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Doctor insights on: Collagen Vascular Diseases Marfan Syndrome

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Where do collagen vascular diseases show up?

Where do collagen vascular diseases show up?

Different areas: Collagen vascular diseases or multi-system diseases are just that. They are a group of diseases characterized by autoimmune aberrations. Varied organ systems can be involved - skin, joints or any internal organs - heart, kidneys, blood or nervous system. The way a disease presents itself depends on which areas are involved. See you doctor or rheumatologist. ...Read more

Dr. Scott McLean
327 doctors shared insights

Marfan Syndrome (Definition)

Marfan's syndrome is a genetic disorder caused by defects in a protein called fibrillin that, along with collagen, provides most of the structural support of our tissues. Individuals with Marfan's are often tall, lanky, have long arm spans, and are hyperflexible. The most serious complication of Marfan's is caused by defects in the wall of the aorta, the large blood vessel that leaves the heart and supplies the ...Read more


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What's the significance of collagen vascular diseases?

Can be autoimmune: Collagen vascular disease encompasses a series of autoimmune illnesses such as lupus, rheumatoid arthritis, polymyositis and scleroderma to name a few. Each of these can have variations on their diagnostic categories. These were first named becuase there were similar changes in the soft tissues and blood vessels when biopsies were done in people with a collagen vascular diseases. ...Read more

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What are the concerns with having collagen vascular diseases?

DIFFICULT ANSWER: Collagen vasular diseases include a broad spectrum of illnesses. As a rheumatologist, we do our best to isolate what collagen vasular disease a patient has. The term, collagen vascular disease does not descibe one disease but rather the whole practice of rheumatology. I figure your doctor may have found an abnormal boold test which may or may not be significant. I need more information to help you. ...Read more

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How effective is vascular grafting for treating Marfan syndrome?

How effective is vascular grafting for treating Marfan syndrome?

Vascular grafting: should one get an aneurysm related to Marfan, grafting can be very effective, otherwise grafting is rather superfluoius to the diagnosis ...Read more

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Could preimplantation genetic diagnosis or genetic engineering get rid of diseases like Marfan syndrome?

Could preimplantation genetic diagnosis or genetic engineering get rid of diseases like Marfan syndrome?

Yes: An embryo could be tested for the marfan mutation and only implanted if it did not contain that mutation. The same is true for a large number of other autosomal dominant or recessive diseases. ...Read more

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Can you tell me the features of the disorder Marfan syndrome?

Marfan's syndrome: It is a broad topic. Difficult to cover here. Please refer to the site: http://en.Wikipedia.Org/wiki/marfan_syndrome. ...Read more

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I need help finding a dr. In Michigan experienced in Marfan Syndrome to confirm or rule out this disease. Thank you.

Genetics: You are probably best served finding an expert in genetics. Check with your closest major hospital or medical university for a list of references. ...Read more

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Does someone with celiac disease have a higher risk of also having Marfan syndrome?

No association: Don't believe that there is any association between the two. ...Read more

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Is it possible for someone to have a combo of connective tissue disorders such as Marfan syndrome and ehlers danlos syndrome?

Is it possible for someone to have a combo of connective tissue disorders such as Marfan syndrome and ehlers danlos syndrome?

Yes, but unlikely: Both Marfan syndrome (see http://www.nhlbi.nih.gov/health/health-topics/topics/mar/) and Ehlers Danlos syndrome (see http://www.nlm.nih.gov/medlineplus/ency/article/001468.htm) are conditions where mutations in proteins that are main components of connective tissue are abnormal which can result in a number of tissue abnormalities and possible health problems.Not likely both conditions at same time ...Read more

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Is Marfan syndrome a sex-linked disease?

No: Marfan syndrome is an autosomal dominant connective tissue disorder caused by abnormal microfibrillin protein. If a parent is affected by the disorder, their offspring has a 50/50 chance of inheriting it, regardless of whether the baby is a boy or a girl. ...Read more

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Dr. Christopher Bibb
42 doctors shared insights

Collagen Vascular Disease (Definition)

Collagen vascular diseases are a variety of conditions that involve disorders of collagen. Collagen is a tough, glue-like protein that makes up 30% of body protein. It shapes the structure of tendons, bones, and connective tissues. Problems with the immune system can affect these structures, and lead to conditions such as Rheumatoid Arthritis, Scleroderma, and ...Read more


Collagen (Definition)

Collagen is a component of extracellular tissue, which is found throughout the body. Collagen is a proten important for tissue strength and tissue healing. There are several differnt subtypes of collagen, depending on where it is found. Collagen has a high content of hydroxyproline, which is ...Read more