Top
20
Doctor insights on: Colorectal Cancer Pharmacogenomic

Share
1

1
What sort of disease is colorectal cancer?

What sort of disease is colorectal cancer?

Large bowel cancer: Colon and rectum form the large intestine (large bowel). Cancer of the large intestine is generally called colorectal cancer. Specifically, cancer of the colon is colon cancer. Cancer of the rectum is rectal cancer. People over 50 should have screening colonoscopy or occult blood test. Treatment for stages 1, 2, and 3 are mainly surgery. Chemo is for stages 3 and 4, and some stage 2. ...Read more

See 1 more doctor answer
Dr. Herbert Hoover
236 doctors shared insights

Colorectal Cancer (Definition)

Colorectal cancer is cancer of the colon or rectum. The cells lining the colon or rectum become abnormal and grow uncontrollably. They start as polyps. Symptoms include blood in the stool, constipation, loss of appetite, and weight loss. This cancer can be prevented through early screening, if a polyp is detected during a colonoscopy and excised. Additionally, a high fiber diet with plenty of water and a ...Read more


2

2
What are the symptoms of colorectal cancer?

What are the symptoms of colorectal cancer?

Varied: Lesions of the right colon hard to dx early since bowel content is liquified. On left side, content is solid and if lesion present, obstruction occurs if lesion circumferential or bleeding noted from irritation of hard stool against lesion. On rt. as well as left side ideal time to define is before symptoms by routine colonoscopy ...Read more

See 1 more doctor answer
3

3
What are my chances of recovery from colorectal cancer?

What are my chances of recovery from colorectal cancer?

Usually great.: Usually patients are able to make a great recovery after surgery for colorectal cancer, but it depends on multiple factors. The main determinants are the stage of the cancer, and how healthy the patient is before the operation. For patients whose tumors have not spread to lymph nodes there is about a > 85% chance of surviving 5 years. Spread to other organs significantly decreases survival. ...Read more

See 1 more doctor answer
4

4
How are the survival rates for colorectal cancer known?

How are the survival rates for colorectal cancer known?

Statistics: Most states collect cancer data that provide the basis for incidence, mortality and survival rates. ...Read more

6

6
Is colorectal cancer always fatal?

No: Most early colon cancers have a very high success rate of long term survival rate. More advanced cancers that spread to other sites do not have the same success rates, but can still live for years. ...Read more

See 2 more doctor answers
7

7
What is the pathology of colorectal cancer ?

What is the pathology of colorectal cancer ?

Adenocarcinoma: Colorectal cancer is usually adenocarcinoma that developed from a underlying polyp. For details on staging visit http://www.Cap.Org/apps/cap.Portal?_nfpb=true&cntvwrptlt_actionoverride=%2fportlets%2fcontentviewer%2fshow&_windowlabel=cntvwrptlt&cntvwrptlt%7bactionform.Contentreference%7d=committees%2fcancer%2fcancer_protocols%2fprotocols_index.Html&_state=maximized&_pagelabel=cntvwr. ...Read more

See 1 more doctor answer
9

9
What methods are used to screen a person for colorectal cancer?

What methods are used to screen a person for colorectal cancer?

History: Get personal and family history of colon cancer. Ask if history of colitis, familial polyposis, ibs, lunch syndrome, rectal bleeding, obesity, age over 44yo, rectal mass., un explained anemia needs to be evaluated. Colonoscopy is by far the best way to screen for colon cancer. ...Read more

See 1 more doctor answer
10

10
How likely is it that I have colorectal cancer if my dad had it?

How likely is it that I have colorectal cancer if my dad had it?

More likely.: Most colon cancer is from adenomatous polyps. Hereditary nonpolyposis colon cancer comes from hmsh2 and hmlh1 genes on chromosomes 2 and 3 respectively which repair dna. These have mutations that can lead to colon and other cancers. Diagnosis needs three or more relatives with colon cancer, with one being a first degree relative, >1 case before 50, and >=2 generations. ...Read more

See 3 more doctor answers
11

11
Where do I go to get colorectal cancer gene test?

Where do I go to get colorectal cancer gene test?

