Top
20
Doctor insights on: Colon Cancer Pathophysiology

Share
1

1
Is colon cancer genetic?

Is colon cancer genetic?

Sometimes: Some colon cancers are related to specific genetic mutations but the majority are not. ...Read more

See 1 more doctor answer
Dr. Barry Rosen
4,344 doctors shared insights

Cancer (Definition)

Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more


2

2
Large intestinal cancer. Is that colon cancer?

Large intestinal cancer. Is that colon cancer?

Yes: The large intestine and the colon are words to describe the same anatomic structure in the abdomen. ...Read more

3

3
Is metastatic colon cancer curable?

Is metastatic colon cancer curable?

Possible: But less than 20% survive 5 years. Depends on where the metastases are and how numerous and size. Solitary liver mets without evidence elsewhere in the body can be cured with a liver resection. Diffuse mets to numerous body parts rarelyare curable. ...Read more

See 1 more doctor answer
4

4
What causes colon cancer?

Very complicated: Monoclonal theory says that just like we are a living thing, we are born, we have jobs to do and then we die, each cell has a similar cycle of birth, life, and death. Cancer occurs when a cell develops so many mutations that it does not follow that cycle and does not die but can still divide itself and hides from our immune system which is there to detect abnormal cells and destroy them. ...Read more

See 1 more doctor answer
5

5
Is colon cancer curable?

Is colon cancer curable?

Yes: Yes. Many people are cured with colon cancer. If found early surgery alone may be curable. If more advanced (eg, lymph node involvement or metastatic = spread to areas outside of colon), then chemotherapy may be needed. While less likely, even a few % of people with metastatic colon ca may be cured. ...Read more

See 2 more doctor answers
6

6
Why is the colon prone to cancer in hnpcc (hereditary nonpolyposis colorectal cancer)?

Why is the colon prone to cancer in hnpcc (hereditary nonpolyposis colorectal cancer)?

Genetic mutations: HNPCC or hereditary nonpolyposis colorectal cancer is an autosomal dominant genetic condition that has a high risk of colon cancer The disease first described by Lynch and is associated with other cancers including endometrial ovary and stomach. The increased risk is due to inherited mutations that impair DNA mismatch repair. .Individuals with HNPCC have an 80% lifetime risk for colon ca. ...Read more

7

7
Is colon cancer fatal?

Is colon cancer fatal?

Not Necessarily: It depends on the stage at diagnosis and the treatment obtained. ...Read more

See 1 more doctor answer
8

8
Are carcinoid tumors carcinoma? Is malignant metastatic stomach carcinoma that's hereditary a carcinoid cancer? carcinoid Neuroendocrine tumors?

Are carcinoid tumors carcinoma? Is malignant metastatic stomach carcinoma that's hereditary a carcinoid cancer? carcinoid Neuroendocrine tumors?

Complicated question: Carcinoids are carcinomas, usually more slow growing than adenocarcinomas. For information in this topic you may consult this link: http://www.webmd.com/cancer/carcinoid-tumors#1 ...Read more

9

9
What stage of colon cancer is polyp?

What stage of colon cancer is polyp?

Pre-cancerous: Polyp only means a grape like structure protruding into the lumen of an organ. Some cancers appear polypoid. Histologically confirmed benign polyp, by a pathologist, is a pre-cancerous lesion. ...Read more

See 2 more doctor answers
10

10
Is bowel cancer hereditary?

Is bowel cancer hereditary?

Somehow yes: There is some genetic predisposition in families with hx. Of colorectal cancer. Diet also plays a rol ( low fiber diet increases cancer). Familiar poliposis increases chances of colon cancer. Colon polyps may degenerate in cancer. Small intestine cancers are rare and difficult to find. In general there are families affected by cancers and families affected by atherosclerosis but both together too. ...Read more

See 1 more doctor answer
11

11
Is colon cancer and olvarian cancer often related?

Is colon cancer and olvarian cancer often related?

No: Colon Cancer is induced for the most part in non hereditary disease by viral transfection. The most common organism is the polyoma virus. Ovarian cancer is not derived from this viral event. Colon cancer begins in the mucosa of the bowel where ovarian Ca is an epithelial disease similar to that of peritoneal carcinomatosis. The only relationship is when colon metastasizes to ovary. ...Read more

See 2 more doctor answers
12

12
Are breast cancer and colon cancer linked?

Are breast cancer and colon cancer linked?

Not directly usually: There is debate about how closely these 2 cancers are related. Both have hereditary natures and are more common generally in obese patients. Both often begin with more benign precursor lesions like dcis for breast cancer and benign polyps for colon cancer. Both are very common but there is little evidence that having either predisposes to having the other. ...Read more

See 2 more doctor answers
13

13
Colon cancer or colorectal cancer, what's the difference?

Colon cancer or colorectal cancer, what's the difference?

Location: Cancers that arise from the epithelium of the large intestine are similar in most ways whether they are in the colon or rectum. Discussions of "colon cancer" unspecified usually mean "colorectal" unless stated otherwise. Usage, including by me, is often sloppy. ...Read more

14

14
How are colon cancer and intestinal cancer different?

How are colon cancer and intestinal cancer different?

Can be the same: The intestines are a group of structures including stomach, small intestine and large intestine (which is the colon). Cancers can form in any of these sites, but large intestine (colon) cancer is most common. So colon cancer is a type of intestinal cancer. ...Read more

See 2 more doctor answers
15

15
Colorectal cancer causes?

Colorectal cancer causes?

Heredity & diet: The cause is not known in most cases. In a small number the cause is clearly heredity, e.g., apc and hnpcc. In the garden variety colon cancer, a diet low in fiber and rich in fats may increase the risk of cancer. ...Read more

16

16
Is colon cancer fast-growing?

Is colon cancer fast-growing?

Can be: The fastest-growers are the ones that follow genetic pathways associated with the lynch loci. They may not even be preceded by a polyp -- colonoscopy can be clean one year, and a year later, there's a cancer. That's actually quite fast as cancers go. Hope this helps. ...Read more

See 1 more doctor answer
17

17
Is colon cancer preventable?

For the most part.: Early detection via colonosocpy, not ignoring symptoms such as bleeding, change in bowels, anemia, unintentional weight loss, and not assuming all rectal bleeding is from hemorrhoids are some ways to reduce your chances and maybe prevent colon cancer from developing. ...Read more

See 1 more doctor answer
19

19
Is bowel cancer genetic?

Is bowel cancer genetic?

Sometimes: Some colon cancers are related to inheritable genetic mutations but the majority are not. ...Read more

See 1 more doctor answer
20

20
Is pancreatic cancer genetic?

Is pancreatic cancer genetic?

A minority is.: Pancreatic adenocarcinoma, arising from ducts/epithelial tissue, is mainly "sporadic", but can run in families. Pancreatic cancer has also been related to brca mutation, fammm syndrome, and some other inherited conditions. The familial pancreatic cancer registry is at johns hopkins. A minority of neuroendocrine tumors of the pancreas are associated with multiple endocrine neoplasia (men) syndromes. ...Read more

See 1 more doctor answer
Dr. Lynne Weixel
13 doctors shared insights

Colon (Definition)

The colon is another term for the large intestine. This is the final portion of the digestive system, responsible for absorbing water and storing stool before evacuation. It is divided into sections described as cecum; ascending, transverse, descending and ...Read more


Dr. Thomas Inwood
12 doctors shared insights

Colonic (Definition)

This is a combining term referring to some condition, treatment or disease of the colon. Such as colonic enema, colonic ...Read more