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Doctor insights on: Colon Cancer Chemotherapy Regimen

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How effective is the IFL chemotherapy regimen for treating colon cancer?

How effective is the IFL chemotherapy regimen for treating colon cancer?

It is an old regimen: It is one of the effective treatment regimens for metastatic colon Cancer which first appeared on the scene more than 5 years back and became popular for a while to be soon upgraded with other more effective modern regimens which also include Avastin (bevacizumab) in combination with chemotherapy. ...Read more

Dr. Barry Rosen
4,223 doctors shared insights

Cancer (Definition)

Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more


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How effective is the XELOX chemotherapy regimen for treating colon cancer?

How effective is the XELOX chemotherapy regimen for treating colon cancer?

Relatively good: According to the Journal of Clinical Oncology XELOX is a highly effective first-line treatment for metastatic colon cancer. To be more accurate (55%) of patients achieve a response, and 30% experience disease stabilization for more than 3 months following treatment. Always consult with your oncologist. ...Read more

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How effective is the FOLFIRI chemotherapy regimen for treating colon cancer?

How effective is the FOLFIRI chemotherapy regimen for treating colon cancer?

Some effect: Single drug chemotherapy has failed to produce significant improvement in colorectal Ca. Combination chemo as in FOLFIRI with irinotecan has added about 5 month prolongation in survival and with immunotherapy using Avastin (bevacizumab) or Erbitux an additional 2-3 months can be observed. Chemo-Immuno with a mAb targeting the immunogenic protein appears to be giving further enhancement. ...Read more

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How effective is the IFL-Bevacizumab chemotherapy regimen for treating colon cancer?

How effective is the IFL-Bevacizumab chemotherapy regimen for treating colon cancer?

Better than chemo: Combining bevacizumab (BV)—a recombinant, humanized mAb targeting VEGF with irinotecan, fluorouracil (FU), and leucovorin (LV; IFL) has increased survival of patients with metastatic colorectal Ca compared with IFL It appears necessary to use combination therapy in treatment and has supported the concept that the use of immunochemotherapy improves results over chemo alone. ...Read more

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How effective is the FOLFIRI-Bevacizumab chemotherapy regimen for treating colon cancer?

How effective is the FOLFIRI-Bevacizumab chemotherapy regimen for treating colon cancer?

Moderately useful: FOLFIRI-Bev is the standard, commonly used first line chemotherapy for metastatic Colon cancer. It can add about 12 to 18 months extra to your life such that an average patient can live for 2 to 3 years(some live upto 5-6 years... depending on sites of metastases and their response to chemotherapy. You need tell us more about your history such as dates of diagnosis and treatments/results so far?? ...Read more

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What can my mother expect who has colon cancer and will be on the folfox 4 regimen for chemotherapy?

What can my mother expect who has colon cancer and will be on the folfox 4 regimen for chemotherapy?

It depends: Results depend upon the stage of cancer. It is active for the adjuvant treatment and in metastatic disease. The side effects can include nausea and diarrhea. Occasionally there can be some blood count issues. The other side effect can be cold related temporary nerve injury that lasts a very short time. There also is a more long term nerve injury. Most people do tolerate this well. Hope this helps. ...Read more

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How effective is chemotherapy for treating colon cancer?

How effective is chemotherapy for treating colon cancer?

Improves survival: Chemo may help improve survival but does not result in cure. It is used pre operatively as neo adjuivant chemo to help improve resection or as adjuvant after surgery to help prolong survival. It is best employed in combination chemo such as FOLFOX to optimize response. ...Read more

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I am getting chemotherapy for colon cancer. Is the dose normally increased with each round?

I am getting chemotherapy for colon cancer. Is the dose normally increased with each round?

Ask your oncologist: That's an interesting question. It would depend on the regimen you were on, so ask your oncologist at your next visit. He/she can describe dosage , complications, and general expectations. Good luck. ...Read more

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If colon cancer was there several can chemotherapy actually cause cancer to spread ? As all was fine before chemo ( no distant spread ) ?

If colon cancer was there several can chemotherapy actually cause cancer to spread ? As all was fine before chemo ( no distant spread ) ?

Cancer metastatisis: It's very unlikely that chemotherapy would cause your cancer to spread. Chances are micro metastatic disease existed earlier and has just now become evident. Speak with your doctor. ...Read more

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Dysphagia and chemotherapy for colon cancer?

Dysphagia and chemotherapy for colon cancer?

It depends ... : Dysphagia is a common side effect with many chemo therapeutic regimens. Some treatments can decrease a patient's ability to fight off fungal and bacterial overgrowth in the mouth and digestive systems. The diagnosis of this isn't usually difficult and can in many cases be treated with medications. ...Read more

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Dr. Eric Kaplan
923 doctors shared insights

Colon Cancer (Definition)

Final few yards of your intestine, between the terminal ileum (small bowell) and rectum. It squeezes water and solidifies waste to stool. It is subject to outpouching (divertics) polyps, and these can become cancers. The cells are abnormal, invade into the muscle and travel ...Read more


Dr. John Landi
1 doctor shared a insight

Colon (Definition)

The colon is another term for the large intestine. This is the final portion of the digestive system, responsible for absorbing water and storing stool before evacuation. It is divided into sections described as cecum; ascending, transverse, descending and ...Read more