Doctor insights on:
Colon Cancer Therapy Safely Sex
Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more
Some response: meds like Xeloda have some tempoary benefit suppressing DNA function as an oral 5FU (fluorouracil). Long term responses are not seen requiring combination therapy to give an optimjum response. Eventually if cancer does show a good response, malignant stem cells will repopulate the site of the original metastasis. ...Read more
Depends on chemo: The side effects of chemotherapy depend on the chemos involved. In general bone marrow suppression (bms) causing lower red blood cells (rbcs) with anemia, lowered wbcs with increased risk of infection, and lowerd platelets with increased risk of bleeding. Oxalipaltin ("o" in folfox) can cause numbness or cold induced nerve pain. Irinotecan ("i" in folfiri) causes diarrhea. Etc... ...Read moreSee 1 more doctor answer
Yes: No matter what treatment, cancer of the breast does not have 100 % results. So with lumpectomy and radiation cancer can still recurr. This is why patients need to follow with all their doctors for exams and x-rays. If there is a recurrence other options exist such as mastectomy. ...Read moreSee 2 more doctor answers
Yes, absolutely: 5fu (fluorouracil) based chemotherapy is the standard chemotherapy in colon cancer. Combination of 5-FU and oxaliplatin is widely used and a standard regiment of chemotherapy in colorectal cancer. A big randoomized clinical trial in colon cancer ( mosaic study) has demonstrated the overall survival benefit of using combination of 5fu (fluorouracil)/oxaliplatin in stage iii colon cancer and limited case of stage ii disease. ...Read moreSee 1 more doctor answer
Not often: Radiotherapy can be useful in certain select cases where the Cancer is localized to one or two spots only. This means 1 patient in 5 may be suitable candidate. But you need to seek consultation with a radiation oncologist before you can get a clear cut answer for your circumstances. ...Read moreSee 1 more doctor answer
My prostate cancer is being treated with radioactive seeds (brachytherapy). What precautions should I take during and after prostate cancer brachytherapy?
You may need to take some precautions, but it depends on the type of prostate cancer brachytherapy you receive: Prostate cancer brachytherapy is designed to treat prostate cancer by delivering radiation treatment to only the prostate. This is done by implanting radioactive "seeds" containing your treatment inside your prostate gland. Prostate cancer brachytherapy can be done with different types of radioactive seeds. The amount of radiation released by the seeds and the duration of treatment depend on the type of seeds used. The lifetime radiation exposure to family members of men receiving prostate cancer brachytherapy is very low and doesn't exceed the annual limit set by the Nuclear Regulatory Commission. Although the seeds remain in the prostate for the rest of your life, the amount of radiation released by them decreases with time and eventually becomes negligible. Your radiation oncologist can provide detailed information about the specific treatment used. Recommendations for the first two months after seed implantation may include: Avoiding sexual intercourse for the first two weeks, After the first two weeks, using a condom during sexual intercourse in case a seed is passed during ejaculation, Limiting close contact with children and pregnant women, Not allowing children to sit on your lap for extended periods of time. If you travel to foreign countries, you may encounter radiation detectors at some border security checkpoints. Consider carrying a card from your radiation oncologist indicating that you have had a prostate seed implant. ...Read more
Ciii ovarian cancer in 06, 1212, surgery and chemo paxitaxtel/carboplatin. In remission. Recurrence treated with tamoxifen, carboplatin alone, abraxan, then topotacan to no avail. Which chemo next?
Many options: Choosing chemo depends on many factors, so only your doctor can decide what might work for you. Drugs you haven't mentioned include altretamine, capecitabine, cytoxan, (cyclophosphamide) vinorelbine, ifosfamide, etoposide, and irinotecan. There are also several hormonal agents. And a clinical trial might be an option. Check out www.Cancer.Gov for more info. And good luck. ...Read moreSee 1 more doctor answer
Will avastin (bevacizumab) increase survival significantly for metastic colon cancer with liver mets ?
Is it a risky drug
Slight benefit: Bevacizumab (Avastin (bevacizumab)) is one of those drugs that is extremely expensive and often has limited benefit. Patients with metastatic colon cancer who received Avastin (bevacizumab) plus chemotherapy lived 1-2 months longer on average than those receiving chemo only. Because it has marginal benefit but costs ~$30,000 the U.K. Health Service won't pay for it. It can cause skin rash, bleeding or wound healing problems. ...Read more
Which treatment is better for Prostate cancer - Stage 1? Surgery for prostate removal or Radiation therapy with some medication?
Work w/ your Dr: This is worth discussing w/ your Dr or getting a 2nd opinion. They spent years building a knowledge base and also have examined you! Some research finds it less beneficial alone than in combo: http://www.ncbi.nlm.nih.gov/pubmed/24560487 But talk about your case w/ your team. ...Read more
Yes: Breast cancer is treated by stage but consideration is made to performance status not just age. So if the disease requires radiation even the elderly can usually tolerate the treatment. Stage 1 patients who have positive receptors may be able to omit the radiation if they are over 70 if they take hormone pills. ...Read moreSee 1 more doctor answer
Yes, it can be an op: This pill is often used in Japan. So it is not popular in the US. Moreover, it is better to be treated with a combination of 2 or 3 medicines that are proven useful in the treatment of metastatic colon Cancer. I would advise you to seek a second opinion so that you can make sure that your treatment is not substandard. ...Read more
Very good palliation: Y90 microspheres are very good at relieving pain or progression of liver metastasis from colon primaries. While this may improve survival chemotherapy addresses the disease in other parts of the body. Y90 is infused specifically into the liver and associated with good efficacy whith few side effects. ...Read moreSee 2 more doctor answers
Pancreatic cancer, ampullary tumor. Whipple procedure. Spread to liver, not respectable. Chemo for 6 months and continuing. Prognosis?
