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Doctor insights on: Coming Off Zoloft

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I am coming off Zoloft, (sertraline) it worked for me last time, saved me. this time a year or two later it isn't working. did I build up a tolerance?

I  am coming off Zoloft, (sertraline) it worked for me last time, saved me. this time a year or two later it isn't working. did I build up a tolerance?

Probably.: Some people have reported this phenomena that when they get off an antidepressant and they have to take it again for recurrence of depression, they notice that it takes a bigger dose to relieve their depression . I have read this in some literature and i have seen this with some of my patients. In fact, when the same antidepressant is restarted, you have to start with a higher dose. ...Read more

Dr. Heidi Fowler
1,073 doctors shared insights

Sertraline (Definition)

Also called zoloft, (sertraline) is one of selective serotonin reuptake inhibitors, with antidepressant/anti-anxiety actions. May cause headaches, nausea & ...Read more


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After coming off Zoloft (sertraline) for 4 months, what can I do to decrease my enormous appetite?

After coming off Zoloft (sertraline) for 4 months, what can I do to decrease my enormous appetite?

More Protein less : Carbs should lower your blood sugar and lower your sugar cravings hopefully. Try to eat complex greens like kale as well as more fish and plant based protein and less starch. ...Read more

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Does coming off Zoloft (sertraline) cause a rash?

Does coming off Zoloft (sertraline) cause a rash?

Rash: Reactions to ssri withdrawal can occur, especially if done too rapidly. I've known of itching or hive-like reactions but not rash. Did you have a rash when you started it? ...Read more

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I'm going through Zoloft (sertraline) withdrawal and I take Vicodin. Will taking Vicodin stop or slow the recovery process from coming off of Zoloft (sertraline)?

I'm going through Zoloft (sertraline) withdrawal and I take Vicodin. Will taking Vicodin stop or slow the recovery process from coming off of Zoloft (sertraline)?

No: These two medications act on the body in separate ways, so the use of Vicodin is not recommended for symptoms of withdrawal from Zoloft (sertraline). I would recommend that you discuss this with the Doctor who prescribed the Zoloft (sertraline) so that you can be appropriately weaned off the Zoloft (sertraline), if it is indicated. ...Read more

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I was prescribed Zoloft (sertraline) and don't want it. Can I pour it down toilet?

I was prescribed Zoloft (sertraline) and don't want it. Can I pour it down toilet?

Talk to your doctor: First, it is not a good idea to flush meds down the toilet due to filtration and sanitation concerns. It is best to have your physician's office, pharmacy or the police station dispose of them properly. As far as discontinuing zoloft (sertraline) on your own, i would strongly recommend that you speak with your doctor about your concerns with yhe med. ...Read more

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Will Zoloft (sertraline) help will obsessive harmful thought s that won't go away?

Will Zoloft (sertraline) help will obsessive harmful thought s that won't go away?

Maybe.: Sertraline is a reasonable drug to consider. It has more than a fair chance of working for you. ...Read more

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What should I do if I haven't felt any change after taking Zoloft (sertraline) for almost 4 weeks?

See your doctor: Like all antidepressants, it may take 4-6 weeks to feel the full benefit, but you should see at least some benefit within a couple of weeks zoloft can be dosed up to 150 mg so if you are on a lower dose, the dose can be increased. If you are already on150 mg then it is time to consider another antidepressant or adding abilify, (aripiprazole) wellbutrin, or Remeron to supplement the effects of the zoloft. ...Read more

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Does Zoloft (sertraline) make you gain weight? I've put on 30 lbs in two months and i can't loose it

Does Zoloft (sertraline) make you gain weight? I've put on 30 lbs in two months and i can't loose it

Zoloft (sertraline) weight gain: Some people are very sensitive to mental medicines and would gain weight even with meds that are not kwown to make people gain weight. If you already have a weight issue and cannot lose weight easily, zoloft (sertraline) can also cause you some weight gain even thought it causes the least of that. If you already have a healthy lifestyle, please make it better, if not then try to adopt a healthy one. ...Read more

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I feel like i've lost myself while being on Zoloft (sertraline) but i can't stop taking it what should I do?

Zoloft (sertraline): Not sure what dose u r taking & whether your symptoms started after increasing the dose, but i recommend reviewing those possibilities with your prescribing doctor to see if lowering the dose might be an option. ...Read more

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My normal 50 mg Zoloft (sertraline) doesn't help me anymore so I double dosed and I feel better. Is that okay?

My normal 50 mg Zoloft (sertraline) doesn't help me anymore so I double dosed and I feel better. Is that okay?

Yes, but....: Yes, but, first, you're lucky that you haven't experienced an adverse reaction to doubling your dose. We always advise patients only to change their medication with their physician's advice & consent, but, now that you've done so, please let your doctor know! Thanks! ...Read more

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I've been taking 1 50mg Zoloft (sertraline) a day , it hasn't been helping. Would it hurt me if I take 2 of the 50mg a day?

I've been taking 1 50mg Zoloft (sertraline) a day , it hasn't been helping. Would it hurt me if I take 2 of the 50mg a day?

Don't know: what condition you are being treated for? Don't know how long you have been on this dose? It can take 4 to 6 weeks to get a full response of zoloft (sertraline) at your current dose. Please don't make any changes to your medications without discussing with your physician/ psychiatrist. ...Read more

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I'm on 50mg of Zoloft, (sertraline) once a day. I accidentally took two doses tonight (wasn't thinking). Should I worry about anything?

I'm on 50mg of Zoloft, (sertraline) once a day. I accidentally took two doses tonight (wasn't thinking). Should I worry about anything?

Zoloft (sertraline) Effects: Zoloft (sertraline) is a medication for treatment of Depression. Zoloft (sertraline) 50mg/day is average maintenance dose “I wasn't thinking” suggests that you feel overwhelmed with stress Zoloft (sertraline) may cause Nausea, insomnia. Anxiety, agitation, irritability, dizziness, headache Treatment of Depression and anxiety is Therapy, Medication, Breathing Relaxation, Visual imagery, Yoga, and Meditation See your Psychiatrist ...Read more

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Mdd controlled w/zoloft. The last few days i'm disinterested, feel worthless, just want to lay in bed. Hasn't been this bad in a while. Advice?

Mdd controlled w/zoloft. The last few days i'm disinterested, feel worthless, just want to lay in bed. Hasn't been this bad in a while. Advice?

Depressive relapse: It's that time of year again. You could have a seasonal mood disorder component, or your zoloft (sertraline) may have hit a plateau and need an increase. Did u get a different generic? If things are real bad your psychiatrist may add in any number of agents. Get in touch with your psych soon. They will know what to do. If you have a trauma history, you may need to expand cbt to include trauma work. ...Read more

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Dr. Alan Ali
1,028 doctors shared insights

Zoloft (Definition)

Zoloft is a serotonin reuptake blocker which is a kind of ...Read more