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Doctor insights on: Collagen Vascular Diseases Mixed Connective Tissue Disease

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Where do collagen vascular diseases show up?

Where do collagen vascular diseases show up?

Different areas: Collagen vascular diseases or multi-system diseases are just that. They are a group of diseases characterized by autoimmune aberrations. Varied organ systems can be involved - skin, joints or any internal organs - heart, kidneys, blood or nervous system. The way a disease presents itself depends on which areas are involved. See you doctor or rheumatologist. ...Read more

Tissue (Definition)

The body is composed of tissue that are classically described as beiing derived from three basic embyonic layers known as the endoderm, mesoderm and ectoderm that then differentiate into the structures that compose the body such as skin, soft tissues, bone, muscle, organs, etc. Stem cells are not differentiated and have the potential to ...Read more


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What's the significance of collagen vascular diseases?

Can be autoimmune: Collagen vascular disease encompasses a series of autoimmune illnesses such as lupus, rheumatoid arthritis, polymyositis and scleroderma to name a few. Each of these can have variations on their diagnostic categories. These were first named becuase there were similar changes in the soft tissues and blood vessels when biopsies were done in people with a collagen vascular diseases. ...Read more

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What are the concerns with having collagen vascular diseases?

DIFFICULT ANSWER: Collagen vasular diseases include a broad spectrum of illnesses. As a rheumatologist, we do our best to isolate what collagen vasular disease a patient has. The term, collagen vascular disease does not descibe one disease but rather the whole practice of rheumatology. I figure your doctor may have found an abnormal boold test which may or may not be significant. I need more information to help you. ...Read more

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How does collagen vascular disease affect the bladder?

How does collagen vascular disease affect the bladder?

Few do, but: Scleroderma (pss) can turn the autonomically controlled bladder muscle wall to contract from collagen based scarring with contracture, but few other would do so! ...Read more

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Is lupus the same thing as collagen vascular disease. If not what's the difference?

Is lupus the same thing as collagen vascular disease. If not what's the difference?

Yes: Lupus is a collagen vascular disease. Like a cold is an upper respiratory infection. Cvd is a general term that includes many diseases including lupus. ...Read more

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What do vertical lines on your nails say about your health??? (I have collagen vascular disease by the way.)

Don't worry....: Lines that go from side to side (horizontal) nail are Beau's lines (guess which doctor named them) and certainly can be a reflection of a variety of conditions including collagen vascular disorders (I suspect you were talking about Raynaud's).

Vertical lines however are commonly seen normal healthy people. ...Read more

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What complications does collagen vascular disease cause?

What complications does collagen vascular disease cause?

Depends: Depends on location of affected organ like lungs, kidneys, intestines. Etc ...Read more

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Is sjogrens considered a collagen vascular disease?

Is sjogrens considered a collagen vascular disease?

Auto-immune: Auto immune disorder related to salivary glands. Can develop dry mouth, etc. ...Read more

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What's collagen vascular disease?

What's collagen vascular disease?

Collagen Vascular: These are diseases that attack the connective tissues of blood vessels. They are typically autoimmune disorders characterized by overactivity of the immune system resulting in auto-antibodies that attack the collagen connective tissue of blood vessels & other tissues, resulting in inlammation & weakness of the connecitve tissues. Examples are lupus, rheumatoid arthritis, scleroderma, & sjogren's. ...Read more

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Can you die from collagen vascular disease?

Collagen disease: Simple answer: yes. If there is significant vascular, cardiac, pulmonary, or renal involvement, yes. ...Read more

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What sort of disease is a collagen vascular disease?

Sick Support: You can think of collagen as sort of the glue and supporting tissue that holds our bodies together. There is collagen holding our eye lens in place and collagen in our ligaments of our joints and other places. Collagen vascular disease is typically an autoimmune disease which affects all sorts of tissues. Rheumatologists are the specialists who typically see this illness. ...Read more

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What is the definition or description of: Collagen vascular disease?

