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Doctor insights on: Colorectal Cancer Staging Tnm

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Describe breast cancer staging according tnm?

Describe breast cancer staging according tnm?

Tumor,Nodes,Mets: The t, n, m system classifies breast cancers based upon tumor size(t), lymph node status(n), and presence of cancer elsewhere in the body(m). Stage i is limited to small cancers +/- microscopic ln disease. Stage ii describes tumors 2-5cm +/- ln disease. Stage iii is for more advanced tumors (>5cm, skin/chest wall involvement) +/- multiple/distant ln. Stage IV describes metastatic disease. ...Read more

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Dr. Herbert Hoover
236 doctors shared insights

Colorectal Cancer (Definition)

Colorectal cancer is cancer of the colon or rectum. The cells lining the colon or rectum become abnormal and grow uncontrollably. They start as polyps. Symptoms include blood in the stool, constipation, loss of appetite, and weight loss. This cancer can be prevented through early screening, if a polyp is detected during a colonoscopy and excised. Additionally, a high fiber diet with plenty of water and a ...Read more


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Is metastatic colon cancer curable?

Is metastatic colon cancer curable?

Possible: But less than 20% survive 5 years. Depends on where the metastases are and how numerous and size. Solitary liver mets without evidence elsewhere in the body can be cured with a liver resection. Diffuse mets to numerous body parts rarelyare curable. ...Read more

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Colon cancer chemo necessary?

Colon cancer chemo necessary?

Depends on stage: Chemotherapy is never used for stage 1 cancers (early). It is sometimes used in stage 2 cancers (early but more advanced than stage 1). Chemotherapy is definitely beneficial in stage 3 cancers (locally advanced) and in stage 4 cancers (distant spread). ...Read more

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Dr. Liawaty Ho Dr. Ho
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Breast cancer staging according TNM means what?

Dr. Liawaty Ho Dr. Ho
3 doctors agreed:
Breast cancer staging according TNM means what?

TNM breast cancer: Tnm is one of the staging system commonly used for cancer. It stands for t-tumor ( the size of the tumor- the bigger is the tumor the higher is the stage) ; n- nodal status ( involvement to the lymph glands) - and m- presence of metastatic disease to the distant organ. See more here: http://cancer.Gov/cancertopics/wyntk/breast/page7. ...Read more

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Is stage 4 colorectal cancer curable?

Is stage 4 colorectal cancer curable?

Majority will be No: When the cancer has spread to other organ beyond the primary organ-metastatic disease- or stage 4- , majority , it is an incurable disease. In a very selected case, when the metastatic disease is very limited - 1 or 2- only in the liver or only in the lung- and no other disease anywhere else and if surgery can be done to remove completely, attemp to cure the cancer can be done with chemo & surgery. ...Read more

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Prognosis stage 3 breast cancer?

Prognosis stage 3 breast cancer?

Curable!: Stage 3 means the tumor is large and/or the cancer has spread to many lymph nodes. It can still be cured with a combination of surgery, chemotherapy and radiation therapy. The risk of cancer returning depends on many factors-- age, # of involved lymph nodes, and whether the cancer has hormone receptors or her2. About 50% of stage 3 breast cancer patients are cured. Have hope! ...Read more

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Is metastatic anal cancer terminal?

Is metastatic anal cancer terminal?

Unfortunately: Metastatic disease (also known as stage 4) is usually not curable by todays treatments. Although use of chemotherapy may improve survival and may rarely put someone into a temporary remission the disease usually returns or more often does not go away and eventually progresses and the patient will eventually succumb to it. ...Read more

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What is metastatic rectal cancer?

What is metastatic rectal cancer?

Tumor has spread: 'Metastatic' refers to a cancer that has spread to another site away from where it started. This happens when cancer invades blood vessels and lymphatics, allowing the cancer cells to spread and deposit in other organs. So ' metastatic rectal cancer ' means a tumor that started in the rectum is now outside the rectum, in other organs (liver is most common). ...Read more

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Colon surgery:tumor size=2cm.Pathologic staging(pt3, n1b, mx).2/17 lymph nodes show metastatic.Margins of resection free of carcinoma.Need chemotherapy?

Colon surgery:tumor size=2cm.Pathologic staging(pt3, n1b, mx).2/17 lymph nodes show metastatic.Margins of resection free of carcinoma.Need chemotherapy?

Yes: Chemotherapy regimens based on the drug Fluorouracil (5-fu) have been part of the treatment for high-risk stage ii or stage iii colon cancer. Many clinical trials have shown that these regimens improve overall survival primarily by reducing the high risk of recurrence within the first two years after surgery. ...Read more

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Prostate cancer treatment?

Prostate cancer treatment?

