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Doctor insights on: Congenital Adrenal Hyperplasia And Pregnancy

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Who has congenital adrenal hyperplasia?

Who has congenital adrenal hyperplasia?

Enzyme deficiency: Deficiency of 21 hydroxylase enzyme needed for synthesis of gluco- and mineralo-corticoids causes excessive production of sex hormones, mainly male sex hormones. The result is endocrine disturbance in both boys and girls and virilization in girls. ...Read more

Dr. Lois Freisleben-Cook
4 Doctors shared insights

Pregnancy (Definition)

When your due date arrives, you will be more than ready to have your baby! Most women deliver the baby somewhere between 37 and 42 weeks. According to the American College of Obstetricians and Gynecologists, only 5% of babies arrive on the exact due date. Approximately 7% of babies are not delivered by 42 weeks, and when that happens, it is referred to ...Read more


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What sort of disease is congenital adrenal hyperplasia?

What sort of disease is congenital adrenal hyperplasia?

Missing enzyme: There are different types. They all involve a deficiency of an enzyme needed in cortisol production. Since the pituitary senses there isn't enough cortisol, it keeps trying to make the adrenals make cortisol. But because that enzyme is missing, the building blocks of cortisol build up. These substances get turned into androgens - male hormones - and cause abnormalities in sexual development. ...Read more

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What are the symptoms of congenital adrenal hyperplasia?

What are the symptoms of congenital adrenal hyperplasia?

Classic or non?: Classic cah is diagnosed mostly on newborn screening. It results from a block in the synthesis of cortisol and usually also aldosterone. Females will often have ambiguous genitalia. Males don't look different. Permanent replacement with Hydrocortisone & Fludrocortisone (may not need past childhood) are needed for sustaining life and salt balance. Pediatric endocrinologists follow very closely. ...Read more

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What are symptoms of congenital adrenal hyperplasia in girls?

What are symptoms of congenital adrenal hyperplasia in girls?

It varies: Persons with the most common form of congenital adrenal hyperplasia (cah) have a predisposition to make extra testosterone. For girls can manifest as genitalia that is "masculinized" before birth and therefore "ambiguous" at birth. Some girls can also have "salt wasting". Girls can also have somewhat masculinized behaviors. Testosterone levels can be lowered by therapy. Www. Caresfoundation. Org. ...Read more

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Are there good alternative therapies for congenital adrenal hyperplasia?

Are there good alternative therapies for congenital adrenal hyperplasia?

Yes: There are many different types of cah. They cannot be cured - but the side effects of each - hyper or hypotension, hirsutism or virilization, etc can all be controlled by blocking the over or underactivity of the pathway steroids leading to cortisol, aldosterone and sex hormone production. ...Read more

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Congenital adrenal hyperplasia -non classical kind, what are some remedies to help with side effects of disease and medicine like steroids?

Congenital adrenal hyperplasia -non classical kind, what are some remedies to help with side effects of disease and medicine like steroids?

Adrenal hyperplasia: The commonest type of congenital adrenal hyperplasia is caused by deficiency of 21 hydroxylase, classical type presents at birth, but non classical may present later in early childhood or during puberty.It is difficult to answer all about it, but some salt depleted patients need to be on steroids and the patints need to be monotored for other defects, it should be trated by a pediatric endocrinologist. ...Read more

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What are the similarities of pcos and non-classical congenital adrenal hyperplasia?

What are the similarities of pcos and non-classical congenital adrenal hyperplasia?

Many similarities: Women with pcos or non-classical cah can have essentially identical symptoms: irregular periods, hirsutism, even virilization, infertility, acne. Both usually have features of metabolic syndrome/insulin resistance. Non-classical cah can have precocious puberty. The test to distinguish the two is a baseline and acth stimulated 17-oh progesterone. An endocrinologist is needed for this situation. ...Read more

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What is congenital adrenal hyperplasia?

What is congenital adrenal hyperplasia?

