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Doctor insights on: Colon Cancer Tubulovillous Adenoma With High Grade Dysplasia

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39y/o, had 2 polpys removed (sigmond & descending, villous adenoma w/high grade dysplasia). Will I get colon cancer even though 2 polyps were removed?

39y/o, had 2 polpys removed (sigmond & descending, villous adenoma w/high grade dysplasia). Will I get colon cancer even though 2 polyps were removed?

Not sure if: Family history or leeding led to your colonoscopy, but it showed its value. You are not predestined to get invasive cancer, but the findings warrant follow up to snip dangerous polyps before they invade, and gain access to nodes and blood steam. Your colonoscopist can tell you schedule for surveillance. ...Read more

Dr. Barry Rosen
4,351 Doctors shared insights

Cancer (Definition)

Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more


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I had two tubular adnomas removed in '09 at 33, one hyperplastic and one tubular adenoma removed in '12. Am I likely to get colon cancer. No fam hstry?

Tubular adenomas: The fact that you have tubular adenomas at such an early age probably does slightly raise your lifetime risk of colon carcinoma. However, now that you know you can have careful followup and screening to make sure all adenomas are removed before they can develop into colon cancer. ...Read more

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Can a person develope obstructive colon cancer two years after scope that showed 1 hyper and 1 adenoma polyp and diverticulosis?

Yes: It is possible, although rare.
The most common explanation would have been a missed colon polyp during the past procedure, due to either poor colon prep (stool in colon) or incomplete procedure due to technical reasons.
Aggressive cancers (with genetic mutations - usually hereditary) can lead to obstructive cancer in a year. ...Read more

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Colon biopsy:huge tubulovillous adenoma with marked atypia, multi foci adenocarcinoma in situ &one tiny focus suggestive of micro invasion. Is it cancer?

Colon biopsy:huge tubulovillous adenoma with marked atypia, multi foci adenocarcinoma in situ &one tiny focus suggestive of micro invasion. Is it cancer?

Yes: Adenocarcinoma in situ is cancer. The area suggestive of micro invasion suggests you should have rather aggressive followup screening which I am sure your doctor has, or will soon suggest. Stay on top of this and follow his/her advice. ...Read more

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Is it still possible for me to have familial adenomatous polyposis if parent had colon cancer?

Is it still possible for me to have familial adenomatous polyposis if parent had colon cancer?

Yes if parent has it: Yes if parent had colon cancer due to familial adenomatous polyposis, you could have inherited, only way to rule out is to see your physician, and have a colonascopy done. ...Read more

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What arethe chances of lynch syndrome if no colon ca runs in the family? I had a sessile adenoma at 27 but no fam history of cancer other than 1 had lungca

What arethe chances of lynch syndrome if no colon ca runs in the family? I had a sessile adenoma at 27 but no fam history of cancer other than 1 had lungca

No chance: Your family history reveals no evidence for lynch syndrome, hereditary non-polyposis colon cancer or other hereditary cancer syndromes based on the information given. Would run out of space here before able to answer fully. If you want further information please refer to the amsterdam criteria and bethesda guidelines. ...Read more

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If I have polyps in the colon, aged 26- would there be an extremely high incidence of colon cancer later in life?

If I have polyps in the colon, aged 26- would there be an extremely high incidence of colon cancer later in life?

Perhaps??: There are many types of polyps, some common at younger ages, and not all polyps lead to cancer! Just having a benign hyperplastic polyp at age 26 probably doesn't influence your colon cancer risk at all! But other polyps are much more worrisome, so find out what kind you had, and discuss your personal risk with your doctor, knowing that surveillance should greatly reduce your chance of cancer. ...Read more

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If I have colon polyps at age 26, is my risk of developing colon cancer later in life very high?

If I have colon polyps at age 26, is my risk of developing colon cancer later in life very high?

Depends on polyp: Some polyps are not precancerous and thus have no bearing on future development of colon ca. Others are, however, and your doctor should discuss your risk with you depending on what was found. You can relax somewhat, knowing that regular screening has been shown to dramatically lessen your risks of future colon cancer! ...Read more

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What can a high ALT reading of 135 mean in a person with metastic colon cancer who is on oxyplatin chemo?