First question: Is whether treatment is necessary, depends on gleason score and psa. Treatment may not add value to you. Watchful waiting follows your psa #, rate of rise. If your gl >/= 7, psa > 10ng/ml, best option is radiotherapy, +/- anti-hormone. Get a few opinions. Do not act in haste. ...Read more

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What is metastatic prostate cancer?

What is metastatic prostate cancer?

Metastasis: in general, metastasis refers to a cancer that has gone from the organ of origin to other parts of the body ...Read more

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Is colon cancer curable?

Yes: Yes. Many people are cured with colon cancer. If found early surgery alone may be curable. If more advanced (eg, lymph node involvement or metastatic = spread to areas outside of colon), then chemotherapy may be needed. While less likely, even a few % of people with metastatic colon ca may be cured. ...Read more

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What is metastatic pancreatic cancer?

What is metastatic pancreatic cancer?

Moved to other organ: Metastatic pancreatic cancer is cancer that started in the pancreas and then moved to other organs. Most commonly it moves to the liver. It can spread throughout the body though. ...Read more

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Is advanced stage colon cancer treatable?

Is advanced stage colon cancer treatable?

Yes and no: It is treatable but not curable. That is, you can treat it and may knock it down for a while ..t but it will always come back. But there are many factors that play into it. See cancer.org or cancer.gov for excellent information on the stage and what to expect. ...Read more

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Is stage 3c breast cancer curable?

Is stage 3c breast cancer curable?

Yes: ...In theory, with aggressive multi modality therapy (surgery plus chemo plus radiation +/- hormones +/- herceptin). The risk of relapse is high but you do all you can and hope for the best. If this is about you, fight well and best wishes. ...Read more

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Chances of metastasis to lung of stage II colon cancer?

Chances of metastasis to lung of stage II colon cancer?

Low but not zero: Stage ii colon cancer means no lymph node involvement by definition, but inadequate lymph node sampling (surgical resection) may "understage" the cancer, so make sure enough ln were taken -minimum of 12! even with appropriate surgery, mets may still occur, although very unusual, so discuss with your treating docs. A pet/ct may give some reassurance so ask if this can be done. ...Read more

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Stage 2B IDC breast cancer, her2+/ER/PR+Neoadjuvant taxol, (paclitaxel)A/C,lumpectomy,rads, lymphovascular invasion. What does this mean for prognosis & follow up?

Stage 2B IDC breast cancer, her2+/ER/PR+Neoadjuvant taxol, (paclitaxel)A/C,lumpectomy,rads, lymphovascular invasion. What does this mean for prognosis & follow up?

Prognosis fair: Stage IIb breast cancer is usually palpable at 2-5 cm. and at time of procedure to remove lesion, sentinel nodes are + suggesting axillary dissection and reason for neoadjuvant therapy. Lymphovascular invasion increases chance for recurrence. With Her2+ Herceptin (trastuzumab) with chemo should be used and PET/CAT needed to assure met foci not missed in distal organs. Carful follow up needed. ...Read more

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Is stage IV pancreatic cancer terminal?

Is stage IV pancreatic cancer terminal?

Yes?: As a rule, stage 4 cancer of the pancreas is incurable. As to being terminal, it depends on the definition. If you mean it will kill the patient at some point, the vast majority of the times the answer is yes. If you mean it will kill the patient right away, it depends on the situation. Never say never, though, some patients have surprised me in the past. Sorry if it is about you or a loved one. ...Read more

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What ages does colorectal cancer affect?

It varies: Colon cancer can strike from the 20s and beyond, but is much more common in people in their 50s to 70s hence the recommendations to not routinely do colonoscopies in people before the age of 50. Colon cancer that presents before 60 is often genetic whereas after 60 is more likely due to environmental factors like smoking and red meat. ...Read more

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Can you tell me what is colorectal cancer?

Can you tell me what is colorectal cancer?

CRC: It is cancer of the large intestine (which includes the colon and the rectum, the part labeled #5 in the illustration). It is the third most common cancer for both sexes and one of the few for which there is successful screening methods. Usually starts in a polyp and can be associated with several inherited traits. ...Read more

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Colorectal cancer is really serious, right?

Colorectal cancer is really serious, right?

Serious, right!: Colorectal cancer is very serious. It can also be completely and relatively easily cured if detected early. Screening should be performed at around 50 years of age. Certain people are at higher risk and should be checked earlier. Colonoscopy is the most reliable test at this time. If you are having symptoms that concern you, you should ask your dr. ...Read more

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How is colorectal cancer diagnosed usually?

How is colorectal cancer diagnosed usually?

Colonoscopy, imaging: And biopsy. A lesion may be detected on colonscopy or barium enema or the more recent ct scans. The lesion is biopsied and the tissue examined by a pathologist to make the diagnosis. Colon cancer may be suspected if there is blood in stool, either obvious or occult. ...Read more

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What are early symptoms of colorectal cancer?