Discuss with your MD: Some evaluation /analysis can be done on the cancer tissue . Your oncologist can ask the pathologist to test it. Then, your oncologist can refer you to a genetician /genetic counsellour to start with -whom then will order the necessary genetic test based on your personal/family history. Discuss in detail with your oncologist. ...Read more

12

12
How much does a colorectal cancer gene test cost?

How much does a colorectal cancer gene test cost?

Expensive: The genetic test commercially available for hereditary colon cancer predisposition costs between $3000-4000. Most insurance companies will pay for the test as long as certain criteria are met. ...Read more

13

13
What are the treatments for metastatic colorectal cancer?

What are the treatments for metastatic colorectal cancer?

Chemo & RARE sx/rads: Chemo represents answers one through nine, however, if one has a solitary metastasis in the liver that is able to be surgically removed safely, this could be answer 10. Also, focused radiation (cyberknife or radiosugery as it it called) can sometimes be used to treat isolated mets if surgery is not possible. ...Read more

See 3 more doctor answers
14

14
What are procedures used for colorectal cancer screening?

Several possible: You can check your stool for hidden blood, get colonoscopies (checks whole colon), or get a combination of flexible sigmoidoscopies (checks part of colon) and stool checks. Screening should be done between age 50 and 74 unless there is another reason to start earlier or go later. All of these methods work! a good proven prevention guide by age is an iphone app called my health checklist 2012. ...Read more

See 1 more doctor answer
15

15
Colon cancer or colorectal cancer, what's the difference?

Colon cancer or colorectal cancer, what's the difference?

Location: Cancers that arise from the epithelium of the large intestine are similar in most ways whether they are in the colon or rectum. Discussions of "colon cancer" unspecified usually mean "colorectal" unless stated otherwise. Usage, including by me, is often sloppy. ...Read more

16

16
When does someone need to see a colorectal cancer surgeon?

When does someone need to see a colorectal cancer surgeon?

Colon tumor: Most patients with colorectal symtoms are seen by a GI clinician. If a lesion found which can not be removed by colonoscopy then patient is referred to colon surgeon who will review situation to define which interventional procedure is needed to completely remove the tumor. This may be done laparoscopically or if needed by formal laparotomy ...Read more

17

17
What foods can one eat before a colorectal cancer screening?

Generally none: Generally it is recommended you not eat solid food the day prior to your colonoscopy. It may be helpful to avoid salads and corn for 2-3 days. ...Read more

See 1 more doctor answer
18

18
Is colorectal cancer caused by a genetic defect leading to polyps?

Is colorectal cancer caused by a genetic defect leading to polyps?

Yes and no: All benign and malignant tumors result from accumulated genetic mutations. There are a few hereditary illnesses in which a child inherits a first mutation in the series that leads to colon cancer. However, most people with colon cancer began life with a genome free of cancer-causing mutations. Benign polyps may or may not acquire additional mutations and turn cancerous. ...Read more

19

19
What is the difference between having colorectal cancer and hemorrhoids?

What is the difference between having colorectal cancer and hemorrhoids?

Lots!!!: Hemorrhoids don't turn into cancer but often anal lesions are misdiagnosed as hemorrhoids and may be an anal or rectal cancer. In either case it should be correctly diagnosed and receive the proper treatment and recommendations. ...Read more

See 1 more doctor answer
20

20
Are colorectal cancer and colon cancer the same thing with different locations?

Yes and no: Both are adenocarcinomas of the 'large intestine' broadly speaking. However, due to several anatomic differences, colon and rectal cancer behave differently. For that reason the preoperative staging is different and the treatment can be different (surgery +/-chemotherapy for colon cancer, surgery +/- chemoradiation therapy for rectal cancer). The functional outcomes are different as well. ...Read more

See 1 more doctor answer
Dr. Barry Rosen
4,348 doctors shared insights

Cancer (Definition)

Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more


Dr. Keith Monson
209 doctors shared insights

Proctology (Definition)

Proctologists are physicians who have specialized knowledge to diagnose and surgically treat disorders affecting the colon, rectum, and anus. Such disorders may include hemorrhoids, colorectal ...Read more