Doctor insights on:
Collagen Vascular Diseases Mixed Connective Tissue Disease
Different areas: Collagen vascular diseases or multi-system diseases are just that. They are a group of diseases characterized by autoimmune aberrations. Varied organ systems can be involved - skin, joints or any internal organs - heart, kidneys, blood or nervous system. The way a disease presents itself depends on which areas are involved. See you doctor or rheumatologist. ...Read more
The body is composed of tissue that are classically described as beiing derived from three basic embyonic layers known as the endoderm, mesoderm and ectoderm that then differentiate into the structures that compose the body such as skin, soft tissues, bone, muscle, organs, etc. Stem cells are not differentiated and have the potential to ...Read more
Can be autoimmune: Collagen vascular disease encompasses a series of autoimmune illnesses such as lupus, rheumatoid arthritis, polymyositis and scleroderma to name a few. Each of these can have variations on their diagnostic categories. These were first named becuase there were similar changes in the soft tissues and blood vessels when biopsies were done in people with a collagen vascular diseases. ...Read more
DIFFICULT ANSWER: Collagen vasular diseases include a broad spectrum of illnesses. As a rheumatologist, we do our best to isolate what collagen vasular disease a patient has. The term, collagen vascular disease does not descibe one disease but rather the whole practice of rheumatology. I figure your doctor may have found an abnormal boold test which may or may not be significant. I need more information to help you. ...Read more
What do vertical lines on your nails say about your health??? (I have collagen vascular disease by the way.)
Lines that go from side to side (horizontal) nail are Beau's lines (guess which doctor named them) and certainly can be a reflection of a variety of conditions including collagen vascular disorders (I suspect you were talking about Raynaud's).
Vertical lines however are commonly seen normal healthy people. ...Read more
Why can't you use Bazuka if you have a circulation problem. What effect does it have? I have collagen vascular disease btw and I have verrucas too
Not sure: I cannot find this medicine in my references and not sure how to advise. Can you give more info? ...Read more
Depends: Depends on location of affected organ like lungs, kidneys, intestines. Etc ...Read more
Auto-immune: Auto immune disorder related to salivary glands. Can develop dry mouth, etc. ...Read more
Collagen Vascular: These are diseases that attack the connective tissues of blood vessels. They are typically autoimmune disorders characterized by overactivity of the immune system resulting in auto-antibodies that attack the collagen connective tissue of blood vessels & other tissues, resulting in inlammation & weakness of the connecitve tissues. Examples are lupus, rheumatoid arthritis, scleroderma, & sjogren's. ...Read more
Sick Support: You can think of collagen as sort of the glue and supporting tissue that holds our bodies together. There is collagen holding our eye lens in place and collagen in our ligaments of our joints and other places. Collagen vascular disease is typically an autoimmune disease which affects all sorts of tissues. Rheumatologists are the specialists who typically see this illness. ...Read more
Can you get cured from Collagen Vascular Disease? I'm taking nifedipine. Will I have to take them for the rest of my life. I'm 16!
Why can't you use Bazuka gel to treat verrucas if you have a circulation problem. What effect does it have? I have collagen vascular disease btw.
Strong Acid: Bazuka gel is a strong salicyclic acid formulary that will cause damage to the layers of the skin of the wart & to the layers surrounding the wart. With collagen vascular disease it will take a long time to heal those layers back and the chance of infection would be high. Natural castor oil is effective in sloughing off wart tissue when placed directly on the wart and sealed with a bandage daily! ...Read more
I take nifedipine 5mg for collagen vascular disease. Colour of toes is fine when I take them but my toes go INSANELY COLD!! Why?? What's happening???
Is collagen vascular disease curable or do I have to live with it for the rest of my life. I'm 16!!! I take nifedipine btw?
No cure, but: There's no cure for collagen vascular disease but the course is highly variable and it burns out in some. For the rest, there are increasingly effective treatments so stay the course and remain optimistic. (there are many diseases today that are curable that were incurable in the past). ...Read more
Is hughes disease a vascular disease or connective tissue disease? I forgot to ask rheumatologist when recently diagnosed.
All: Hughes disease or antiphaspholipid synrome, has sticky blood causes clotting in unwanted places and time, due to thrombosis depending on the site causes variety of symptoms, TIA pe, deep vein thrombosis miscarriage etc could be immunological, as antiphaspho lipid antibodies are found, some times lupus also found in hughes syn. Warfarin is used ...Read more
Can middle chest pain when pressed be due to anything pertaining vascular disorder due to connective tissue disease?
Typically does not.: Bladder control problems are common. Mctd, which primarily affects females is uncommon. Bladder issues are not specifically related to mctd. ...Read more
I have Mixed Connective Tissue Disease. Are new Beau's Lines on my nails an indication of active disease?
I was told that I either have sle or mixed connective tissue disease (i already have a rheumatology appt) I was just wondering what's the difference?
Overlap of signs: Sle (lupus) and mixed connective disease have overlap of some symptoms and signs. When there aren't enough diagnostic criteria to conclude lupus, but some characteristic findings of connective tissue disease, they call it mixed. Lupus has 11 possible categories of labs or physical findings according to the acr. ...Read more
Mixed connective tissue disease a much milder disease than the cousins it may share features with: sly, sjogren's, scleroderma.
It is characterized by find the "rnp" antibody, in the absence of the sm-antibody. Usually treated with plaquenyl. May have milder sjogren's, raynauds than other diseases, may cause joint pain, but no damage. We treat the sx that dominate and vary between pts with mctd. ...Read more
Any physician: It depends on the expertise. As a rheumatologist we may not necessarily have a corner on the market, but depending on what signs and symptoms the patient has they may be diagnosed by other physicians. It is important to be clear what the true diagnosis is since mctd people can have skin, joint, muscle, lung, heart, kidney involvement to name some. It depends on the stage of the mctd. ...Read more
Immunity versus pain: Mixed connective tissue disease results from the immune system attacking the body itself. Muscle pain is common and is due to inflammation. Fibromyalgia is a syndrome of symptoms including fatigue, non-restful sleep, and widespread pain. It may be due to imbalance in chemicals in the nerves in the brain. Muscle pain is universal but the immune system is not involved in fibromyalgia. ...Read more
Can a person have mixed connective tissue disease with a positive ANA and low positive rnp levels?
Hight titers of anti rnp antibodies are the trade mark of mctd however it is possible to be in early phase of transformation from a lupus background were other anas are still dominant.
The clinical picture would take precedent with overlapping signs such as raynaulds, myositis and other signs of scleroderma.
None of these tests are diagnsotic in the absence of clinical illness. ...Read more
Can mixed connective tissue disease be diagnosed with a positive ANA and positive rnp anitibodies?
No: It's neither. It's an overgrowth of fibrous tissue that's poorly understood. Sometimes an injection can break it, or surgery's an option. Best wishes. ...Read more
Collagen is a component of extracellular tissue, which is found throughout the body. Collagen is a proten important for tissue strength and tissue healing. There are several differnt subtypes of collagen, depending on where it is found. Collagen has a high content of hydroxyproline, which is ...Read more
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