Enzyme defeciency: This disease results from deficiency of an enzyme, 21 hydroxylase, that is essential for synthesis of adrenal hormones. Block in the synthesis of glucoroticoids causes excess production of male sex hormones. See this site for more information. Http://www. Ncbi. Nlm. Nih. Gov/pubmedhealth/pmh0001448/. ...Read more

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What is the definition or description of: congenital adrenal hyperplasia?

What is the definition or description of: congenital adrenal hyperplasia?

See below: It is a collection of genetic conditions that limit your adrenal glands' ability to make certain vital hormones. In most cases of congenital adrenal hyperplasia, the adrenal glands don't produce enough cortisol. The production of two other classes of hormones also may be affected, including mineralocorticoids (for example, aldosterone) and androgens (for example, testosterone). ...Read more

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How do you prevent congenital adrenal hyperplasia?

Genetic testing: Congenital adrenal hyprplasis is an inherited disorder. Genetic screening can detect persons with the abnormal gene. Prenatal diagnosis can be made. Please consult this site for more information. Http://www. Nlm. Nih. Gov/medlineplus/ency/article/000411.htm. ...Read more

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How to treat congenital adrenal hyperplasia quickly?

? Quickly?: The diagnosis implys a genetic abnormality that will last a lifetime. It can be managed over time with the aid of metabolic disease specialists working in conjunction with your local source of health care. Daily medication & scheduled followup tests and exams will gauge the progress. ...Read more

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How to treat non-classical congenital adrenal hyperplasia?

How to treat non-classical congenital adrenal hyperplasia?

Male or Female?: This would depend on the age and sex of the patient in addition to the degree of severity. If cortisol response is normal and a male is affected, often times steroid suppression is stopped after puberty. This is more complicated in females who may otherwise suffer from irregular periods, hirsutism, recalcitrant acne. They may need treatment through adulthood. Please discuss with endocrinologist. ...Read more

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Can congenital adrenal hyperplasia affect a persons period?

Can congenital adrenal hyperplasia affect a persons period?

Cong adrenal hyper: Yes. See your physician. Wikipedia and uptodate. Com are good reads for this.
There are several kinds of this as well. ...Read more

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Can late onset congenital adrenal hyperplasia present itself with hyper pigmentation?

Can late onset congenital adrenal hyperplasia present itself with hyper pigmentation?

Addison's disease: Your history says you have addison's disease (adrenal insufficiency), which is not the same as congenital adrenal hyperplasia. Addison's disease can definitely present with darkening of the skin. Other symptoms can be found here: http://www. Mayoclinic. Com/health/addisons-disease/ds00361/dsection=symptoms. ...Read more

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Can late onset congenital adrenal hyperplasia be confused with addison's or have both?

Can late onset congenital adrenal hyperplasia be confused with addison's or have both?

Yes and no: Both can present with low blood sodium and high potassium and increased pigmentation, but further testing can separate the diagnosis. Addison's by itself in children is very rare. ...Read more

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Does a male of 35 yo still need to take cortisone for congenital adrenal hyperplasia since age 5 yo?

Maybe not: You need to see an adult endocrinologist. After 30 years of steroid hormone suppression it is no easy task to be weaned. However, weaning is dependent upon the type of cah you have and the likelihood that you may or may not develop adrenal rest tumors. Genetic testing may help here also. ...Read more

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I take 2mg Prednisolone am can I reduce this to 1mg am? I have congenital adrenal hyperplasia. I used to take 2mg on 2mg am

I take 2mg Prednisolone am can I reduce this to 1mg am? I have congenital adrenal hyperplasia. I used to take 2mg on 2mg am

Ask your doctor: Do not adjust your dose of Prednisolone without discussing it with your doctor. The effects of lowering the medication too quickly to making your levels too low can make you very sick. ...Read more

Dr. Vered Lewy-Weiss
66 Doctors shared insights

Congenital Adrenal Hyperplasia (Definition)

A collection of genetic conditions that limit your adrenal glands' ability to ...Read more