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Doctor insights on: Congenital Adrenal Hyperplasia 21 Hydroxylase Deficiency

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Dr. Vered Lewy-Weiss
68 doctors shared insights

Congenital Adrenal Hyperplasia (Definition)

A collection of genetic conditions that limit the adrenal glands' ability to ...Read more


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Thyroid u/s rl 2.2x1.5x6.1, ll 1.8x1.1x5.1. Mildly heterogeneous exhotexture.T4free 1.3 t3total 94 TSH .63. Having many thyroid symptoms.Thyroid prob?

Thyroid u/s rl 2.2x1.5x6.1, ll 1.8x1.1x5.1. Mildly heterogeneous exhotexture.T4free 1.3 t3total 94 TSH .63. Having many thyroid symptoms.Thyroid prob?

Probably not thyroid: Nodule does not appear autonomous ( doing its own thing) TSH still normal. No sptoms related to normal thyroid function. Sptoms usually come from an underlying autoimmune cponent. ...Read more

Dr. Le Wang Dr. Wang
1 doctor agreed:
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Can pernicious anemia or severe vitamin B12 deficiency cause chronic non-specific duodenitis??

Dr. Le Wang Dr. Wang
1 doctor agreed:
Can pernicious anemia or severe vitamin B12 deficiency cause chronic non-specific duodenitis??

Not clear: No clear evidence for the causal-effect relationship between the two. PA is an autoimmue-mediated destruction of parietal cells in stomach, resuling in impairmnent of B12 absorption. Certainly it is possible that pernicious anemia may co-exist or exacerbate duodenitis via immune process or loss of balance in duodenal fluid, or anemia. But the causal-effect relationship is not well established. ...Read more

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Why there's hirsutism in cushing's syndrome?

Why there's hirsutism in cushing's syndrome?

Adrenal androgens: When the adrenals are stimulated, they make cortisol, but also androgens, like DHEA-S, which causes hirsutism in women. ...Read more

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2 early MC, heartbeat seen 2nd case, no live birth, turner's synd in fetus 2nd case, karyotyping & immunological tests normal. Way fwd? More tests?

2 early MC, heartbeat seen 2nd case, no live birth, turner's synd in fetus 2nd case, karyotyping & immunological tests normal. Way fwd? More tests?

Maternal fetal medicine: specialist is what you need with your high risk pregnancies, if you don't have one available in your area please seek advice in a teaching hospital ...Read more

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2001 Hysterctomy. 5.5x3.8x4.8cm mildly complex cyst w/in rt. ovary, total size of ovary 6.0,single thick avascular curvinlear septation.3.3 simple cyst on lft, Age 49. Calcium,ser-10.3; Fsh,133.6

2001 Hysterctomy.  5.5x3.8x4.8cm mildly complex cyst w/in rt. ovary, total size of ovary 6.0,single thick avascular curvinlear septation.3.3 simple cyst on lft, Age 49.  Calcium,ser-10.3; Fsh,133.6

Talk to your doctor: The size of your right ovary is about twice the size of a normal ovary and likely most of that is taken up by the cyst. The presence of a thick septation suggests the possibility of more than just a simple cyst but does not confirm anything. Your labs don't really confirm anything and you may need more imaging. Your doc may want a Ca125 test. You need to have a frank conversation with him/her. ...Read more

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Can celiac disease cause thyroid goiter?

Can celiac disease cause thyroid goiter?

Not at all: In CD your body makes antibodies that attack the gut tissue. These antibodies do attack the thyroid & do not cause goiter. The fact that you have CD makes you more prone to quirks in your immune system such as an immune attack on your thyroid gland. People should never self label as CD, but have the tests done and medical follow up because of the added risk of other autoimmune diseases or cancer. ...Read more

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Is there acinar cell loss in type 2 diabetes ?

Is there acinar cell loss in type 2 diabetes ?

See below: The reason why acinar cells become atrophic is not clear, most evidence points to an important role of Insulin as a trophic agent, although other factors including autoimmunity against exocrine tissue and vascular damage (microangiopathy) cannot be excluded. ...Read more

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K elevated suspect hemolysis of sample pres. Pat. No lab review the significant abnormalities the mild lower protein diet & mild monocytosis.Means ?

