gestational diabetes mellitus diagnosed?

High blood sugar: Pregnancy can make a woman's body resistant to Insulin (similar to type 2 diabetes). If she was not diabetic before being pregnant and meets one of several sets of criteria for diabetes after becoming pregnant, then she may have gestational diabetes. This gives her an increased risk of developing diabetes after delivering the baby. Usually found during routine glucose tolerance testing. Thanks! ...Read more

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Is gestational diabetes hereditary?

Is gestational diabetes hereditary?

Yes, but partially: Gestational diabetes, which is often a precursor to type 2 diabetes, has a strong hereditary genetic component. The tendency for the body to be insulin-resistant and insulin-deficient (leading to high sugars) are often transmitted in the genetic make-up. However, gestational diabetes is also strongly related to other non-hereditary factors like age, weight, physical activity levels, and diet habits. ...Read more

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Pathophysiology of diabetes mellitus in pregnancy?

Pathophysiology of diabetes mellitus in pregnancy?

Glucose intolerance: The short paragraph here doesn't give me alot to explain this, but basically pregnancy is a relatively glucose resistant state and the more times you are pregnant, the more likely you get gestational diabetes. There are alterations in Insulin levels and Insulin resistance during the pregnancy. The typical american diet of high sugar processed foods doesn't help. ...Read more

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Could diabetes insipidus lead to seizures?

Could diabetes insipidus lead to seizures?

Seizures and DI: DI could be related to seizures, at least because there are changes in electrolytes in cases of DI, and electrolyte abnormalities often cause seizures. Electrolytes include sodium, potassium and calcium. ...Read more

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How does diabetes mellitus causes placental insufficiency ?

How does diabetes mellitus causes placental insufficiency ?

Blood flow: Diabetes is a glucose control disorder that affects blood vessels. If diabetes is well controlled then the injury to blood vessels is negligible. When blood vessels are narrowed or compromised-then the fetus receives less blood flow and nutrients which may be associated with newborn problems. ...Read more

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Why there is hyperlipidemia in diabetes mellitus?

Why there is hyperlipidemia in diabetes mellitus?

Hyperlipidemia: Is essentially high cholesterol. Diabetes is a distinct disorder. Some folks have one or the other and you appear to have both. Both need to be treated. Please see your doc who can help you. Peace and good health. ...Read more

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Is diabetes type II diabetes curable?

Is diabetes type II diabetes curable?

Yes and No.: Diabetes is genetic. We can treat the disease and then management will take care of the rest. Proper diet, exercise, management of stress all play a role. The younger you are and healthier you keep your ideal weight for age and height, the better chances you have to become "diet" regulated versus "medicine" regulated. Talk with your primary doc or meet with an endocrinologist. ...Read more

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Gestational diabetes mellitus--what are risk factors or causes?

Weight/Family Hist.: Obesity is a major risk for any diabetes. The other factor is genetics. There are many women of asian descent who have a normal weight (and body mass index), but develop gestational or regular diabetes. Obesity is one that people can modify though. ...Read more

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What is diabetes mellitus?

What is diabetes mellitus?

"Sugar diabetes": Diabetes mellitus is the medical term for the common form of diabetes. Diabetes is a word which originally meant "flow like a siphon" or "frequent urination" and mellitus means "sweet". This is the most common form of diabetes in the us i.e. Diabetes mellitus type 2.This is from Insulin resistance which occurs mostly from obesity. ...Read more

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Is gestational diabetes a disease?

Is gestational diabetes a disease?

Yes.: Gestational diabetes is when during pregnancy, a woman is unable to produce enough Insulin to regulate her body's blood sugar. Gestational diabetes should be managed carefully to reduce health risks to the woman and her fetus. Also, there is higher risk of developing diabetes in the future. ...Read more

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What do I do if I have diabetes insipidus?

Follow doc's advise: You need to find out the cause so you can be treated appropriately. Often time, diabetes insipidus is just a symptom, not the cause. The hormone involved is ADH (vasopressin) (antidiuretic hormone). If the cause is in the brain, treatment is to give back ADH (vasopressin) (ddavp) either in nasal spray or pill. If the problem is at the kidney, treatment is antiinflammatory (indomethacin) and diuretics (hctz and amiloride). ...Read more

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Diabetes insipidus == what are the symptoms?

Diabetes insipidus == what are the symptoms?

Symptoms of D Insipi: Symptoms of diabetes insipidus are excessive urination and extreme thorst especialy of cold water sometimes ice and ice water.Extreme urination continues throghout the day and the night adults remain healthy as long as enough water is consumed to offset the urinary loss . In children it interfere with eating and weight gain and growth.They present with fever, vomiting and diarrhea. ...Read more

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What are the symptoms of diabetes insipidus?

What are the symptoms of diabetes insipidus?

Peeing all the time!: Diabetes insipidus (or di) is caused by either a lack of or a resistance to the hormone in your body (antidiuretic hormone) which normally allows your body to concentrate urine (so that you make less of it). Without this hormone, you produce large volumes or urine, and often patients present with excess thirst because they are on the verge of getting dehydrated from all the urine output. ...Read more

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What are the complications of diabetes insipidus?

