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Doctor insights on: Colon Cancer Metastasis To Liver And Lung Prognosis

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My mum, 67, was diagnosed with colon cancer with liver metastases, lesions in lungs and kidneys. Starting folfox tomorrow?? Life expectancy?

My mum, 67, was diagnosed with colon cancer with liver metastases, lesions in lungs and kidneys. Starting folfox tomorrow?? Life expectancy?

Not enough: Need to assess for Kras and Nras mutation IF she is wild type she should receive FOLFIRI and Erbitux

If she has mutation the treatment of choice FOLFOX and Avastin

Life expex 22 – 26 months... If responsive disease can be extended with other agents and survival can extend several years.

New agents add to OS sequencing of therapy is important to extend Overal survival ...Read more

Dr. Barry Rosen
4,351 doctors shared insights

Cancer (Definition)

Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more


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Chances of metastasis to lung of stage II colon cancer?

Chances of metastasis to lung of stage II colon cancer?

Low but not zero: Stage ii colon cancer means no lymph node involvement by definition, but inadequate lymph node sampling (surgical resection) may "understage" the cancer, so make sure enough ln were taken -minimum of 12! Even with appropriate surgery, mets may still occur, although very unusual, so discuss with your treating docs. A pet/ct may give some reassurance so ask if this can be done. ...Read more

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Why is colon resection still done for colon cancer in cases with liver metastasis?

Why is colon resection still done for colon cancer in cases with liver metastasis?

Depends: Believe it or not, it can sometimes still be cured. It depends on the disease burden in the liver. After resection, they can do adjuvant therapy and follow up with hepatic resections if it is limited.

Also, for palliative reasons — if it is causing an obstruction, then the obstruction needs to be relieved to allow for simple gut function. ...Read more

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Is liver metastases from colon cancer a death sentence?

Is liver metastases from colon cancer a death sentence?

It could be commuted: Until recently, colon cancer metastases in the liver were invariably fatal within a few years. However, there are some new biotechnology findings that suggest this may no longer always be the case. Your oncologist would be the person to ask. ...Read more

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What's survival like for colon cancer pt with a liver metastases and an aortocaval node? Years approximation plz

What's survival like for colon cancer pt with a liver metastases and an aortocaval node? Years approximation plz

1-2 yrs: If liver mets present then the aortocaval node should be considered to be part of overall treatment. First use of FOLFIERI chemo and then evaluation for resection should be contemplated. A single aortocarval node easily resected before chemo. If liver lesions treatable by resection or microwave ablation this should be tried. Followed by chemoembolization if needed. ...Read more

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Is in case of colon cancer with liver metastases (and during chemoth) recommended a specific diet? Are there any anti cancer food? What about turmeric

Is in case of colon cancer with liver metastases (and during chemoth) recommended a specific diet? Are there any anti cancer food? What about turmeric

Not really.: It all depends on the symptoms. Chemo can affect the taste, alter your bowel habits, and decrease appetite. The goal is to stay well hydrated. High fiber diet may help with both constipation or diarrhea. There is no specific "anti cancer"diet that you can go on. No significant data available to support turmeric in the foods. ...Read more

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What is prognosis like for colon cancer pt with 1 liver met, 1 node and 0.5 lung nodule? Primary was resected last year. Cea 10. Bloodwork normal?

What is prognosis like for colon cancer pt with 1 liver met, 1 node and 0.5 lung nodule? Primary was resected last year. Cea 10. Bloodwork normal?

Prognosis: Prognosis is determined at time of diagnosis/treatment. Seems cancer is/was stage 4, which has a shorter prognosis than stage 1. If stage 4 is NEW, newly discovered liver metastasis, then prognosis will be negatively impacted compared to a year ago. Regardless of prognosis, talk with your docs. Take friend/family with you to appointments to help with understanding. Treatments exist. Be well. ...Read more

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My mother has stage IV colon cancer that has mestitized to the liver. She has 15 tumors in liver with spots in her lungs and lymph nodes. Prognosis?

My mother has stage IV colon cancer that has mestitized to the liver. She has 15 tumors in liver with spots in her lungs and lymph nodes. Prognosis?

Stage IV colon cance: Your mohter's cancer is stage iv.

Please refer to the table on this page for survival data:

http://www.Cancer. Org/cancer/colonandrectumcancer/detailedguide/colorectal-cancer-survival-rates

I am so sorry to hear that you are going through this terrible time. ...Read more

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What are the chances of surviving colon cancer that has spread to liver, kidney and lungs?

What are the chances of surviving colon cancer that has spread to liver, kidney and lungs?