What can a high ALT reading of 135 mean in a person with metastic colon cancer who is on oxyplatin chemo?

Possibilities: Correlate with CT scan or PT scan: may be liver inflammation, liver metastasis, gallbladder disease or reaction to chemo. Please consult with your oncologist ASAP. ...Read more

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Why is the reccurence of colon cancer in T4 high?

Why is the reccurence of colon cancer in T4 high?

Larger tumor: A T4 tumor is simply a tumor that has invaded more deeply through the colon wall than other tumors (t1 - t3). T4 tumors invade all the way through the colon wall and may even invade other structures. Because the tumor has gotten through the colon wall, it is more likely to have deposited cells in other tissues making recurrence more likely. ...Read more

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Is a high white cell count indicative of colon cancer?

Is a high white cell count indicative of colon cancer?

No: An elevated blood white cell count can be an indication of active inflammation somewhere in your body, like infection. There are many other reasons for elevated wbc, but it is not indicative of colon cancer. ...Read more

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If I have high msi stage 2a colon cancer do I benefit from chemo?

If I have high msi stage 2a colon cancer do I benefit from chemo?

Not likely: Chemotherapy is typically not used for stage ii colon cancers. Additionally, patients with msi mutations seem to be poor responders to the chemotherapy drug typically used. ...Read more

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T3nomo colon cancer stage 2a had perforation is that high risk?

Partially yes: The staging information is generally favorable. The T3 (liothyronine) means that this tumor was involving the bowel wall but not the surrounding organs and this may have contributed to the perforation during the dissection. My advise is when you see an oncologist, make sure to point out this information. Even though you are node negative, the oncologist may be more willing to recommend chemotherapy to be safer. ...Read more

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Why isn't stomach or colon cancer chances high in. My 20s? Explain. In detail please

Why isn't stomach or colon cancer chances high in. My 20s? Explain. In detail please

It is a good thing: It's good that the risk to develop colon, stomach or other type of cancer in our 20's, in general, is not high. Unless if you have a strong family history of colon ca such as in familial adenomatous polyposis or stomach cancer, then the risk would be much higher. That is because when we are younger, the gene repair mechanism is still functioning well and exposure to carcinogenic is still limited. ...Read more

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Does the medication tricor (fenofibrate) for high triglycerides increase risk of colon cancer?

Does the medication tricor (fenofibrate) for high triglycerides increase risk of colon cancer?

No: There were concerns decades ago about Clofibrate but they came to nothing. I searched the nih database for the past 20 years and found nothing, and it makes no sense biologically. If it did, the research piranhas would have grabbed it up -- it's all about trying to discover and prove something. The fibrates have saved many, many lives and I would not be concerned. ...Read more

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Why does having had endometrial cancer increase risk of colon cancer? I have lynch syndrome but risk would be high anyway?

Why does having had endometrial cancer increase risk of colon cancer? I have lynch syndrome but risk would be high anyway?

You have not had: Enough or appropriate genetic counseling with regard to Lynch syndrome 1 or 2, to which you are cecertainly entitled. Find out which laboratory tested you for confirmation, by demanding a copy of your laboratory report, to which you are entitled, which will provide you with the number for the Genetics Counselor at that laboratory. He/she will explain the significance to you and for your relatives. ...Read more

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Can metastic colon cancer cause severe breathlessness?

Can metastic colon cancer cause severe breathlessness?

Sometimes if:: Colon cancer often spreads to the lungs and this would cause breathlessness. If for some reason the patient is very anemic it's possible he/or she would be short of breath. ...Read more

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My husband doing chemo after diagnosed with iiib colon cancer, tumor removed on #7 treatment, sugar level is really high now, what causes this?

