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Doctor insights on: Colon Cancer Lymph Node Metastasis

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After resection of colon cancer with few lymph node involvement, what next?

After resection of colon cancer with few lymph node involvement, what next?

Chemotherapy: So stage 3 disease or lymph node involvement needs adjuvant chemotherapy. I also like to get a baseline ct scan of the abdomen and pelvis. The standard chemotherapy would be a regimen called folfox which is folinic acid, 5-fu, and oxaliplatin. The treatment is given every 2 weeks for 12 treatments or 6 months. Hope this helps. ...Read more

Dr. Barry Rosen
4,344 Doctors shared insights

Cancer (Definition)

Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more


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If chemotherapy fails what options lfd metastic colon cancer? Mets to liver, peritoneal, lymph node?

If chemotherapy fails what options lfd metastic colon cancer? Mets to liver, peritoneal, lymph node?

Experimental therapy: Some cancer centers do research on patients with aggressive cancers or cancers who do not respond to usual treatment.

Although after chemotherapy, there are not very many options and people would like to keep patients as comfortable as possible.

Hope it is helpful. ...Read more

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What's survival like for colon cancer pt with a liver metastases and a aortocaval node? Years approximation plz

What's survival like for colon cancer pt with a liver metastases and a aortocaval node? Years approximation plz

1-2 yrs: If liver mets present then the aortocaval node should be considered to be part of overall treatment. First use of FOLFIERI chemo and then evaluation for resection should be contemplated. A single aortocarval node easily resected before chemo. If liver lesions treatable by resection or microwave ablation this should be tried. Followed by chemoembolization if needed. ...Read more

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What is the icd-9 code for metastasis colon cancer and the cpt code to?

What is the icd-9 code for metastasis colon cancer and the cpt code to?

Need more info: The code for colon cancers is 153._. 153.9 is for colon cancer of unspecified site. There is a separate group of codes for metastasis and the site. The number after 153 is for the site of the primary tumor.
I can't answer the cpt code question, because there is not enough information. ...Read more

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Chances of metastasis to lung of stage II colon cancer?

Chances of metastasis to lung of stage II colon cancer?

Low but not zero: Stage ii colon cancer means no lymph node involvement by definition, but inadequate lymph node sampling (surgical resection) may "understage" the cancer, so make sure enough ln were taken -minimum of 12! even with appropriate surgery, mets may still occur, although very unusual, so discuss with your treating docs. A pet/ct may give some reassurance so ask if this can be done. ...Read more

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For a stage III b colon cancer removed surgically, why the chemo should be systemic rather than regional although there are no metastasis?

For a stage III b colon cancer removed surgically, why the chemo should be systemic rather than regional although there are no metastasis?

Micrometastasis: The goal of adjuvant therapy is the eradication of occult micrometastatic tumor cells before metastatic disease becomes clinically evident. Undetected micrometastases can contribute to the failure of primary treatment. Adjuvant chemotherapy for stage iii colon cancer dramatically improves both relapse-free and overall survival. ...Read more

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Why is colon resection still done for colon cancer in cases with liver metastasis?

Why is colon resection still done for colon cancer in cases with liver metastasis?

Depends: Believe it or not, it can sometimes still be cured. It depends on the disease burden in the liver. After resection, they can do adjuvant therapy and follow up with hepatic resections if it is limited.

Also for palliative reasons - if it is causing an obstruction, then the obstruction needs to be relieved to allow for simple gut function. ...Read more

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Can a aortocaval node be cured / treated which has metastases? It's 10 mm in size in a colon cancer pt where primary is removed

Can a aortocaval node be cured / treated which has metastases? It's 10 mm in size in a colon cancer pt where primary is removed

Yes: In removing what is considered a solitary metastatic focus and in particular a lymph node, one must make sure the lesion is solitary. A PET/CAT scan will resolve this issue and if solitary should be removed by surgical resection. If other sites noted then chemo followed by surgery should be performed. ...Read more

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Is liver metastases from colon cancer a death sentence?

Is liver metastases from colon cancer a death sentence?

It could be commuted: Until recently, colon cancer metastases in the liver were invariably fatal within a few years. However, there are some new biotechnology findings that suggest this may no longer always be the case. Your oncologist would be the person to ask. ...Read more

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In metastic colon cancer do the size and number of metastases matter?