Misleading.: Collagen vascular disease was a term originally used to describe an abnormality of the collagen protein associated with blood vessels. It is now used to describe a collagen protein disorder in many types of connective tissues, not just blood vessels. ...Read more

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Can you get cured from Collagen Vascular Disease? I'm taking nifedipine. Will I have to take them for the rest of my life. I'm 16!

Can you get cured from Collagen Vascular Disease? I'm taking nifedipine. Will I have to take them for the rest of my life. I'm 16!

Come and Go: You may or may not need Nifedipine long term. That drug doesn't 'cure' the CVDz. .. it is used to prevent spasm of blood vessels. .. you can go off and on the drug periodically to see how you respond. .. preferably with a doctors guidance ...Read more

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Why can't you use Bazuka gel to treat verrucas if you have a circulation problem. What effect does it have? I have collagen vascular disease btw.

Strong Acid: Bazuka gel is a strong salicyclic acid formulary that will cause damage to the layers of the skin of the wart & to the layers surrounding the wart. With collagen vascular disease it will take a long time to heal those layers back and the chance of infection would be high. Natural castor oil is effective in sloughing off wart tissue when placed directly on the wart and sealed with a bandage daily! ...Read more

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I take nifedipine 5mg for collagen vascular disease. Colour of toes is fine when I take them but my toes go INSANELY COLD!! Why?? What's happening???

I take nifedipine 5mg for collagen vascular disease. Colour of toes is fine when I take them but my toes go INSANELY COLD!! Why?? What's happening???

Too low a dose: The dose of Nifedipine is much too low to have any real benefit for your Raynauds. I start my patients at an extended realease dose of 30 mg daily and increase if needed. ...Read more

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Is collagen vascular disease curable or do I have to live with it for the rest of my life. I'm 16!!! I take nifedipine btw?

No cure, but: There's no cure for collagen vascular disease but the course is highly variable and it burns out in some. For the rest, there are increasingly effective treatments so stay the course and remain optimistic. (there are many diseases today that are curable that were incurable in the past). ...Read more

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Is hughes disease a vascular disease or connective tissue disease? I forgot to ask rheumatologist when recently diagnosed.

Is hughes disease a vascular disease or connective tissue disease? I forgot to ask rheumatologist when recently diagnosed.

All: Hughes disease or antiphaspholipid synrome, has sticky blood causes clotting in unwanted places and time, due to thrombosis depending on the site causes variety of symptoms, TIA pe, deep vein thrombosis miscarriage etc could be immunological, as antiphaspho lipid antibodies are found, some times lupus also found in hughes syn. Warfarin is used ...Read more

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Can middle chest pain when pressed be due to anything pertaining vascular disorder due to connective tissue disease?

Can middle chest pain when pressed be due to anything pertaining vascular disorder due to connective tissue disease?

See a doctor: Pain in the rib cage can be due to costochondritis. This is an inflammation of the cartilage where the rib meets the sternum. If you press the spot does it hurt? If so it could be costochondritis. See your doctor. ...Read more

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What's the difference between mixed connective tissue disease and fibromyalgia? I'm confused.

What's the difference between mixed connective tissue disease and fibromyalgia? I'm confused.

Unrelated: These two issues are unrelated. Mctd is an autoimmune disease. Fibromyalgia is a disorder of chronic widespread pain manifesting as tender points and fatigue. ...Read more

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How do mixed connective tissue disease affect bladder control?

How do mixed connective tissue disease affect bladder control?

Typically does not.: Bladder control problems are common. Mctd, which primarily affects females is uncommon. Bladder issues are not specifically related to mctd. ...Read more

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I have Mixed Connective Tissue Disease. Are new Beau's Lines on my nails an indication of active disease?

I have Mixed Connective Tissue Disease. Are new Beau's Lines on my nails an indication of active disease?

Their is no. .: Relationship between MCTD and the Beau's Lines in my years of practice. They can look like ridging from psoriasis, and this must be distinguished. Any significant illness can cause them, but MCTD rarely, rarely would be so severe! PS: You are on no meds for MCTD! ...Read more

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I was told that I either have sle or mixed connective tissue disease (i already have a rheumatology appt) I was just wondering what's the difference?