K elevated suspect hemolysis of sample pres. Pat. No lab review the significant abnormalities the mild lower protein diet & mild monocytosis.Means ?

Incomplete info: The information you provided is not readily understandable. Please note that all lab results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. ...Read more

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Is a hyperactive thyroid related to abnormal liver function?

Is a hyperactive thyroid related to abnormal liver function?

Yes: Hyperthyroidism can cause elevated liver enzymes. Drugs used to treat hyperthyroidism can also cause liver enzyme elevation. Discuss with your doctor what is causing what. Sometimes the simplest thing you can do is to treat the hyperthyroidism (curative) and see what happens to the liver enzymes. In all cases, you must follow the enzymes for trends. ...Read more

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Are these labs cause for concern? Calcium 8.7 L Creatinine 0.61 L Anion Gap 13.9 H Epithelial Cells- Many WBC-10-20

Are these labs cause for concern? Calcium 8.7 L
Creatinine 0.61 L
Anion Gap 13.9 H
Epithelial Cells- Many 
WBC-10-20

May be WBC: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, I trust the WBC 10-20 was in urine. If so, it should be repeated with proper urine collection of mid-stream specimen, after cleaning the external genitalia. Your doctor can advise on proper collection technique. Others are okay. ...Read more

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Chloride 94.9 L, Anion Gap 16.1 H, AST 58 H, Immature Granulocytes ABS 0.01 H,Ketones urine SMALL NEG. A, specific gravity urine <1.005 L. ?

Chloride 94.9 L, Anion Gap 16.1 H, AST 58 H, Immature Granulocytes ABS 0.01 H,Ketones urine SMALL NEG. A, specific gravity urine <1.005 L. ?

Plan: It's not clear what you want to know. To explain your abnormalities we need to know your primary condition. Your doctor who know your clinical symptoms and your previous results should explain it to you. ...Read more

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Can a pheochromocytoma produce a dopamine excess syndrome, or symptoms of hormonal imbalance?

Can a pheochromocytoma produce a dopamine excess syndrome, or symptoms of hormonal imbalance?

Yes Hormonal Excess: Pheochromnocytoma can be functional in which case it produces excess of adrenaline leading to high blood pressure and episodes of anxiety/nervousness. I do not think there is too much of Dopamine excess problem. You should get to see an endocrinologist. To help you out. ...Read more

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Can my heterozygotes status of congenital adrenal hyperplasia (21-Hydrolaxe deficiency, salt-wasting) explain hirsurtism & symptoms like polydipsia?

Can my heterozygotes status of congenital adrenal hyperplasia (21-Hydrolaxe deficiency, salt-wasting) explain hirsurtism & symptoms like polydipsia?

Maybe: Hydroxylase deficiency is actually a continuum, and there are many alleles. A workup is probably not worthwhile. Manage unwanted body hair with electrolysis or lasers -- you're doing yourself a favor. If your urinalysis (chemical, sediment), renal functions (BUN, creatinine) and concentrating ability (SG >1.020) while thirsty) are normal, I would not recommend further studies. ...Read more

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Can my carrier status of congenital adrenal hyperplasia (21-Hydrolaxe deficiency, salt-wasting) explain my high basal cortisol?

Can my carrier status of congenital adrenal hyperplasia (21-Hydrolaxe deficiency, salt-wasting) explain my high basal cortisol?

No: Spot "basal cortisol" levels mean nothing except in context. They help rule some things in and some things out. The highest basal cortisol levels have been found in soldiers in the battlefield and medical students in exams. Ignore all "pop" sites relating to pituitary / adrenal disease and remember that reference ranges are set so that many healthies fall outside on either end. ...Read more

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What is the definition or description of: congenital adrenal hyperplasia?

What is the definition or description of: congenital adrenal hyperplasia?

See below: It is a collection of genetic conditions that limit your adrenal glands' ability to make certain vital hormones. In most cases of congenital adrenal hyperplasia, the adrenal glands don't produce enough cortisol. The production of two other classes of hormones also may be affected, including mineralocorticoids (for example, aldosterone) and androgens (for example, testosterone). ...Read more