In metastic colon cancer do the size and number of metastases matter?

Yes: In colon cancer as with most malignancies as the lesion increases in size the greater the population of mutated cells with varying surface glycoproteins defining different sites of metastasis. With the metastasis alreadyu present each of these cells express a mutated form of mitochondrial DNA acting as immunogenic inhibitory molecules making treatment more difficult. ...Read more

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Is in case of colon cancer with liver metastases (and during chemoth) recommended a specific diet? Are there any anti cancer food? What about turmeric

Is in case of colon cancer with liver metastases (and during chemoth) recommended a specific diet? Are there any anti cancer food? What about turmeric

Not really.: It all depends on the symptoms. Chemo can affect the taste, alter your bowel habits, and decrease appetite. The goal is to stay well hydrated. High fiber diet may help with both constipation or diarrhea. There is no specific "anti cancer"diet that you can go on. No significant data available to support turmeric in the foods. ...Read more

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My mum, 67, was diagnosed with colon cancer with liver metastases, lesions in lungs and kidneys. Starting folfox tomorrow?? Life expectancy?

My mum, 67, was diagnosed with colon cancer with liver metastases, lesions in lungs and kidneys. Starting folfox tomorrow?? Life expectancy?

Not enough: Need to assess for Kras and Nras mutation IF she is wild type she should receive FOLFIRI and Erbitux

If she has mutation the treatment of choice FOLFOX and Avastin

Life expex 22 - 26 months... If responsive disease can be extended with other agents and survival can extend several years.

New agents add to OS sequencing of therapy is important to extend Overal survival ...Read more

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In stage III colon cancer what is the significance of spread to 2 of 17 lymph nodes? What are lymph nodes?

Significant: Cancers spread by either blood vessels or lymphatic pathways. Lymph nodes are collections of tissue along the lymphatic pathways, and are common places for tumor particles to start to grow. Your oncologist can discuss it in detail as to other measures you need to take, such as chemotherapy, radiation, more surgery, or some combination of all of the above. ...Read more

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Can you successfully treat a recurrent colon cancer? This is my mothers third time. Had all lymph nodes removed after first surgery I

Colon cancer: It appears your mother's colon cancer has been recurrent over a period of years, meaning it is not likely to cure her microscopic disease. That said, her disease can be managed for as long as individual foci can be targetted and more widespread disease cannot be controlled. There is no exact timeline on that, but regular follow up with her doctors should monitor her status/control/progression. ...Read more

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Does colon cancer spread to neck if lymph nodes are negative?

Very unlikely: Colon cancer that does not involve lymph nodes should not have neck lymph node involvement. If you recently had surgery you probably had a central catheter placed in your neck for IV administration. This may be the lump you are feeling. Make sure you talk to your doctor at the next visit to have a look. You could also have swelling from the endotrachral tube. ...Read more

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Is colon cancer stage 3b pt4a pn1c, no lymph nodes involvement curable?

Is colon cancer stage 3b pt4a pn1c, no lymph nodes involvement curable?

Yes: Stage 3b usually means lymph nodes are involved, so I think your information might not be entirely accurate. However, even stage 3b colon cancer can be treated with surgery and chemotherapy and the chances of cure are good. ...Read more

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Colon cancer: pathology report says pt4a pn1c. And it also says no lymph nodes involved, how could that be?

Colon cancer: pathology report says pt4a pn1c. And it also says no lymph nodes involved, how could that be?

Not in lymph nodes: In general, the 'N' of a tumor staging report refers to involvement of lymph nodes, and anything that isn't 'N-0 (zero)' usually means there are lymph nodes involved by tumor. However, 'N' staging is different for every organ site. In the colon, the N1c stage specifically refers to there being tumor deposits in the fat outside of the colon wall, but not in the lymph nodes themselves. ...Read more

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What does n1c means in colon cancer? What does it mean depostits of tumor but without lymph nodes involvement

What does n1c means in colon cancer? What does it mean depostits of tumor but without lymph nodes involvement

Characteristics: These are all characteristics we use to determine the aggressiveness of a cancer.