What are early symptoms of colorectal cancer?

May be none: Many early cancers do not have any symptoms and that is why it is important to have screening tests done, e.g., colonoscopy at age 50 for prevention of colo-rectal cancer. Symptoms may be change in bowel habits, bleeding per rectum, anemia, bowel obstruction and the first symptoms may be from metastases to other organs such as liver. ...Read more

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What are the chances of colorectal cancer at age 37?

What are the chances of colorectal cancer at age 37?

Low: Chances are low, but this is not impossible. If you have a strong family history then the chances go up. Most people don't need any screening for colorectal cancer until age 50, or 10 years younger than age of diagnosis for your relative. ...Read more

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What are some pre-cancerous signs of colorectal cancer?

Colonic polyps: Nearly all colon cancers arise in colon polyps. Unfortunately, colonic polyps are generally asymptomatic and require colonscopy of barium enema for detection. Newer imaging studies may make the detection easier. Patients with inflammatory bowel disease have higher incidence of colon cancer. A family history of colon cancer is an other "sign". ...Read more

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I know colorectal cancer has consequences. What are they?

Colorectal cancer: Consequences include need for surgery and other forms of treatment such as chemotherapy radiation. People may live for along time if disease caught early. ...Read more

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What is the definition or description of: colorectal cancer?

What is the definition or description of: colorectal cancer?

Invasion: Colorectal cancer is a term to signify invasion accross a layer of the lining of the colon or rectum. A polyp can show abnormal features up to a point and still not be considered an invasive cancer. Once we use the term colon or rectal cancer, the cells are not only atypical, they have shown invasion. ...Read more

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Need expert help here. What are some signs of colorectal cancer?

Need expert help here. What are some signs of colorectal cancer?

Nonspecific signs: There may be blood in the stool, either visible or only detectable by testing; stool may be black (which means blood); change in bowel habits such as diarrhea or constipation or change in diameter/consistency of stools; fatigue, weakness, shortness of breath. There can be crampy abdominal pain and a feeling that your bowels are not emptying completely. There may be unexplained weight loss. ...Read more

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Is colorectal cancer always fatal?

Is colorectal cancer always fatal?

No: Most early colon cancers have a very high success rate of long term survival rate. More advanced cancers that spread to other sites do not have the same success rates, but can still live for years. ...Read more

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What is the pathology of colorectal cancer ?

Adenocarcinoma: Colorectal cancer is usually adenocarcinoma that developed from a underlying polyp. For details on staging visit http://www.Cap.Org/apps/cap.Portal?_nfpb=true&cntvwrptlt_actionoverride=%2fportlets%2fcontentviewer%2fshow&_windowlabel=cntvwrptlt&cntvwrptlt%7bactionform.Contentreference%7d=committees%2fcancer%2fcancer_protocols%2fprotocols_index.Html&_state=maximized&_pagelabel=cntvwr. ...Read more

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Who should get screened for colorectal cancer?

Who should get screened for colorectal cancer?

Everyone, most >50: Most people are considered "average risk" for colorectal cancer, and should begin screening @ 50, typically with a colonoscopy. Some people at increased risk, such as those with inflammatory bowel disease or a family history of colorectal cancer. These people may need screening at a younger age-generally 10 yrs earlier than the age when their relative got colon cancer. Talk w/ your doctor. ...Read more

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What are the signs and symptoms of colorectal cancer?

What are the signs and symptoms of colorectal cancer?

None: Usually there are no symptoms. Later can develop intestinal or rectal bleeding, anemia, weight loss, intestinal blockage, change in bowel movements, etc. ...Read more

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What can be done about a stoma and colorectal cancer?

What can be done about a stoma and colorectal cancer?

May be temporary: Most stomas that are created following colorectal surgery are temporary. The permanent colostomies are performed when the tumor involves rectal sphincter and an APR is performed. Otherwise the diversion performed is to protect an anastomosis and can be closed several months later when the suture line has healed. A colostomy is also performed when there is bowel obstruction and diversion needed. ...Read more

Amanda Xi Dr. Xi
5 doctors agreed:
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Is it possible to have colorectal cancer without having polyps?

Amanda Xi Dr. Xi
5 doctors agreed:
Is it possible to have colorectal cancer without having polyps?

Possible: For a small percentage of colon cancers caused by lynch syndrome (also known as hnpcc - hereditary nonpolyposis colon cancer), there is an absence of polyps. ...Read more

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Dr. Barry Rosen
4,363 doctors shared insights

Cancer (Definition)

Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more


Staging (Definition)

Many diseases have specific treatments based on their severity. A disease can have certain criteria to determine their severity and applying this criteria to determine how advanced the disease state is called staging. Most commonly this is applied to cancer, and be determining how far the cancer has spread locally and/or to distant sites a stage of cancer can be ...Read more