What are the complications of diabetes insipidus?

Many: Depends on the severity of the disorder, you can get dehydrated or have electrolyte imbalances. The physical consequences of di are: dry mouth, low blood pressure, muscle weakness, sunken eyes, weight loss, fatigue, headache, muscle spasms... ...Read more

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What kind of condition is diabetes insipidus (d.I.)?

What kind of condition is diabetes insipidus (d.I.)?

Missing ADH (vasopressin): Anti diuretic hormone helps concentrate the urine to keep the body's sodium and water levels balanced. If the brain does not make enough ADH (vasopressin) or of the kidney ignores the adh, (vasopressin) a person can urinate too much dilute urine, becoming hypernatremic (high sodium) and dehydrated. Can be genetic, due to head trauma, brain tumor, infection, anorexia, idiopathic. ...Read more

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How does diabetes insipidus affect lifespan?

How does diabetes insipidus affect lifespan?

Little: Diabetes insipidus is caused by the inability of the kidneys to conserve water, which leads to frequent urination and pronounced thirst.The outcome depends on the underlying disorder. If treated, diabetes insipidus does not cause severe problems or reduce life expectancy. ...Read more

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Is diabetes insipidus is temporary or curable?

It depends.: Sometimes, diabetes insipidus (inability for the body to hold onto water due to the lack of or inaction of anti-diuretic hormone (adh)) is temporary after brain surgery. If permanent, usually due to a pituitary or kidney problem, it is not usually curable but can be easily treated especially if dealing with an ADH (vasopressin) deficiency. ...Read more

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Can you tell me how hypernatremia occur in diabetes insipidus?

Can you tell me how hypernatremia occur in diabetes insipidus?

ADH (vasopressin): Hypernatremia occurs in diabetes insipidus secondary due to the lack of anti diuretic hormone (ADH) effect in the kidney, resulting in decreased free water absorption thus creating a higher sodium. ...Read more

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Can you tell me what the epidemiology of diabetes insipidus is?

Can you tell me what the epidemiology of diabetes insipidus is?

Rare disorder: Diabetes insipidus (di) is a rare disorder in which the kidneys cannot concentrate urine, thereby causing excessive loss of water from the body and dehydration. It can result from a problem of the pituitary gland, or from a defect in the kidneys. However, most people who think they have di are actually excessive fluid drinkers, and urinate a lot because they drink a lot. ...Read more

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What is the assessment and diagnostic finding of diabetes insipidus?

Hickey-Hare test: Inability to concentrate urine with restriction of fluid intake must be done by md, with careful observation/ testing urine and blood. ...Read more

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What's the most effective way to treat child with diabetes insipidus?

What's the most effective way to treat child with diabetes insipidus?

Depends: The answer depends on the cause of the diabetes insipidus. Often time, diabetes insipidus is just a symptom, not the cause. The hormone involved is ADH (vasopressin) (antidiuretic hormone). If the cause is in the brain, treatment is to give back ADH (vasopressin) (ddavp) either in nasal spray or pill. If the problem is at the kidney, treatment is antiinflammatory (indomethacin) and diuretics (hctz and amiloride). ...Read more

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Is there any negative effect of a diabetes insipidus person to her/his fertilizaition?

Is there any negative effect of a diabetes insipidus person to her/his fertilizaition?

Could be: Oftentimes patients with di have accompanying anterior pituitary hormone deficiencies. This is something regularly followed by an endocrinologist in patients who have di. ...Read more

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What can I do if my two year old has just been diagnosed with diabetes insipidus any tips?

What can I do if my two year old has just been diagnosed with diabetes insipidus any tips?

Electrolyte problem: Diabetes insipidus occurs due to either abnormality in hormone secretion from the brain or kidney not responding to this hormone. High blood sodium levels is one of the common and serious electrolyte problem. Being two year old, the child may not be able to express the thirst or get access to water when the sodium level is high. It is crucial for the parents to carefully monitor them. ...Read more

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My two-year-old has just been diagnosed with diabetes insipidus. What can we do to make the adjustment easier?

My two-year-old has just been diagnosed with diabetes insipidus. What can we do to make the adjustment easier?

DDAVP (desmopressin) & Symptoms: That your child is getting treatment is the best way to become adjusted. Now your toddler will be much better able to sleep through the night and be less cranky as the constant thirst will be quenched! watch for breakthrough so you know when the DDAVP (desmopressin) is wearing off. Your peds endo will discuss with you when to restrict fluids. Does your child have other pituitary hormone deficiency? Cause of di? ...Read more

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Why are thiazide diuretics used in diabetes insipidus?

Paradox: Thiazides paradoxically reduce the amount of urine the kidneys produce in the nephrogenic form of di. Thiazides are not used in the central form. ...Read more

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What is diabetes insipidus?

Two types: Either antidiuretic hormone (ADH (vasopressin)) is not being made in the posterior part of the pituitary or ADH (vasopressin) is being made, but the kidney lacks the receptor to which ADH (vasopressin) is bound in order to work to preserve water from leaving the body in excess. ...Read more

Dr. Quang Nguyen
3,343 doctors shared insights

Diabetes (Definition)

A group of diseases that result in too much sugar in the ...Read more