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Doctor insights on: Colon Cancer And Wnt Pathway

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What % can colon cancer return with ulcerative colitis after cancer tumor is removed from that part of colon ?

What % can colon cancer return with ulcerative colitis after cancer tumor is removed from that part of colon ?

High risk of cancer: Recurrence risk given cancer is a function of the stage of cancer when diagnosed, independent of uc. However, uc patients have an approximately 1% per year risk of new cancer appearing. Because of this high risk, total colectomy has been the standard of care for uc. If you have any colon left, it should be examined and biopsied periodically looking for dysplasia, the precursor of cancerous change. ...Read more

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Dr. Barry Rosen
4,344 doctors shared insights

Cancer (Definition)

Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more


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Is liver resection possible for brother w/stage 4 colon cancer mest to liver w/lots of tumor.

Is liver resection possible for brother w/stage 4 colon cancer mest to liver w/lots of tumor.

Possibly: Removal of liver metastases can sometimes be helpful for patients with colon cancer. A remarkable amount of cancer can be removed usually after there has been some response to chemotherapy. If surgery is not recommended alternatives such as radioembolization, chemoembolization, radiosurgery, or rfa or cryoablation may be considered. Get with an experienced team to determine the best course! ...Read more

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How to slow down the growth of cancer cells? (for last stage cancer patient, cancer cells at liver, lung and pelvis. Most critical is liver.)

How to slow down the growth of cancer cells? (for last stage cancer patient, cancer cells at liver, lung and pelvis. Most critical is liver.)

Your Oncologist can: This is a broad question. There are many anticancer drugs that are used to slow cancer cell growth. But they vary in their effectiveness depending on which organ is the source of cancer. Not knowing the details of the history i can not be any more specific. Please pose this question to the treating oncologist. ...Read more

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Signet rng cell adenoc. Tumor in stomach blcking of pyloric canal remvd. Lymph nodes of immediate neg to de minimis for cancer. Prtn neg. Slight breach of tumor to colon. What test to see if spread?

Signet rng cell adenoc. Tumor in stomach blcking of pyloric canal remvd. Lymph nodes of immediate neg to de minimis for cancer. Prtn neg. Slight breach of tumor to colon. What test to see if spread?

PET/CT.. beware ...: Pet/ct scan is often used to stage cancers however it is important to note that signet ring cell adenocarcinoma of the stomach is often not FDG avid and has been known to cause false negative results on pet. ...Read more

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My dad died of cancer that spread from his lip to lymph nodes to lung 47yo, gpa died of prostate cancer 79yo. Any studies linking cancer to genetics?

My dad died of cancer that spread from his lip to lymph nodes to lung 47yo, gpa died of prostate cancer 79yo. Any studies linking cancer to genetics?

There are: There are several cancers that area related to genetics. The are about 5-15% of cancers. The bulk are not. In your case the key question is if your father was a smoker or not. This kind of cancer is not usually related to prostate cancer. The other important thing is that your mother's family history also is equally important as your father's. ...Read more

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Pancreatic cancer. Whipple. Chemo 7 months. Tumors in pancreas and liver. Recent blood clot. Pain. New intestinal blockage. Is my body shutting down?

Pancreatic cancer. Whipple. Chemo 7 months. Tumors in pancreas and liver. Recent blood clot. Pain. New intestinal blockage. Is my body shutting down?

Difficult disease: Some blockages are due to scar tissue inside the abdomen (called adhesions), and other blockages are due to cancer growth. A CT scan may be able to tell the difference between the 2. If the blockage is cancer-related, then it may be time to think about a different chemotherapy regimen. But if it's just adhensions, then sometimes an operation helps. Talk to your doctor to investigate further ...Read more

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Can pancreatic/biliary duct, stomach, colon cancer or leukemia skip a generation?

Can pancreatic/biliary duct, stomach, colon cancer or leukemia skip a generation?