I was told that I either have sle or mixed connective tissue disease (i already have a rheumatology appt) I was just wondering what's the difference?

Overlap of signs: Sle (lupus) and mixed connective disease have overlap of some symptoms and signs. When there aren't enough diagnostic criteria to conclude lupus, but some characteristic findings of connective tissue disease, they call it mixed. Lupus has 11 possible categories of labs or physical findings according to the acr. ...Read more

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I know someone with mixed connective tissue disease....Is it a serious illness?

I know someone with mixed connective tissue disease....Is it a serious illness?

Mixed CT disease: Mixed connective tissue disease (mctd) is often relatively mild but can be associated with potentially serious internal complications involving the heart, esophagus and lungs. ...Read more

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Possible mixed connective tissue disease, doctor says? What is a mixed disease?

Possible mixed connective tissue disease, doctor says? What is a mixed disease?

MCTD!: Mixed connective tissue disease a much milder disease than the cousins it may share features with: sly, sjogren's, scleroderma.
It is characterized by find the "rnp" antibody, in the absence of the sm-antibody. Usually treated with plaquenyl. May have milder sjogren's, raynauds than other diseases, may cause joint pain, but no damage. We treat the sx that dominate and vary between pts with mctd. ...Read more

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What specialists can diagnose mixed connective tissue disease besides rheumatologists?

What specialists can diagnose mixed connective tissue disease besides rheumatologists?

Any physician: It depends on the expertise. As a rheumatologist we may not necessarily have a corner on the market, but depending on what signs and symptoms the patient has they may be diagnosed by other physicians. It is important to be clear what the true diagnosis is since mctd people can have skin, joint, muscle, lung, heart, kidney involvement to name some. It depends on the stage of the mctd. ...Read more

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What are the differences between myofascial pain syndrome and mixed connective tissue disease?

What are the differences between myofascial pain syndrome and mixed connective tissue disease?

Immunity versus pain: Mixed connective tissue disease results from the immune system attacking the body itself. Muscle pain is common and is due to inflammation. Fibromyalgia is a syndrome of symptoms including fatigue, non-restful sleep, and widespread pain. It may be due to imbalance in chemicals in the nerves in the brain. Muscle pain is universal but the immune system is not involved in fibromyalgia. ...Read more

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Can a person have mixed connective tissue disease with a positive ANA and low positive rnp levels?

Can a person have mixed connective tissue disease with a positive ANA and low positive rnp levels?

Inprobable: Hight titers of anti rnp antibodies are the trade mark of mctd however it is possible to be in early phase of transformation from a lupus background were other anas are still dominant.
The clinical picture would take precedent with overlapping signs such as raynaulds, myositis and other signs of scleroderma.
None of these tests are diagnsotic in the absence of clinical illness. ...Read more

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Can mixed connective tissue disease be diagnosed with a positive ANA and positive rnp anitibodies?

NO.: You must have a compatible clinical picture first and the absence of another diffuse connective tissue disorder which could explain the symptoms and lab findings. A high titer ANA and anti-u1-rnp is a pretty good marker of mctd though. ...Read more

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Is Palmar fibrosis a autoimmune disease or Mixed connective tissue disease?

Is Palmar fibrosis a autoimmune disease or Mixed connective tissue disease?

No: It's neither. It's an overgrowth of fibrous tissue that's poorly understood. Sometimes an injection can break it, or surgery's an option. Best wishes. ...Read more

Collagen (Definition)

Collagen is a component of extracellular tissue, which is found throughout the body. Collagen is a proten important for tissue strength and tissue healing. There are several differnt subtypes of collagen, depending on where it is found. Collagen has a high content of hydroxyproline, which is ...Read more


Dr. Christopher Bibb
53 Doctors shared insights

Collagen Vascular Disease (Definition)

Collagen vascular disease was a term originally used to describe an abnormality of the collagen protein associated with blood vessels. It is now used to describe a collagen protein disorder in many types of connective tissues, ...Read more