Poor: When one finds metastasis to multiple sites from a primary colon cancer the lesion was probably detected late in its development. If the patient is in good condition the primary if not resected should be removed. Chemo with FOLFOX and possibly avastin (bevacizumab) should be attempted. Kidney lesions are extremely rare but can respond to chemo and if causing complication should be resected. ...Read more

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Colon cancer with cancer in liver, lungs sacrum and spine?

Colon cancer with cancer in liver, lungs sacrum and spine?

Stage of cancer: This sounds very serious. Cancer is staged to help understand the treatments and expectations for success with treatment, part of the risk/benefit analysis. Stage 4 is cancer that has spread or progressed significantly outside the organ where it started. Stage 1, 2, 3 and 4 have diminishing expectations for treatment success. Take a friend with you to next appointment. You have choices. Be well. ...Read more

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Is it possible to cure stage IV colon cancer that has limited number of mets to lung and liver?

Is it possible to cure stage IV colon cancer that has limited number of mets to lung and liver?

Hmmmm: You know, the terms "stage iv" and "cure" are not usually put in the same sentence by oncologists because in theory, most stage IV cancers are incurable. That said, I have seen a handful of patients who had a limited number of metastases to the liver or lung and are in remission years later after aggressive surgery and chemo. Don't lose hope. Best wishes. ...Read more

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What is the life expectancy of a 78-year old, Stage 4 colon cancer spread to liver and lungs? Having chemotherapy (tablets) but losing weight.

What is the life expectancy of a 78-year old, Stage 4 colon cancer spread to liver and lungs? Having chemotherapy (tablets) but losing weight.

Life expectancy: At 78, with stage IV colon cancer, the survival is about 4-6 months without treatment. With the new treatments combining chemo with biological drugs, survival times are in the range of 24-30 months. With a less aggressive treatment I estimate an AVERAGE survival of 9-12 months. Keep in mind these estimates are just a ball park figure, keep things one month at a time. ...Read more

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My uncl has colon cancer that has spread to his liver and now his lungs. He also has CHF and had half of his colon removed. What is his survival rate?

My uncl has colon cancer that has spread to his liver and now his lungs. He also has CHF and had half of his colon removed. What is his survival rate?

Unfortunately: Not too much, not in years, make him comfortable, now the quality of life is important I end stage cancer disease, not just the patient, family also must participate in the decisions. ...Read more

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If chemotherapy fails, and there is a tiny new lung nodule, 1 liver met and 1 node can anything b done in colon cancer pt aged 65?

If chemotherapy fails, and there is a tiny new lung nodule, 1 liver met and 1 node can anything b done in colon cancer pt aged 65?

Sometimes: Depending on co-morbidities and surgical risk, some studies have shown survival benefit with surgical resection of metastatic lesions. Consult with cancer surgeon. ...Read more

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Colon cancer 3yrs ago. Surgery, 2spots was in liver. Chemo for 2yrs. Now z tumor is 15 cm& 7.5 wiz spots in lungs!fatigue &dysfunction liver. What help?

Colon cancer 3yrs ago. Surgery, 2spots was in liver. Chemo for 2yrs. Now z tumor is 15 cm& 7.5 wiz spots in lungs!fatigue &dysfunction liver. What help?

NCI: It does not seem as though surgery is an option for you at this time. Body-wide treatment such as chemotherapy is going to be the preferred way to treat this. Seek care at a national cancer institute designated comprehensive cancer center. This will give you the best access to available clinical trials. Another option is to go to the website www.Cancer. Gov and click in the clinical trial link! ...Read more

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Life expectancy of previously never sick, active healthy 67 year old after colon cancer surgery +12 rounds chemo, 6 months later spread to liver&lung?

Life expectancy of previously never sick, active healthy 67 year old after colon cancer surgery +12 rounds chemo, 6 months later spread to liver&lung?

Your best bet: Is to review a question like this with your medical oncologist. There are many factors that contribute to survival statistics and you want to make sure you're being provided with accurate information. This requires a more complete understanding of your medical/oncologic history. ...Read more

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Father got diagnosed w/ stage 4 colon cancer. Spread to liver, lungs, and brain. Currently at city of hope. Recommend a good place in LA areas? Help!

Father got diagnosed w/ stage 4 colon cancer. Spread to liver, lungs, and brain.  Currently at city of hope. Recommend a good place in LA areas? Help!

Here R some options: City of Hope is a good Cancer Center. Alternative institutions include USC- Cancer Center, UCLA cancer Center and many oncologists in private practice. Search under Medical Oncologists in your area and make a call/s to find out if another medical oncologist would accept your father for treatment of his metastatic Colon cancer. This is a disease for which good treatments are available ...Read more

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If chemotherapy treatment fails for metastic colon cancer pt, what else can be done for a liver met, 1 node and a tiny lung nodule?