He may be diabetic: Sone of the pre-medications we use in chemo can increase bloo dsugar. If levels are high he needs to be evalauted for diabetes and if needed treated as such. ...Read more

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Can high increasing bilirubin in metastic colon cancer with liver mets cause death? What is prognosis? Other LFT "s are normal

Can high increasing bilirubin in metastic colon cancer with liver mets cause death? What is prognosis? Other LFT "s are normal

Bilirubin: The high bilirubin will not cause death in this situation, it likely is a sign that the bile ducts are blocked up by metastatic cancer in the liver. ...Read more

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My blood work shows high mpv and low ferritin what could This be? Can low ferritin be colon cancer? And high MPV I read can mean risk of stroke

Iron deficiency: Not to worry. At your age, unless it runs in the family, there is extremely low chance this is colon cancer. Likely what your tests say is that you just have a little iron deficiency. This is very common to see in young healthy females as a result of menstrual periods and not enough dietary iron intake. The elevated MPV is likely due to secondary effects of the iron deficiency. Keep your follow up ...Read more

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I have a long family history of colon cancer, every bm is diarrhea, I'm losing weight and in severe pain, but I'm under 30. Could I have colon cancer?

I have a long family history of colon cancer, every bm is diarrhea, I'm losing weight and in severe pain, but I'm under 30. Could I have colon cancer?

Yes: Best to get these symptoms fully evaluated. You may need a colonoscopy for a definitive diagnosis. Although it is unusual for someone your age to have colon cancer, it is not impossible. Losing weight with severe pain means you need to know and not guess. Symptoms like these deserve a full evaluation in person by your health care provider. ...Read more

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I have colon cancer. On my second round of chemo. I have a severe crick in my neck ibro is not working can I take ambien (zolpidem) for sleep and oxy for pain?

I have colon cancer. On my second round of chemo. I have a severe crick in my neck ibro is not working can I take ambien (zolpidem) for sleep and oxy for pain?

Medications: It depends on what your usual regimen of medications are and what strength of oxycodone you are using. So if you regularly take ambien (zolpidem) and oxycodone there should be no problem. I would take the lowest dose of each medication and check with your personal doctor or covering doctor on call to make sure. ...Read more

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How high of a risk do I have of getting uterine, ovarian, breast, and colon cancer if I have a strong history these and more on both sides of my fam?

How high of a risk do I have of getting uterine, ovarian, breast, and colon cancer if I have a strong history these and more on both sides of my fam?

Be seen: There are many variables that you could possess. Your physician can discuss your individual risk for these varied cancers. ...Read more

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My sister is on chemotherapy (folfox for metastatic colon cancer). Recent blood test shows high WBC (14, 000) and platelets (429). Is this okay?

My sister is on chemotherapy (folfox for metastatic colon cancer). Recent blood test shows high WBC (14, 000) and platelets (429). Is this okay?

No worries.: High WBC can be due to many causes: infection, stress, steroid use, dehydration, or the use of growth factor (such as neupogen). If there is no evidence of infection, then there is nothing to worry about. High platelet count is not uncommon since it is a body's reaction to stress of any cause (platelet is an acute phase reactant). Again, nothing to worry about. All the best, hk. ...Read more

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A friend has been told they have colon cancer, diagnosed via a tumour marker blood test, high cea, CT scan showed contained mass. Is this conclusive?

A friend has been told they have colon cancer, diagnosed via a tumour marker blood test, high cea, CT scan showed contained mass. Is this conclusive?

No, but...: But very suspicious for colon cancer. If your friend is similar in age to yourself a mass in the colon on ct scan is cancer until proven otherwise. And CEA levels can go up for other reasons but, given the mass, they would strongly favor cancer. But to answer your question "no"... They are not definitive. You would need a piece of the mass under a microscope to prove definitively its cancer. ...Read more

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Is there solid science behind low fat/high fiber diet to lower risk of colon cancer for ulcerative colitis patients? Anything else preventative?

Is there solid science behind low fat/high fiber diet to lower risk of colon cancer for ulcerative colitis patients? Anything else preventative?

I am not aware: Of such data. It is generally accepted that risk of malignancy is proportional to duration of active colitis, so it follows that it is most important to keep the disease under control as much as possible. Confer with your gi specialist for specific advice in your case. ...Read more

Dr. Brad Goldenberg
13 Doctors shared insights

Colon (Definition)

The colon is another term for the large intestine. This is the final portion of the digestive system, responsible for absorbing water and storing stool before evacuation. It is divided into sections described as cecum; ascending, transverse, descending and ...Read more


Dr. Qamar Khan
12 Doctors shared insights

Colonic (Definition)

This is a combining term referring to some condition, treatment or disease of the colon. Such as colonic enema, colonic ...Read more