Variable: Family incidence doesn't mean you will have the disease only that you MAY get it and should be more vigilant. For example colon cancer. Start colonoscopy at age 30 rather than 50, etc.. ...Read more

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Does the brca2 gene also cause colon cancer? Or just breast and ovarian?

Does the brca2 gene also cause colon cancer? Or just breast and ovarian?

BRCA for breast: Brca genetic mutations are for breast and ovarian cancers , for for colonic cancers apc gene, & familial non polyposis gene mutation are tested. 75% of colon cancers has no family history, best way to detect early is by regular doctor visits and colonoscopic examinations for early detection and cure. ...Read more

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Help please! is colon cancer and bile duct cancer basically the same thing?

Help please! is colon cancer and bile duct cancer basically the same thing?

Completely different: Colon cancer originates in the colon. Bile duct cancer originates in the bile ducts either within the liver or in the parts of the bile duct system outside of the liver (common hepatic and common bile ducts). ...Read more

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Does colon cancer metastasize to the breasts?

Anything: Is possible, but this is very unlikely. Colon cancer usually metastasize to liver, lungs, or sometimes brain. ...Read more

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What is the relationship between colon cancer and prostate cancer?

What is the relationship between colon cancer and prostate cancer?

Genetic conditions: There are certain genetic mutations where prostate cancer and colon cancer can manifest at an increased incidence. However most cases of colon cancer and prostate cancer are spontaneous. ...Read more

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Mom=cancer mets in lungs and liver. Prim tumor squamous cell in sm bowel. Chemo july to dec. Starting chemo again this week- can tocotrienals help?

Mom=cancer mets in lungs and liver. Prim tumor squamous cell in sm bowel.  Chemo july to dec. Starting chemo again this week- can tocotrienals help?

Tocotrienols and CA: Tocotrienols are vitamin-e related chemicals called tocopherols and, as such, are powerful antioxidants which are known to have a wide variety of salubrious effects on blood vessel and skin integrity, and have been shown in many studies to have some positive effects on some cancers, although i cannot find any literature related to colon cancer. Check with her md about taking these with her meds. ...Read more

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Is colon cancer and olvarian cancer often related?

Is colon cancer and olvarian cancer often related?

No: Colon Cancer is induced for the most part in non hereditary disease by viral transfection. The most common organism is the polyoma virus. Ovarian cancer is not derived from this viral event. Colon cancer begins in the mucosa of the bowel where ovarian Ca is an epithelial disease similar to that of peritoneal carcinomatosis. The only relationship is when colon metastasizes to ovary. ...Read more

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My 63 yr old mom w/ colon cancer, stge 4, is on folfox. Multiple chemo's have failed to shrink or slow down the cancer. Is folfox better/any other?

Avastin (bevacizumab): Folfox or folfiri seem to be the best agents for advance colorectal cancer. In some patients the addition of Avastin (bevacizumab) can be added in some patients. I would expect her oncologist has discussed these options. ...Read more

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How can we find colon cancer through stool test?? What are the symptoms of colon cancer??

How can we find colon cancer through stool test?? What are the symptoms of colon cancer??

Here are few thought: Colon Cancer is often a silent disease in its early stages. That is why a colonoscopy examination is advised at the age of 50 years.
Some people will present with rectal bleeding(Blood in the stools). Abdominal pain and anemia related symptoms(fatigue) can also be a signal of colon cancer. Stool tests(2 of them) are also available through your PCP. ...Read more

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Mum has large mass (colorectal cancer mestasis to lung) in her lung that is pushing up against her esophagus. No more Chemo. Life expectancy?

Mum has large mass (colorectal cancer mestasis to lung) in her lung that is pushing up against her esophagus. No more Chemo. Life expectancy?

Approx 1 yr.: An assumption that primary has been resected. As such what is in lung will stay in lung. With esophageal compression, tube feedings may be used for nourishment. Then if FOLFIERI not used should be employed followed by drugs like Erbitux, Avastin, (bevacizumab) Zaltrap and when these fail may be candidate for monoclonal Neo102 followed by Neo 201. ...Read more

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Dysphagia and chemotherapy for colon cancer?

