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Doctor insights on: Collagen Vascular Diseases Soft Tissue Sarcoma

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Dr. Adam Lewis
2 doctors shared insights

Sarcoma (Definition)

By definition, it is malignant (i.e., being locally invasive and at least theoreticlally capable of metastasizing), and arises from / mimics muscle or connective tissue elements that are not marrow or immune / white cells. The sarcomas are a tremendously varied and troublesome family of tumors, though thankfully less common than carcinomas and the leukemia / ...Read more


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Is fibromatosis a soft tissue sarcoma?

Is fibromatosis a soft tissue sarcoma?

Yes: Fibromatosis, while it doesn't have "sarcoma"in the name is actually a low-grade sarcoma. However, this only applies to cases occurring in the abdomen. Less commonly, these tumors can occur on the extremity. Cases of Palmar and Plantar fibromatosis are not aggressive and generally behave in a benign fashion. Have your sarcoma pathology checked by an expert [email protected] ...Read more

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Whats mixed connective tissue disease?

Whats mixed connective tissue disease?

Labs can confuse.: The labs are just a fraction of what needed to get you better. Your history and physical exam will determine your treatment. Looking for which labs will delay and confuse. You need to develop a few paragraphs of all your issues and sit down with your doctor to put the pieces together. Began a wellness program and add in magnesium and acupuncture. ...Read more

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What is undifferentiated connective tissue disease?

What is undifferentiated connective tissue disease?

Type not clear: Undifferentiated connective-tissue disease (uctd) is a diagnosis applied to signs and symptoms that are consistent with a connective-tissue disease (ctd) but that do not fulfill the classification or diagnostic criteria for any one of the defined ctds such as (rheumatoid arthritis, lupus, etc..). ...Read more

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Is Mixed Connective Tissue Disease Hereditary?

Is Mixed Connective Tissue Disease Hereditary?

Partly: The exact cause of this disease is still unknown. We believe that there is a genetic or inherited predisposition and a second enviorental trigger for this disease. It is rate to see 2 family members with this disease. Basically this means it is not an inherited disease. The abity to get this disease may be inherited but not the disease itself. ...Read more

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What is a "connective tissue disease"? Had punch biopsy on rash, suggestive of early connective tissue disease. What is "connective tissue?"

What is a "connective tissue disease"? Had punch biopsy on rash, suggestive of early connective tissue disease. What is "connective tissue?"

Connective tissue: This is a constellation of disease affecting the supporting tissue throughout the body. It involves fat, cartilage,bone.there are different types with names such as Eleros Danlos , Marfans syndrome, Osteogensis imperfecta, they are all a result of gene dysfunction.ie are inheritable disorders. Most are fairly uncommon. The treatment varies depending on the specific areas involved ...Read more

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Is Palmar fibrosis a autoimmune disease or Mixed connective tissue disease?

Is Palmar fibrosis a autoimmune disease or Mixed connective tissue disease?

No: It's neither. It's an overgrowth of fibrous tissue that's poorly understood. Sometimes an injection can break it, or surgery's an option. Best wishes. ...Read more

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Is sle a connective tissue disease?

Is sle a connective tissue disease?

Yes: It is classified as aconnective tissue disease because it involves joints and soft tissue with inflammation along with rheumatoid arthritis, dermatomyosits, and mixed connective tissue disease. ...Read more

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What is mixed connective tissue disease?

What is mixed connective tissue disease?

Combination of CTD: Mixed connective tissue disease is an autoimmune conditions with a combination of autoimmune diseases systemic lupus erythematosus, rheumatoid arthritis, scleroderma and polymyositis. One of these conditions is usually more prominent than the others at one time and with time it can progress to the other autoimmune diseases. Thus you may have arthritis, or a rash, or internal medical probelm. ...Read more

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Does platelet rich plasma injections to ligaments cause scar tissue or new connective tissue?

Does platelet rich plasma injections to ligaments cause scar tissue or new connective tissue?

Both: Injecting platelet rich plasma is supposed to amplify the response of the repair cells by supplying growth factors to the area of injection. It's a good theory, but evidence of other than short term changes is lacking. ...Read more

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What is fibrocollagenous tissue and adipose tissue?

Good question: Fibrocollagenous tissue is the connective tissue throughout our bodies that help maintain shape and function. Adipose tissue is fat. ...Read more

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Could rheumatoid vasculitis affect breast tissue?

Could rheumatoid vasculitis affect breast tissue?

It is possible!: There are twelve documented cases in the literature. But it requires biopsy confirmation. Breast pain can occur in RA for many reasons, including chest wall inflammation! ...Read more

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What are characteristics of soft tissue sarcomas?

What are characteristics of soft tissue sarcomas?

Wildly variable: "soft tissue sarcomas" encompass over 100 different types of cancers, depending on what tissue it started in (fat, supporting tissue, muscle, bone, guts, etc.); within each tissue type, there are dozens of different cancers. In general, they are lumps under the skin, sometimes with overlying skin color or contour changes. Often neglected because not painful. See a good surgeon, and good luck! ...Read more

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What are some soft tissue sarcoma treatments?

Surgery primary: Primary treatment of sarcoma is surgery, sometimes accompanied by radiation therapy or less often chemotherapy. New treatments being evaluated. ...Read more

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What specialists can diagnose mixed connective tissue disease besides rheumatologists?

What specialists can diagnose mixed connective tissue disease besides rheumatologists?

Any physician: It depends on the expertise. As a rheumatologist we may not necessarily have a corner on the market, but depending on what signs and symptoms the patient has they may be diagnosed by other physicians. It is important to be clear what the true diagnosis is since mctd people can have skin, joint, muscle, lung, heart, kidney involvement to name some. It depends on the stage of the mctd. ...Read more

Tissue (Definition)

The body is composed of tissue that are classically described as beiing derived from three basic embyonic layers known as the endoderm, mesoderm and ectoderm that then differentiate into the structures that compose the body such as skin, soft tissues, bone, muscle, organs, etc. Stem cells are not differentiated and have the potential to ...Read more


Collagen (Definition)

Collagen is a component of extracellular tissue, which is found throughout the body. Collagen is a proten important for tissue strength and tissue healing. There are several differnt subtypes of collagen, depending on where it is found. Collagen has a high content of hydroxyproline, which is ...Read more