Poor: While Whipple is the best approach for a primary pancreatic or ampullary lesion, the recurrence rate at 1-2 yrs is 90%. Chemo either of the FOLFIERI or Genciabine /Abraxane combo have limited effects on liver mets which in pancreas are not considered amenable to resection. There is an FDA protocol using specific monoclonals targeting pancreas that might be available but only after chemo failure ...Read more
Energy beams: For certain types of colorectal cancer, energy beams are focused in the cancerous area. These beams are designed to kill cancer cells and decrease the chance of the tumor growing back. Depending on the situation, radiation can be used either before an operation or after an operation. ...Read moreSee 1 more doctor answer
Partially: Chemotherapy in all of its forms is only partially helpful in improving the survival of colon cancer. When there is an effective neoadjuvant response the remaining lesion can be successfully resected. complete surgical extirpation is the needed result. As immunochemo becomes more effective then the combination with surgery will even produce better results. ...Read more
Same drugs as other: Same chemotherapy drugs are used for treating both types of colon cancer. The only difference is lack of benefit from EGFR inhibitors(Cetuximab and Panitumumab). Avastin (bevacizumab) also works in both types. I trust that you know there are 3 chemo drugs that are widely used(5FU or Capecitabine, Irinotecan and Oxaliplatin) ...Read more
Yes: Radiation is standard treatment for rectal cancers which have not spread and is used in combination with chemotherapy. For pure colon cancers, radiation is used sometimes in special situations (e.g. Cancer involving nearby critical organ or causing pain/ bleeding). The main therapies for colon cancer though are surgery and chemotherapy. ...Read moreSee 1 more doctor answer
Can any targeted therapies or other drugs help with metastic colon cancer when Xeloda (capecitabine) n irinotecan has failed ?
Yes: Target agents that have activity either as single agent or as combination for recurrent or refractory metastatic colon cancer as a second line include: Avastin (bevacizumab) or Cetuximab/Panitumumab (if k-ras, n-ras, b-raf are wide type) or Regorafenib (inhibitor of angiogenic receptor) or aflibercept. FOLFOX may be effective too after irinotecan has failed. Clinical trials are aslo available. ...Read more
3 cycles of chemotherapy so far for metastic colon cancer shows therapy working , if 2 cycles are missed due to ill health , will cancer start growing agsin ?
No: If 3 cycles of chemo given and well tolerated, evaluation might show stability or regression if drugs working. If missing 2 cycles, this will not allow further regression while off medication, but if resumed a further response may be defined. Most combo drugs for colon cancer may show a termporary response but not cure. The newer combinations with Immunochemotherapy more effective. ...Read moreSee 2 more doctor answers
Yes: In some universities and major institutions there are dedicated machines for intraoperative radiation given to an area of concern that the surgeon could not resect and this device is aimed inside the abdomen to give the radiation. This is not common or widely available and outside machines are more readily available. ...Read moreSee 1 more doctor answer
Surgery+/-ChemoRx: The cornerstone of therapy is surgical resection of the part of the colon. The stage of the cancer is dependent upon the surgical findings (depth of cancer, lymph node evaluation), which will guide the decision regarding chemotherapy. Very rarely, radiation therapy will be recommended for more advanced colon cancers. ...Read moreSee 2 more doctor answers
Many: Colon cancer is so common that many medical trials have been performed which help doctors know better how to treat this disease. Depending upon the patient and stage of cancer, surgery, radiation, and various chemotherapies may be of benefit. You oncology team who know your specific situation can give more specific recommendations. ...Read moreSee 1 more doctor answer
Many options: Colon cancer is best treated in a multidisciplinary fashion according to location and stage at diagnosis. Most treatments are iv, but several oral agents are used as part of treatment regimens including Capecitabine (xeloda), and some targeted agents in trials. Treatment in early stages or selected patients with stage IV disease also involves surgery and may involve radiation. ...Read moreSee 2 more doctor answers
Depends: This depends on so many things, where it is, how invasive, what type of cancer, metastasis, patient health, etc. I do not mean to make light of it any way and I hope you are not dealing with it. While some may have successful treatments, it is very hard to say on any prognostic factors without a lot of detail in this specific circumstance. I know this does not clarify much, but hope it helps. ...Read moreSee 1 more doctor answer
Why do people become upset when i say if i get colon cancer im most likely going to refuse treatment?
If have stage 3b colon cancer and refuse to do port treatment and will only do pills how does it affect your chances?
A central IV port is no big deal. Regardless of the stats, why toss out this option (a mainstay of Rx) even before giving it a try? Please remember this can be a really nasty disease and I'd like to see you fight it with all you've got. I would hate to have you regret tying one hand behind your back years from now.
I personally have been fighting cancer for 20 years and I like the challenge. ...Read more
Surgery and ? chemo: The first step is to remove the tumor and lymph nodes to see if tumor has spread to these. Since you know it is stage iii this must have already be done. We know in patients with the disease spread to nodes around the tumor, it is more likely to recurr. The addition of chemotx reduces this risk. Talk to an oncologist about the risks and benefits of the chemo. Most patients should recieve it. ...Read moreSee 2 more doctor answers
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