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Doctor insights on: Compare Prednisone And Methylprednisolone

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Dr. Marc Lorber
855 Doctors shared insights

Methylprednisolone (Definition)

Methylprednisolone (medrol) is a steroid. It's in the same family as Prednisone but is a bit more potent. Medrol (methylprednisolone) is used to treat a variety of acute and chronic inflammatory conditions such as asthma, gout, and rheumatoid arthritis. Medrol (methylprednisolone) like other steroids have many side effects especially if used long term. Common ones: weight gain, ...Read more


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What is differences between methylprednisolone, prednisone, and prednisolone? Which one better (have less sx)?

What is differences between methylprednisolone, prednisone, and prednisolone? Which one better (have less sx)?

No big difference: In practice, they are not that different although theoretically methylprednisolone may have a razor-thin edge and is available in injectable form. ...Read more

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Should I worry abt side effects from Medrol (methylprednisolone) dose pk? I have dysautonomia & BP can be a little unpredic, but I've done fine in the past w/prednisone.

Should be OK: Most dose packs start about 24mg and taper down fairly quickly, so should not be a big problem. If concerned, should always ask either your prescribing dr, primary dr (if different), or pharmacist. ...Read more

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Did a week of prednisone 2 months ago, then a week 1 month ago. Now, have a severe migraine and am considering a week of medrol (methylprednisolone). safe? Options limited

Did a week of prednisone 2 months ago, then a week 1 month ago. Now, have a severe migraine and am considering a week of medrol (methylprednisolone). safe? Options limited

?: Generally speaking it is safe, but this is rather a medical decision in the context of your clinical situation, your doctor would know better the risks/benifits of plan of treatment, good luck ...Read more

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Have dysautonomia. Notice that I feel much better when on medrol, (methylprednisolone) prednisone for OTHER conditions. Would florinef feel just as good if taken daily?

Have dysautonomia. Notice that I feel much better when on medrol, (methylprednisolone) prednisone for OTHER conditions. Would florinef feel just as good if taken daily?

Adrenal steroids: Medrol (methylprednisolone) and prednisone are glucocorticoid hormone meds and have anti inflammatory actions as well as some salt retaining actions. These mimic cortisol. They elevate glucose and increase appetite. A positive mood is another effect. Florinef mimics aldosterone. It is salt retaining principally. It has no cortisol effects. Does not elevvate mood. Preserves blood volume. Thus supports BP. ...Read more

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Hi I started off on some prednisone for a severe case of contact dermatitis but was just prescribed medrol (methylprednisolone) as a refill, is this an acceptable replacement?

Hi I started off on some prednisone for a severe case of contact dermatitis but was just prescribed medrol (methylprednisolone) as a refill, is this an acceptable replacement?

Similar: The two drugs are very similar with Medrol (methylprednisolone) presumably causing slightly less sodium retention. However, oral steroid should not be used as chronic Rx for contact dermatitis, avoidance is. If the problem persists despite avoidance of a known contact allergen, you need to see a dermatologist to look for another Dx. ...Read more

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Acute bronchitis asthma on doxcycline and prednisone, & nebulizor. Started doxi and Medrol (methylprednisolone) fri changed to prednisone can't talk w/out wheezing bad. Walking makes pant neb helps 5 min? No temp X-ray ok

Acute bronchitis asthma on doxcycline and prednisone, & nebulizor. Started doxi and Medrol (methylprednisolone) fri changed to prednisone can't talk w/out wheezing bad. Walking makes pant neb helps 5 min? No temp X-ray ok

Need to f/u with Doc: It should be getting better not worse, you might need a cxr/pulse ox and more intensive treatment to include possible admission and IV therapy. If you called my office with above complaints I would want to see you that day for re-evaluation. ...Read more

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What Is The Difference Between Prednisone And Methlprednisolone? What are the most common affects they have over time. I'm on methlprednisolone.

Similar n different: The difference between prednisone and prednisolone is that one is the precursor to the other. Prednisone is activated by enzymes in the liver to turn into prednisolone. They do have similar uses but prednisolone is more readily absorbed by the body. Prednisolone is usually used when there is liver toxicity or liver failure involved. ...Read more

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Rec'd Medrol dose pack for asthma flare-up yesterday. Doses (24mg max) seem lower than what I've taken before (40mg prednisone). Is Medrol dose pack sufficient for asthma flare? Traveling soon so want to be sure I get right treatment before leaving.

Rec'd Medrol dose pack for asthma flare-up yesterday. Doses (24mg max) seem lower than what I've taken before (40mg prednisone). Is Medrol dose pack sufficient for asthma flare? Traveling soon so want to be sure I get right treatment before leaving.

See below: Medrol is methylprednisolone, which is dosed different than prednisone. It should be sufficient to control an asthma flare. However, it depends on your other meds and how severe the flare is. I would make sure you are doing a peak flow meter daily. Also, have you noticed a decrease in the amount of rescue inhalers you are using since being on the medrol? ...Read more

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Which organ metabolizes corticosteroids? (Prednisone, Decadron, (dexamethasone) Medrol) would it be the Liver or the Kidneys?

Which organ metabolizes corticosteroids? (Prednisone, Decadron, (dexamethasone) Medrol) would it be the Liver or the Kidneys?