If chemotherapy treatment fails for metastic colon cancer pt, what else can be done for a liver met, 1 node and a tiny lung nodule?

Remove lung lesion: At age 34 attempt at cure should be made. If liver met small and primary already out, liver met to be resected or microwave ablated. Usually chemo is only of temporary value and if all fails, the FDA protocol for monoclonal antibody Neo102 is available for treatment of metastatic colon cancer having failed chemo. The small node and lung lesion can be removed by laparoscopy/thoracoscopy. ...Read more

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Can anything b done for a liver met, 1 lung nodule and a lypmph node if chemo fails? Does this mean no treatment for colon cancer pt?primary removed

Can anything b done for a liver met, 1 lung nodule and a lypmph node if chemo fails? Does this mean no treatment for colon cancer pt?primary removed

Metastatic colon CA: Typically, metastatic cancer (cancer that has spread to organs/areas beyond where it started) is considered incurable. There are some exceptions; if colon cancer has a single metastasis to the liver OR a lung, then chemotherapy & surgical removal of the met might be successful (perhaps 50%). For more than one organ, chances are less, & treatment frequently shifts towards comfort if chances poor/none. ...Read more

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Pain in left side & abnormal BM for month- liver, lungs, blood, urine, endoscopy, kidneys, gall bladder, lungs, heart, all ok — possible colon cancer?

Pain in left side & abnormal BM for month- liver, lungs, blood, urine, endoscopy, kidneys, gall bladder, lungs, heart, all ok — possible colon cancer?

Here are some ...: For the time being, watch for possible food indigestion. Besides, continue to watch for possible colonic diverticulitis. Note that every illness always displays itself along its course & pattern of full spectrum. So, still seek professional attention & counseling timely. Don't give up; time & patience will unfold the true story of an event timely. ...Read more

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What is the icd-9 code for metastasis colon cancer and the cpt code to?

What is the icd-9 code for metastasis colon cancer and the cpt code to?

Need more info: The code for colon cancers is 153._. 153.9 is for colon cancer of unspecified site. There is a separate group of codes for metastasis and the site. The number after 153 is for the site of the primary tumor.
I can't answer the cpt code question, because there is not enough information. ...Read more

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For a stage III b colon cancer removed surgically, why the chemo should be systemic rather than regional although there are no metastases?

For a stage III b colon cancer removed surgically, why the chemo should be systemic rather than regional although there are no metastases?

Micrometastasis: The goal of adjuvant therapy is the eradication of occult micrometastatic tumor cells before metastatic disease becomes clinically evident. Undetected micrometastases can contribute to the failure of primary treatment. Adjuvant chemotherapy for stage iii colon cancer dramatically improves both relapse-free and overall survival. ...Read more

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In metastic colon cancer do the size and number of metastases matter?

In metastic colon cancer do the size and number of metastases matter?

Yes: In colon cancer as with most malignancies as the lesion increases in size the greater the population of mutated cells with varying surface glycoproteins defining different sites of metastasis. With the metastasis alreadyu present each of these cells express a mutated form of mitochondrial DNA acting as immunogenic inhibitory molecules making treatment more difficult. ...Read more

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Can an aortocaval node be cured / treated which has metastases? It's 10 mm in size in a colon cancer pt where primary is removed

Can an aortocaval node be cured / treated which has metastases? It's 10 mm in size in a colon cancer pt where primary is removed

Yes: In removing what is considered a solitary metastatic focus and in particular a lymph node, one must make sure the lesion is solitary. A PET/CAT scan will resolve this issue and if solitary should be removed by surgical resection. If other sites noted then chemo followed by surgery should be performed. ...Read more

Dr. Ana Adelstein
2 doctors shared insights

Liver (Definition)

This organ plays a major role in metabolism and has a number of functions in the body, including glycogen storage, decomposition of red blood cells, plasma protein synthesis, hormone production, and detoxification. It lies below the diaphragm in the abdominal-pelvic region of the abdomen. It produces bile, an alkaline compound which aids in digestion via the emulsification of ...Read more


Lung (Definition)

Deoxygenated blood enters the lungs from the right side of the heart and travels to the lungs. When you inspire, oxygen flows into the lungs, transverses the capilliares and attaches to hemoglobin down a gradient. At the same time, co2 diffuses into the capilaries and is expelled with exhalation. Oxygen rich blood then flows to the left side of the heart and into the ...Read more