These dictate to us, if and which chemotherapy should be used and other treatments and follow ups accordingly.

The features you describe should all warrant a consultation with an oncologist. ...Read more

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What are typical colon cancer symptoms that most patients have? Do all cancer patients have swollen, painful lymph nodes?

What are typical colon cancer symptoms that most patients have? Do all cancer patients have swollen, painful lymph nodes?

Here are some. ..: Does this question pertain to you? If yes, it is much less likely happening to one at 20. The common symptoms related with colon cancer are changed habit of BM without traceable foods indigestion, bloody in or on stool, but most patients would not have any symptoms at all in its early stage. Besides, it related LN enlargement presents in mesentery, not outside. More? Ask doctors timely. ...Read more

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My husband had a colon tumor removed they got it all but has stage 3 colon cancer 6 of 20 lymph nodes what does this mean?

My husband had a colon tumor removed they got it all but has stage 3 colon cancer 6 of 20 lymph nodes what does this mean?

An excellent website: I am sorry to hear your news. You obviously have been going through a lot. The nih has an excellent, patient friendly website with info about this. See:

http://www.Cancer.Gov/cancertopics/pdq/treatment/colon/patient/page2

the site goes on to discuss treatment. He is most likely looking at chemotherapy. Your oncologist should be able to help with the details. Good luck to you both. ...Read more

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Why are tumor deposits in colon cancer considered as lymph nodes when there are no lymphovascular invasion, because of td it's becoming a stage 3?

Why are tumor deposits in colon cancer considered as lymph nodes when there are no lymphovascular invasion, because of td it's becoming a stage 3?

Local spread: If the tumor deposits are located away from the main primary, then most authorities consider them to be equivalent to a positive lymph node (s). Most likely these deposits got there via lymphovascular invasion even if the pathologist could not see that histologically on the slides. The ajcc also considers discontinous tumor deposits as n1c in the pathological staging system. ...Read more

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I think I might have colon cancer. Is it possible for colon cancer to spread to the lymph nodes in my neck? If so how likely? I'm 18 years old. Female

I think I might have colon cancer. Is it possible for colon cancer to spread to the lymph nodes in my neck? If so how likely? I'm 18 years old. Female

Not Very Likely: Given your age it is highly unlikely you have colon cancer. Major factors that increase the risk of colon cancer include family history, age, and inflammatory bowel disease. Most common cause of swollen lymph nodes in neck are a recent viral or bacterial infection. See your doctor if you are concerned or have concerning gastrointestinal complaints. ...Read more

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How quickly colon cancer is spreading from lymph nodes to other organs?

Highly variable: Each person is different and there is no set time or schedule where colon cancer may or may not spread to lymph nodes or to other organs. Some small colon cancers will spread early and other cancers will grow large and not spread. ...Read more

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How fast can colon cancer be spreading from lymph nodes to other organs?

How fast can colon cancer be spreading from lymph nodes to other organs?

It is relative.: This depends upon the stage of cancer at diagnosis. Colon cancer is staged by the dukes' system. Stages a and b have no lymph mode involvement and so no spread is likely. Stage c patients do better if <5 nodes are involved so those are likely to be slower than those with >5 nodes. Stage d means distant metastasis (organs involved). It is hard to say since people come in at diferent stages. ...Read more

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What type and stage could be predicted of a colon cancer that is around 8 CM and not spread to lymph nodes?

Stage 1 or 2: A colon cancer that is confined to the bowel wall, irrespective of size is stage 1 or formerly duke's a. If it grows through the bowel wall, it is stage 2 or the old duke's b. If lymph nodes are involved, it is stage 3 or the old duke's c. Stage 4 or the old duke's d has spread to distant sites. Your described case could be stage 1 or 2. ...Read more

Metastasis (Definition)

A cancer begins in an organ (say the breast). If it gets into the blood stream or the lymphatic stream the cells can travel to other parts of the body where, in the right environment, they may settle and grow. This development of tumor growth far away from the original site ...Read more


Dr. Gregory Moneta
13 Doctors shared insights

Colon (Definition)

The colon is another term for the large intestine. This is the final portion of the digestive system, responsible for absorbing water and storing stool before evacuation. It is divided into sections described as cecum; ascending, transverse, descending and ...Read more