Liver: Liver is your answer. The kidneys get put some of the metabolites that are produced after liver starts the process off. ...Read more

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Is the risk of adrenal suppression/insuffiency increased or the same at, let's say, 35 mg prednisone compared to 45 mg? Or any dosage above 7.5 equal?

Is the risk of adrenal suppression/insuffiency increased or the same at, let's say, 35 mg prednisone compared to 45 mg? Or any dosage above 7.5 equal?

Yes: Adrenal suppression is dose related and can even occur at the replacement dose of 7.5 mg prednisone or equivalent. You have to take higher dose for stress situations ie infections bacterial or viral with increased dose of steroid. ...Read more

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Is there a natural prednisone?

Is there a natural prednisone?

Hydrocortisone: hydrocortisone is the bio identical form of prednisone. DHEA is a natural precursoer to cortisol ...Read more

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What is prednisone used to cure?

What is prednisone used to cure?

Many things: Prednisone is corticosteroid which treats many different problems such as allergic disorders, skin conditions, ulcerative colitis, arthritis, lupus, psoriasis, or breathing disorders. Prednisone prevents the release of substances in the body that cause inflammation. ...Read more

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Ok taking prednisone (deltasone)?

Ok taking prednisone (deltasone)?

It depends: As with any medication, if it is prescribed by a physician to treat a particular illness or problem it is safe, as long as it is used as prescribed. ...Read more

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What is Deltasone (prednisone) used for?

What is Deltasone (prednisone) used for?

Deltasone (prednisone): There are many, many indications for Deltasone (prednisone). See: http://www. Drugs. Com/pro/deltasone. Html ...Read more

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Please describe the medication: prednisone?

PREDNISONE A STEROID: Prednisone is a synthetic cortisone. The body makes cortisone, a natural hormone made in adrenal glands. The body converts it to Hydrocortisone to become active. 25 mg of cortisone has about same effect as 5 mgm prednisone. The average person would produce 3-6 mg of pred daily. So why use a substitute? The synthetic has more anti-inflammatory effect; but has less effect on minerals like potassium. ...Read more

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What should I expect when stopping prednisone?

What should I expect when stopping prednisone?

Prednisone: Hello, Prednisone is a steroid medication and is used by physicians quite frequently to reduce inflammation. After the medication has been completed your inflammation hopefully will be resolved. ...Read more

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Is there an effective substitute for prednisone?

Generally no: It depends on what condition the Prednisone is used for in the first place. Generally, if a corticosteroid is the only option, then any subsitute steroid would give the same risks. ...Read more

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Could I be allergic to prednisone?

Possible: Although used to treat allergies, some people indeed are allergic! ...Read more

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Is prednisone a derivative of penicillin?

No.: They are completely different. And what they do is different! Prednisone treats inflammation, such found in arthritis. Penicillin kills bacteria and is an antibiotic! ...Read more

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Is prednisone prescribed for Crohn's disease?

Yes: It is frequently used to get an active flare of the disease under control, to get the person feeling better. It is not desirable to use prednisone, though, for long term control of the disease, due to its many side effects. Other medications are used for ongoing control to reduce flares and need for prednisone. ...Read more

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What are after effects of stopping prednisone?

Varies.: Depends on how it was stopped. If stopped abruptly it may have rebound effects of the disease process that was treated. IE a flare. May feel fatigued and sluggish until the effects wears off. If you have been taking it longer than two to three weeks should be tapered off by doctors directions. If you have taken it for a long time you may symptoms of adrenal insufficiency if not tapered correctly. ...Read more

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Is prednisone normally prescribed for high collestral?

No: Prednisone is used to reduce inflammation associated with many conditions. It is not used to treat high cholesterol. ...Read more

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Is it okay for momma to breastfed while taking prednisone?

Yes: Prednisone is safe to take while breasfeeding and poses no significant risk to the infant. Very high doses may occasionally cause temporary loss of milk supply. ...Read more

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Can prednisone weakened tendons?

Typically no: There was some initial research about Anabolic steroids causing weak tendons, but this has been tough to prove again. We also use steroid injections to treat tendinopathies. As such, I highly doubt Prednisone is causing any tendon weakening. ...Read more

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What does it mean to have a suppressed immune system? E.g the immune system was suppressed by Prednisone? Does it mean that you have to avoid people?

Prednisone: Prednisone does suppress the Immune system. However it depends on how much and for how long. As a rule within 2 to 4 weeks your immune system should bounce back to normal. People on prednisone or recovering from being on prednisone usually do no have to avoid people. ...Read more

Dr. Thomas Namey
2,560 Doctors shared insights

Prednisone (Definition)

Prednisone is a synthetic cortisone. The body makes cortisone, a natural hormone made in adrenal glands. The body converts it to Hydrocortisone to become active. 25 mg of cortisone has about same effect as 5 mgm prednisone. The average person would produce 3-6 mg of pred daily. So why use a substitute? The synthetic has more anti-inflammatory effect; but has less effect ...Read more


Dr. John Feola
991 Doctors shared insights

Liquid Pred (Definition)

Liquid Pred is a corticosteroid which is a kind of ...Read more