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Doctor insights on: Colon Cancer Stage Iii

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Is stage 4 colon cancer terminal ?

Is stage 4 colon cancer terminal ?

Not good, but: Each person is unique. Discss this question w/ the doctors involved in treatment. It's not good, but there are certainly cases that will do better than others. All life ends. Stage 4 cancer is quite advanced and life expectancy is shortened significantly. Overall health can matter a lot for how long and how good. ...Read more

Dr. Barry Rosen
4,214 doctors shared insights

Cancer (Definition)

Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more


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Can a person live up to 5 years does it make a difference if you were diagnosed stage IV colon cancer than if were stage III but now hav a liver met?

No diff: The prognosis of someone diagnosed today with a liver metastasis of a colon cancer diagnosed a few years ago is not different from that of someone presenting today with newly diagnosed liver mets and primary colon cancer. Five year survival is not the rule, unfortunately, but I have seen many patients whose life exceeded five years after such a diagnosis. Treatment is improving rapidly. ...Read more

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Psych? Colon cancer 1/09 stage III surg. & chemo. Tiny liver met 2/12 stage iva liver resection. Horrible anxiety & h a. Pet scan in 2 wks. prescription .5mg clonezapam 2x's day. Fear ca's return. How to cope?

Psych? Colon cancer 1/09 stage III surg. & chemo. Tiny liver met 2/12 stage iva liver resection. Horrible anxiety & h a. Pet scan in 2 wks. prescription .5mg clonezapam 2x's day. Fear ca's return. How to cope?

Colon cancer: Confronting ones own mortality and living with a cancer that can and often recurs causes tremendous anxiety and depression. You are not alone. Unfortunately, many wonderful, talented, and smart people are confronting the same fate. Look into support groups and treatment with a psychiatrist to help you cope with this detour in life. ...Read more

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Stage iii-b colon cancer removed surgically. Suspected liver lesion resected and analyzed with not malignancy. Is kras analysis needed for recurrence?

Stage iii-b colon cancer removed surgically. Suspected liver lesion resected and analyzed with not malignancy. Is kras analysis needed for recurrence?

Possibly: For initial treatment after surgery, you shouldn't need to get kras testing. However, if this is metastatic or recurrent colon cancer, then it may help to determine if egfr based therapies like Cetuximab can help (they only work for kras "wild type"). Remember that if you do recur (god forbid), management may be different at that future time! not something to worry about with your current story. ...Read more

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In stage III colon cancer what is the significance of spread to 2 of 17 lymph nodes? What are lymph nodes?

In stage III colon cancer what is the significance of spread to 2 of 17 lymph nodes?
What are lymph nodes?

Significant: Cancers spread by either blood vessels or lymphatic pathways. Lymph nodes are collections of tissue along the lymphatic pathways, and are common places for tumor particles to start to grow. Your oncologist can discuss it in detail as to other measures you need to take, such as chemotherapy, radiation, more surgery, or some combination of all of the above. ...Read more

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For a stage iii-c colon cancer, can the chemotherapy considered curable? And is the chemo given for 6 months regional or systemic?

Yes: Stage iii-c colon cancer has a high chance of coming back due to the number of lymph nodes involved. That being said, there is a fighting chance of preventing recurrence with chemo so yes, it is still potentially curable. Chemo is usually systemic, a combo such as folfox (5fu, leucovorin, and oxaliplatin). Best to you. ...Read more

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For a stage III b colon cancer removed surgically, why the chemo should be systemic rather than regional although there are no metastasis?

For a stage III b colon cancer removed surgically, why the chemo should be systemic rather than regional although there are no metastasis?

Micrometastasis: The goal of adjuvant therapy is the eradication of occult micrometastatic tumor cells before metastatic disease becomes clinically evident. Undetected micrometastases can contribute to the failure of primary treatment. Adjuvant chemotherapy for stage iii colon cancer dramatically improves both relapse-free and overall survival. ...Read more

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For a 30 year female patient diagnosed with stage iii-b colon cancer, what are the expected specific rather than general side effects of folfox?

Depends on person: Folfox is a combination of chemo drugs, including oxaliplatin and Fluorouracil (5fu), and leucovorin and varies a bit by how and when they are given. The side effect profile includes suppression of bone marrow function, neuropathy (numbness or tingling), GI symptoms, fatigue, hair loss, mouth sores, , rash, and others. Individuals will experience varying degrees and types of side effects. ...Read more

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What is msi analysis? When and why it should be done for a stage iii-c colon cancer patient before chemotherapy?

What is msi analysis? When and why it should be done for a stage iii-c colon cancer patient before chemotherapy?

Lynch Syndrome: "microsatellite instability" examines if there are defects in gene repair pathways causing cancer. Some of these can be hereditary, and may influence other treatments (such as hysterectomy for endometrial cancer risk in females). Recently, msi status has been used to predict benefit from chemo, although this has been more important for stage ii patients. Talk to your doctor for details! ...Read more

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I have stage III colon cancer with 2 lymph nodes involved. I was too weak to go through chemo, but now after 6 months, am I sure to get it again?

I have stage III colon cancer with 2 lymph nodes involved. I was too weak to go through chemo, but now  after 6 months, am I sure to get it again?

Maybe not.: Although having disease in the lymph nodes increases the risk the disease is floating in the blood (which is why chemotherapy is effective in improving survival as it kills disease everywhere-including the blood) the relapse rate for stage 3 disease untreated is not 100%. You may still beat it. I would suggest speaking with an oncologist to see if treatment now would be of benefit. ...Read more

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Dr. Eric Kaplan
921 doctors shared insights

Colon Cancer (Definition)

Final few yards of your intestine, between the terminal ileum (small bowell) and rectum. It squeezes water and solidifies waste to stool. It is subject to outpouching (divertics) polyps, and these can become cancers. The cells are abnormal, invade into the muscle and travel ...Read more


Dr. Warren Foster
1 doctor shared a insight

Colon (Definition)

The colon is another term for the large intestine. This is the final portion of the digestive system, responsible for absorbing water and storing stool before evacuation. It is divided into sections described as cecum; ascending, transverse, descending and ...Read more