Dysphagia and chemotherapy for colon cancer?

It depends ... : Dysphagia is a common side effect with many chemo therapeutic regimens. Some treatments can decrease a patient's ability to fight off fungal and bacterial overgrowth in the mouth and digestive systems. The diagnosis of this isn't usually difficult and can in many cases be treated with medications. ...Read more

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Why is colon resection still done for colon cancer in cases with liver metastasis?

Why is colon resection still done for colon cancer in cases with liver metastasis?

Depends: Believe it or not, it can sometimes still be cured. It depends on the disease burden in the liver. After resection, they can do adjuvant therapy and follow up with hepatic resections if it is limited. Also for palliative reasons - if it is causing an obstruction, then the obstruction needs to be relieved to allow for simple gut function. ...Read more

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My mom has stage 4 colon cancer that spread to most of her intestines. Will radiation treatment help her?

No RT: Radiation therapy is not employed in metastatic colon cancer. Its most frequently employed in large rectal or rectosigmoid tumors with chemo to shrink the tumor in preparation for surgery. Metastatic stage 4 colon cancer is treated by combination chemo with immunotherapy i.e. FOLFIERI + ZALTRAP ( an epidermal growth factor inhibitor) New monoclonals are also in FDA trials for stage 4 colon Ca. ...Read more

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Can this be colon cancer?

Not enough info: Colon cancer can present with or without symptoms. Common symptoms include change in stool caliber/consistency, rectal bleeding or blood with bm, abdominal pain, anemia. If you have not been screened, you should consider the various screening options for colon cancer, includine a stool test to check for blood, colonoscopy, or sigmoidoscopy. If you are having bleeding, you need a colonoscopy. ...Read more

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How to know if colon cancer ?

How to know if colon cancer ?

Get tested: There are many tests that have been developed to test either a patient with concerning symptoms or just as a routine screening exam in an a symptomatic patient. Each individual situation is different. Testing stool for blood or now genetic abnormalities, rectal exam, X-rays such as barium enema or ct scan virtual colonoscopy are examples. Best is colonoscopy as you can both look and do. ...Read more

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What is the cause of colon cancer?

What is the cause of colon cancer?

Multiple factors: Age over 50, chronic intestinal diseases, polyps, diabetes, smoking, sedentary lifestyle, heavy alcohol consumption and filly history of cancer can all increase your risk. Majority occur due to acquired defects in cells lining the intestines from a combination of one or more factors. Small minority are hereditary. ...Read more

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How to know if I have colon cancer?

Colonoscopy: Colonoscopy + biopsy as indicated. If you do have risk factors, you should have your first screening colonoscopy at age 50. ...Read more

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What are the stages of colon cancer?

What are the stages of colon cancer?

1 through 4: The stage of colon cancer is based upon the depth of penetration of the cancer thru the colon wall, the presence or absence of lymph node involvement, and the presence of cancer elsewhere in the body (metastatic disease). The stage is associated with prognosis and guides our recommendations regarding chemotherapy. ...Read more

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What sort of disease is colon cancer?

What sort of disease is colon cancer?

Cancer: Colon cancer is a cancer of the large intestine (colon). Surgery is generally required to remove the portion of colon involved with cancer. Colonoscopy is performed to prevent colon cancer. Polyps, small growths, , which can turn into cancer, are removed during a colonoscopy so they don't turn into a cancer. ...Read more

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What are the symptoms of colon cancer

What are the symptoms of colon cancer

None at early stage: Early stage of colon cancer has no symptoms at all , that is the reason to have colonascopy, at the age of 50 and on, . Early detection assures the cure, as tumor advances change of bowel habit, bleeding, weight loss, bowel obstruction etc. ...Read more

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What is the symptoms of colon cancer?

What is the symptoms of colon cancer?

