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Doctor insights on: Collagen Vascular Diseases Systemic Lupus Erythematosus Sle

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Systemic lupus erythematosus--what is sle?

Systemic lupus erythematosus--what is sle?

Autoimmune disease: A disease in which your body makes antibodies against your own cells. These antibodies cause destruction and inflammation which produce a wide variety of symptoms depending on what cells are being injured. There are some common symptoms and signs with the disease, but just about any symptom could be produced by lupus. ...Read more

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Collagen (Definition)

Collagen is a component of extracellular tissue, which is found throughout the body. Collagen is a proten important for tissue strength and tissue healing. There are several differnt subtypes of collagen, depending on where it is found. Collagen has a high content of hydroxyproline, which is ...Read more


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Is lupus erythematosus infectious?

No: Is a immune based disease does not recognize self and attacks multiple organs. ...Read more

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Is systemic lupus erythematosus fatal?

Sometimes.: Sle is generally treated with good response, but unfortunately it is sometimes fatal. ...Read more

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Which percentage of diagnosed lupus cases are sle, systemic lupus erythmatosus?

Lupus: Lupus comes in 4 major types: systemic, discoid (skin only), neonatal, and drug-induced. Some people who have an abnormality in their immune system and fail to make a body defense protein called complement are also at risk for developing lupus. It has been estimated that 1.5 million people in the US have one of these lupus forms. Women are 2-3 times more likely to develop this disease than men. ...Read more

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Dr. Alfred Kim Dr. Kim
2 doctors agreed:
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What gene causes lupus erythematosus?

Dr. Alfred Kim Dr. Kim
2 doctors agreed:
What gene causes lupus erythematosus?

Many genes: The previous answer is right with several genes associated with lupus, but no one knows how those genes cause disease. I think it's important to remember that there is likely many ways to develop lupus symptoms, and this will vary between people. So some of these known genes will be important for some, and not important for others. As we sequence more patients, we'll have more answers. ...Read more

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Atenolol-induced lupus erythematosus http://www.Ncbi.Nlm.Nih.Gov/pubmed/9270530?

Atenolol-induced lupus erythematosus           http://www.Ncbi.Nlm.Nih.Gov/pubmed/9270530?

Let me explain: I read the article, this medication could induce symptoms of autoimmune disease including lupus, but lupus has no cure to date but those symptoms disappear with the treatment. That the main difference. ...Read more

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How are systemic lupus erythematosus, coma & leukopenia related?

How are systemic lupus erythematosus, coma & leukopenia related?

SLE: Is a systemic disease and is a form of vascullitis, which means that there is inflammation in the blood vessels as a result it is a multi-system disease and can affect any organ in the body. When the brain is affected it can lead to changes in mood, psychosis and even coma. Leukopenia is a recognized feature of SLE at some point in the course of the disease. It can affect the kidneys, joints etc ...Read more

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Is systemic lupus erythematous contagious?

Is  systemic lupus erythematous contagious?

No: It is an autoimmune disease in which your body produces antibodies against your own body cells leading to organ damages if left untreated. It is not contagious. ...Read more

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Is lupus an autoimmune disease?

Is lupus an autoimmune disease?

Lupus: Lupus is a classic autoimmune disease that attacks cells, tissues and organs . It is a systemic auto immune disease that attacks skin, heart, lungs , liver, kidneys , blood vessels and nervous system. Anti body production by b cells are to dna , sm antigen, histones and other proteins of cell nucleus . Immune complex deposition in surfaces damage blood vessels in kidneys and other organs ...Read more

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Are discoid lupus and sle different?

Are discoid lupus and sle different?

Yes: Discoid lupus is confined to the skin while systemic lupus can affect literally any organ of the body including the skin. ...Read more

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What is trigger systemic lupus erythematosus in antiquity?

Mysterious lupus: It is not known what causes lupus erythematosus. Referring to antiquity, lupus was used to describe several different rashes. It could be autoimmune, where the body attacks itself such as lupus erythematosus or discoid lupus. It could be caused by tuberculosis infection such as lupus vulgaris. It could be related to another inflammatory disease such as sarcoidosis which causes lupus pernio. ...Read more

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Whats death rate related to systemic lupus erythematosis?

Whats death rate related to systemic lupus erythematosis?

Less now: In the 1950s, 60% of lupus patients died within five years. Now, more than 90% survive beyond five years. Many lupus patients have non-life threatening disease. Kidney or brain involvement portends a worse prognosis. ...Read more

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What autoimmune diseases mimic arthritis?

What autoimmune diseases mimic arthritis?

Many cause arthritis: Rheumatoid arthritis, lupus, and ankylosing spondylitis commonly cause arthritis. The joints are the target of many autoimmune diseases. ...Read more

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Why hydroxychloroquine is effective in treating systemic lupus erythematosus?

Why hydroxychloroquine is effective in treating systemic lupus erythematosus?

It is magic?: 1the use of anti-malarials in autoimmune diseases was accidentally discovered in treating wwii vets for malaria. Those with RA improved. Chloroquine and ho-q were tested in sle, with very positive results. In the early 80's canadian researchers definitively showed fewer sle flares with ho-q. It is considered the rx of first choice for :sle. We now understand more of the mechanisms, but not all. ...Read more

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What are some alternative therapies for sle (systemic lupus erythematosus)?

What are some alternative therapies for sle (systemic lupus erythematosus)?

None: Diet and omega 3 fatty acids may help but there are no specific vitamin or herbal supplements for sle. Avoiding sugar and dairy is helpful for some people. Omega three fatty acids along with vitamin c and b complex may reduce symptoms. ...Read more

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Dr. Christopher Bibb
53 doctors shared insights

Collagen Vascular Disease (Definition)

Collagen vascular disease was a term originally used to describe an abnormality of the collagen protein associated with blood vessels. It is now used to describe a collagen protein disorder in many types of connective tissues, ...Read more


Systemic (Definition)

A condition that involves the whole body as compared to a part of the body. For example diabetes ...Read more