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Doctor insights on: Colchicine Vs Allopurinol

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Dr. Tony Willson
256 doctors shared insights

Colchicine (Definition)

Colchicine is used to treat several inflammatory conditions. It is known best as a treatment for acute gout and prophylaxis for gout attacks. It is also used to treat less common conditions such as familial mediterranean fever, skin ...Read more


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I have been taking allopurinol for 1 week. I now have a gout attack. Can I take colchicine as well? I

Wrong order!: Taking Allopurinol during an attack will worsen and prolong it. My regimen is this: establish diagnosis. You can start a nsaid, inject the affected joint(s) with steroids, start colchicine, bid is adequate with the other meds. After three days start Allopurinol 100mg x 1wk, 200mg x 1wk, and then the full dose. The cochicine can be cut back to once daily. ...Read more

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I started allopurinol 2 weeks ago and now have a gout attack should I stop and take colchicine or take both together?

I started allopurinol 2 weeks ago and now have a gout attack should I stop and take colchicine or take both together?

You can: Try both together but if not helping in 24-48 hours stop Allopurinol .take Colchicine alone for 5-7 days then restart Allopurinol ......hope this is helpful!


Dr Z ...Read more

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I've had a gout attack yesterday after 5 years & took Allopurinol 2 X 100mg yesterday & 1 X 100 mg today. No relief. Can I take Colchicine also?

I've had a gout attack yesterday after 5 years & took Allopurinol 2 X 100mg yesterday & 1 X 100 mg today. No relief. Can I take Colchicine also?

Wrong move: Allopurinol will prolong the attack. Stop it immediately. It is only used on a daily basis to prevent future attacks. Colchicine is not very effective unless it is started very early in the attack. Use an NSAID such as naproxen or indomethacin. ...Read more

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I'm taking allopurinol together with colchicine.if no more flare, can I drop colchicine but continously take allopurinol?will gout attack reoccur?

Yes; possibly: You can stop Colchicine and use Allopurinol alone to prevent recurrent attacks. Keeping your Uric Acid level below 6 with Allopurinol and a low purine diet can reduce your likelihood of attacks in the future. ...Read more

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I take colchicine with allopurinol for 3 months. If no gout attack I'll reduce the colchicine but continously take allopurinol. Do this regime is ok?

I take colchicine with allopurinol for 3 months. If no gout attack I'll reduce the colchicine but continously take allopurinol. Do this regime is ok?

Gout rx: Perfect plan. Adjust diet. Take in tart cherry juice and tart cherries, 20/day. Add Lemon extract 4 tblspns / day. And avoid alcohol, animal fats, organ meats, anchovies, sardines, tuna, salmon, and shellfish. Limit other meats to 4 oz per day. Avoid high fructose corn syrup containing drinks and foods. Add egg whites, quinoa, soy as protein. Eat lots of citrus fruit and veggies. Drink 3 liters /d ...Read more

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For gout attack could I take : diclofenac 50mg, colchicine & allopurinol 100mg, all together?

Allopurinol Chronic: For acute gout Colchicine and diclofenac are reasonable. Do not exceed the recommended dose of Colchicine and stop immediately if diarrhea occurs.
Allopurinol is to prevent chronic gout. Many patients starting Allopurinol will have an acute gout attack because attacks occur when uric acid levels go up or down. To prevent this some patients take Colchicine daily for up to 6 months. ...Read more

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I have been put on a long term treatment for elevated uric acid with 1 tablet Colchicine and 100mg Allopurinol daily. Is the Colchicine necessary?

Usually not: Colchicine is usually reserved for an acute gout attack, not for preventative measures. Allopurinol should be stopped during an acute gout attack, and restarted once the pain has ressolved. Go see your doctor if you have questions about the meds he/she prescribed you. ...Read more

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Can I take colchicine alone as a preventative for gout? Will it lower uric acid levels or must I take with either Allopurinol or Uloric?

