Doctor insights on:
Colon Cancer Metastasis Sign Fatigue
For a stage III b colon cancer removed surgically, why the chemo should be systemic rather than regional although there are no metastasis?
Micrometastasis: The goal of adjuvant therapy is the eradication of occult micrometastatic tumor cells before metastatic disease becomes clinically evident. Undetected micrometastases can contribute to the failure of primary treatment. Adjuvant chemotherapy for stage iii colon cancer dramatically improves both relapse-free and overall survival. ...Read moreSee 1 more doctor answer
A cancer begins in an organ (say the breast). If it gets into the blood stream or the lymphatic stream the cells can travel to other parts of the body where, in the right environment, they may settle and grow. This development of tumor growth far away from the original site ...Read more
Depends: Believe it or not, it can sometimes still be cured. It depends on the disease burden in the liver. After resection, they can do adjuvant therapy and follow up with hepatic resections if it is limited. Also for palliative reasons - if it is causing an obstruction, then the obstruction needs to be relieved to allow for simple gut function. ...Read moreSee 1 more doctor answer
Low but not zero: Stage ii colon cancer means no lymph node involvement by definition, but inadequate lymph node sampling (surgical resection) may "understage" the cancer, so make sure enough ln were taken -minimum of 12! even with appropriate surgery, mets may still occur, although very unusual, so discuss with your treating docs. A pet/ct may give some reassurance so ask if this can be done. ...Read moreSee 1 more doctor answer
Yes: In colon cancer as with most malignancies as the lesion increases in size the greater the population of mutated cells with varying surface glycoproteins defining different sites of metastasis. With the metastasis alreadyu present each of these cells express a mutated form of mitochondrial DNA acting as immunogenic inhibitory molecules making treatment more difficult. ...Read more
Can a aortocaval node be cured / treated which has metastases
? It's 10 mm in size in a colon cancer pt where primary is removed
Yes: In removing what is considered a solitary metastatic focus and in particular a lymph node, one must make sure the lesion is solitary. A PET/CAT scan will resolve this issue and if solitary should be removed by surgical resection. If other sites noted then chemo followed by surgery should be performed. ...Read more
What's survival like for colon cancer pt with a liver metastases and a aortocaval node? Years approximation plz
1-2 yrs: If liver mets present then the aortocaval node should be considered to be part of overall treatment. First use of FOLFIERI chemo and then evaluation for resection should be contemplated. A single aortocarval node easily resected before chemo. If liver lesions treatable by resection or microwave ablation this should be tried. followed by chemoembolization if needed. ...Read more
It could be commuted: Until recently, colon cancer metastases in the liver were invariably fatal within a few years. However, there are some new biotechnology findings that suggest this may no longer always be the case. Your oncologist would be the person to ask. ...Read moreSee 2 more doctor answers
Is there a difference in prognosis being diagnosed with stage 4 colon cancer and being diagnosed stage 3
And then liver metastases was found on scan ?
Liver: metastases would indicate stage 4 disease.Get a more detailed answer ›
Final few yards of your intestine, between the terminal ileum (small bowell) and rectum. It squeezes water and solidifies waste to stool. It is subject to outpouching (divertics) polyps, and these can become cancers. The cells are abnormal, invade into the muscle and travel ...Read more
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