More than one sympto: The symptoms are different/varied in each person. Rectal bleed is a common symptom. A change of bowel habits(constipation alternating with diarrhea), weight loss and abdominal pain are relatively common symptoms. What is your age??? ...Read more

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What stage colon cancer is pt4a pn1c?

T4aN1c M?: Any evidence of spreading to other organ? If no spread- t4an1 means- stage 3b cancer. If evidence of sprading to other organ- it is a stage 4. ...Read more

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What is the symptoms for colon cancer?

What is the symptoms for colon cancer?

Colon Cancer: Possible Sx's /Signs of colon cancer: Blood in stool, change in feces (loose stool/ constipation/ etc.), abdominal pain, cramps, gas, weight loss, weakness, incomplete evacuation of bowel. See: http://www.mayoclinic.org/diseases-conditions/colon-cancer/basics/symptoms/con-20031877 ...Read more

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Dr. Que Chu Dr. Chu
3 doctors agreed:
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What is the prevalence of colon cancer?

Dr. Que Chu Dr. Chu
3 doctors agreed:
What is the prevalence of colon cancer?

Colon Cancer: Review of literature shows: 132,700 new cases diagnosed each year in the US. 93,000 of these cases are colon cancer and the rest are rectal cancer. Colon and rectal cancer is common and lethal. Five years survival rate varies from 93% for stage I to 8.6% for stage IV. ...Read more

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What are the usual signs of colon cancer?

What are the usual signs of colon cancer?

Depends: Colon cancer sometimes presents with symptoms, but often has no symptoms until later. This is why getting regular screening colonoscopies is recommended. If symptoms are present they can include blood in the stool, weight loss, change in caliber of the stool. Abdominal pain is less common. Since this cancer grows from a small polyp into cancer slowly, be proactive & get regular colonoscopies! ...Read more

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What are the usual signs of colon cancer?

What are the usual signs of colon cancer?

Depend of location: Women and men are equally affected by colon cancer. The symptoms depend of the localization of the tumor in the right or the left colon. Family history is important. The right colon cancer can grows without symptoms, it presents with asthenia, weakness and when checked anemia will be present, in the left side cancer presents with progressive const.Ipation. Colonoscopy at 50 y.O find curable cancer. ...Read more

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How should I know if I have colon cancer?

Only way: To know for sure is by colonoscopy. If you are not in a high risk group and have no symptoms such as abdominal cramping, blood in stool, or anemia, your chances of colon cancer before age 50 is pretty low. Talk to your doctor about getting proper tests. ...Read more

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How to figure out if I have colon cancer?

How to figure out if I have colon cancer?

Colonoscopy: Over the age of 40 xolonoscopy every 5 yers is a good idea becuase colon cancer can be detected early and cured. Idead is to pick up polypoid lesion that has not invaded into muscularis. Other than for that the diagnosis in an asymptomatic patient is diffieucult. A new test is being developed to measure shed antigen into the stool. This occurs in the earliest lesion where no markers in blood. ...Read more

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Is it possible to have colon cancer at 18?

Very unlikely: Colon cancer typically starts after the age of 50, although due to obesity and other factors there is been a trend of increasing incidence in the younger groups. Even so, colon cancer is very unlikely at ages younger than 40. Even if one has the classical familial polyposis which is at a higher risk for colon cancer, the average age is still 39. ...Read more

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I am afraid that I could have colon cancer?

I am afraid that I could have colon cancer?

What are you...: ...waiting for??? You need to see a doctor. You may need a colonoscopy. We cannot diagnose you online. Best to you. ...Read more

Dr. Barbara Lavi
13 doctors shared insights

Colon (Definition)

The colon is another term for the large intestine. This is the final portion of the digestive system, responsible for absorbing water and storing stool before evacuation. It is divided into sections described as cecum; ascending, transverse, descending and ...Read more


Dr. Debra Rosenblatt
12 doctors shared insights

Colonic (Definition)

This is a combining term referring to some condition, treatment or disease of the colon. Such as colonic enema, colonic ...Read more