Doctor insights on:
Combined Immune Deficiency Disease
Can you tell me if i were to mention immune deficiency, what diseases would you immediately think of?
Immunodificiency: Acquired immunodeficiency would be HIV infection where the virus kills your t lymphocytes. Primary immunodeficiencies diseases are many depending on which immune cells are affected. They are due to genetic mutations in one of the steps that immune cells develop or the process of making cytokines. You can get examples of those diseases by visiting www.Primaryimmune.Org. ...Read more
There are many: There are well over 100 hereditary / genetic deficiencies in components of the immune system. Illnesses from malnutrition to cushing's suppress immunity. Different cellular components may become depleted in a host of illness or as a result of medication. ...Read more
Medical evaluation: A clinical evaluation ireviewing the medical history and physical exam will suggest an immune deficiency, which can be confirmed by testing the presence of elements of the immune system: cells, immunoglobulins and other proteins, and immune function testing in especialized laboratories. Neonatal screening for severe immune defects affecting t cell, using the blood spots is available in a few state. ...Read more
See an immunologist: There are certain warning signs, like multiple ear/sinus/skin infections each year, multiple pneumonias in our lifetime, requiring prolonged antibiotics to clear infections, or a family history of immunodeficiency. A clinical immunologist can perform special tests to determine if your immune system is working properly. They can also determine proper treatment if a deficiency is found. ...Read more
At birth, prenatal: In families with an affected member who has a gene defect, this gene can be tested prenatally. Newborn screen for t cell deficiencies has been implemented in 10 states. Studies of the immune system can be done at any age if there is an immune deficiency is suspected. ...Read more
Everywhere: Some immune disorders lead to more upper respiratory infections, or more skin infections, for example. This is because the different defects in the immune system makes you unable to fight those particular types of infections. But, the cells, antibodies, and proteins of the immune system are basically produced in the bone marrow and travel throughout your body. So you could be affected anywhere. ...Read more
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