Doctor insights on:
Colon Cancer Progression
No: The use of tumor markers has been approved for monitoring only. This holds true for the CEA's and Carbohyrate monoclonals such as Ca 19.9 and Ca 125. This is due to the fact that they are also affected by inflammatory changes as well as tumors arising in glandular tissue. If a dx of Ca is well established and the patient is treated with chemo, a drop in tumor marker level means response. ...Read moreSee 2 more doctor answers
Final few yards of your intestine, between the terminal ileum (small bowell) and rectum. It squeezes water and solidifies waste to stool. It is subject to outpouching (divertics) polyps, and these can become cancers. The cells are abnormal, invade into the muscle and travel ...Read more
Since on chemotherapy , each month in a row CEA rising as:
Colon cancer pt with a liver meta.is this progression ?
What can this mean . Before chemotherapy cea was 65, after 1 round 80 and after 2 round 55 for metastic colon cancer ?
Units?: Given that u r from England, the units for the CEA test may be different there. In the US, a level less than 5 ng/mL is "normal". CEA is used as a tumor marker (i.e., colon cancer likely), but (to my knowledge) is not very useful as an indicator of response to treatment. U describe incomplete treatment, anyways. After finishing the rounds of chemotherapy, then check the CEA- that may b useful. ...Read moreSee 2 more doctor answers
What kills a person in metastic colon cancer . Does the liver have to fail or can the mets alone cause death ?
Many ways: The actual mechanism varies. The liver or the cancer itself can get infected. Even small lung metastasis can cause pneumonia, or the overall debility from the cancer can cause this. Deep thrombi are one of several more common ways. Biliary obstruction is more common than actual liver failure. Bowel obstruction can hopefully be prevented by your surgeon. ...Read moreSee 2 more doctor answers
What can this cea pattern mean on chemotherapy for colon cancer mets
65 before chemo, 80 after round 1, 55 after round 2?
It's improving!: All it really means is the CEA is going in the right direction ... falling after chemotherapy. You can not reliably speculate on what the number changes might say about the magnitude of improvement. There is too much individual variability and unpredictability for that. I would be pleased that these changes have occurred. Best wishes as you continue your treatment:) ...Read moreSee 1 more doctor answer
Not always reliable: I assume that from ALP you meant Alkaline Phosphatase(a type of liver function test). But avoid using abbreviations. This test can sometimes be correct in showing tumor progression but we need more information than this test alone in order to assess tumor response. The additional tests that help are measuring the liver size , checking CEA level(Blood test) and for making final decision, CT scan. ...Read more
Can you successfully treat a recurrent colon cancer? This is my mothers third time.Had all lymph nodes removed after first surgery i
Colon cancer: It appears your mother's colon cancer has been recurrent over a period of years, meaning it is not likely to cure her microscopic disease. That said, her disease can be managed for as long as individual foci can be targetted and more widespread disease cannot be controlled. There is no exact timeline on that, but regular follow up with her doctors should monitor her status/control/progression. ...Read moreSee 1 more doctor answer
Very good palliation: Y90 microspheres are very good at relieving pain or progression of liver metastasis from colon primaries. While this may improve survival chemotherapy addresses the disease in other parts of the body. Y90 is infused specifically into the liver and associated with good efficacy whith few side effects. ...Read moreSee 2 more doctor answers
Only in lab cells: Alpha lipoic acid is a potent antioxidant that has typically been used for diabetic neuropathy. Current "in vitro" studies suggest that colon cancer cells grown in the lab, self-destruct (apoptosis) in the presence of alpha-lipoic acid. At least one patient claimed to be cancer-free after using ALA. ALA is non-toxic but difficult to find in a pure form.Choose foods instead-spinach, broccoli ! ...Read moreSee 1 more doctor answer
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