Doctor insights on:
Colon Cancer Generally Develop
From polyps usually: Almost all colon cancers start off as a polyp, hence the push for colonoscopy screening looking for polyps. Only 20% of colon cancers are hereditary, meaning the rest are environmentally related to foods we eat and chemicals we are exposed too. If you are over 50 or have risl factors get regular colonoscopies. ...Read moreSee 1 more doctor answer
Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more
No: Colon Cancer is induced for the most part in non hereditary disease by viral transfection. The most common organism is the polyoma virus. Ovarian cancer is not derived from this viral event. Colon cancer begins in the mucosa of the bowel where ovarian Ca is an epithelial disease similar to that of peritoneal carcinomatosis. The only relationship is when colon metastasizes to ovary. ...Read moreSee 2 more doctor answers
Genetic mutations: HNPCC or hereditary nonpolyposis colorectal cancer is an autosomal dominant genetic condition that has a high risk of colon cancer The disease first described by Lynch and is associated with other cancers including endometrial ovary and stomach. The increased risk is due to inherited mutations that impair DNA mismatch repair. .Individuals with HNPCC have an 80% lifetime risk for colon ca. ...Read more
Can be the same: The intestines are a group of structures including stomach, small intestine and large intestine (which is the colon). Cancers can form in any of these sites, but large intestine (colon) cancer is most common. So colon cancer is a type of intestinal cancer. ...Read moreSee 2 more doctor answers
What percentage of lynch syndrome patients develop colon polyps by age 60? Not cancer but just polyps
Colon ca, not polyps: Lynch syndrome affects a minority of patients, as it is a rare condition that is often inherited (in about 30% of pts). Of these pts, about 70% will develop colon cancer - most of them by age 60. The risk is high. But the syndrome causes NON-polyp colon cancer, not polyps. It usually requires colon removal (colectomy) to reduce risk. Use HealthTap Prime or talk to your gastroenterologist about sym ...Read more
For what reason colon part is usually prone to cancer in hnpcc (hereditary hereditary nonpolyposis colorectal cancer)?
Mutations: There are many theories. One is that cancer is often the result of several mutations in cells that occur over time. It may take several of these mutations over time to cause cancer. Another is that certain cell growth control systems get inactivated over the years. This is call epigenetic change. Also over time more environmental exposures take their toll. Age allows more of these thing to happe. ...Read moreSee 1 more doctor answer
Does having gallbladder removed increase risk of colon cancer? Or does gallbladder removal cause colon cancer?
What % can colon cancer return with ulcerative colitis after cancer tumor is removed from that part of colon ?
High risk of cancer: Recurrence risk given cancer is a function of the stage of cancer when diagnosed, independent of uc. However, uc patients have an approximately 1% per year risk of new cancer appearing. Because of this high risk, total colectomy has been the standard of care for uc. If you have any colon left, it should be examined and biopsied periodically looking for dysplasia, the precursor of cancerous change. ...Read moreSee 2 more doctor answers
Sometimes: There is a familial disorder known as lynch syndrome which increases both the risk of colon cancer and endometrial (uterine) cancer. About 5% of all colon cancers are caused by lynch syndrome. If a family has multiple cases of both colon and endometrial cancer or colon cancer under the age of 40, lynch syndrome should be considered. ...Read moreSee 1 more doctor answer
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