Colchicine: Colchicine alone is effective in diminishing gout. Yes. Allopurinol is not mandatory but of course helps. Also, avoid alcohol, animal fats, organ meats and shellfish. Limit other meats to 4 oz per day. Avoid high fructose corn syrup containing drinks. Add egg whites, quinoa, soy as protein. Eat lots of fruit and veggies. Drink 3 liters per day. ...Read more

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I'm taking allopurinol and colchicine every day.no sign for gout attack until today.can I take red meat (beef) as much and as often as I like?

Meat and gout: No you should not. Limit red meat to 4-6 oz 3 times per week. Incline diet toward more and more fruit and veggie -- less meat. ...Read more

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Besides colchicine and allopurinal, what medication is there to take for gout?

Besides colchicine and allopurinal, what medication is there to take for gout?

Several.: Probenecid. Probenecid/colchicine comination. Uloric. Finally, nsaids for an acute attack! ...Read more

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Which is more affective pain management of a gouty foot flare-up, Naproxen or Celebrex (celecoxib)? (along with Colchicine) Allipurinol already prescribed.

Which is more affective pain management of a gouty foot flare-up, Naproxen or Celebrex (celecoxib)? (along with Colchicine) Allipurinol already prescribed.

Probably naproxen: Naproxen has been used for many years to treat acute episodes of gout-colcichine has been used longer but has more side effects if pushed. Celebrex (celecoxib) is an N SAID too but used more for having less gastrointestinal side effects. So the person who knows best with your history is the prescribing. Doctor. ...Read more

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I have a gouty athritis and my ALT is80, I take 50mg of diclofenac 3x aday, colchicne 3aday and 300mg alluprnol 3x aday, was my ALT is normal,?

I have a gouty athritis and my ALT is80, I take 50mg of diclofenac 3x aday, colchicne 3aday and 300mg alluprnol 3x aday, was my ALT is normal,?

Slightly high...: Your alanine transaminase (alt) was slightly high at 80. It should be less than 60. It is a sensitive but not a specific test of liver function. Talk to your doctor about what you ought to do and what might be causing the elevation. Also, talk to him about a low purine diet which may help you avoid having to take medications with potentially adverse liver effects. Colchicine also ought to be prn... ...Read more

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Please describe the medication: colchicine?

Please describe the medication: colchicine?

Gout rx: Colchicine is used to treat several inflammatory conditions. It is known best as a treatment for acute gout and prophylaxis for gout attacks. It is also used to treat less common conditions such as familial mediterranean fever, skin vasculitis, and chronic pericarditis. ...Read more

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Is colchicine recommended for treating gout?

Is colchicine recommended for treating gout?

Yes......: However, there are other medicines that may be better. Treatment of an acute gouty flare is different that for prevention of these. See your primary care doctor to see what medicine or combinations of medicine is best for you. ...Read more

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What are the effects of colchicine treatment?

See below: Most common are diarrhea, nausea, vomiting and stomach pain. Long list of rare. Get immediate attention if gastrointestinal bleeding, severe diarrhea, muscle weakness or difficult breathing all which are rare. ...Read more

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Is allopurinol nephro toxic?

Is allopurinol nephro toxic?

Yes, rarely: There are two different 'kidney' concerns with allopurinol. There are some people who have an allergic reaction to this medication at the kidney level but not necessarily any other symptoms... This is called interstitial nephritis. It is also a medication that is cleaned out of the body by the kidneys and therefore as the kidney function becomes less, the dosing needs to be decreased. ...Read more

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Why does allopurinol treat gout?

See below: It lowers the uric acid production in the blood, thereby preventing hyperurecemia and gouty attacks. ...Read more

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Side effects from taking allopurinol?

Allopurinol: Most common is skin rash. May precipitate a gout attack during initiation of therapy. ...Read more

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Is pregnancy safe while on colchicine?

Not perfectly safe: Colchicine is a class c medication in pregnancy, meaning there are not human trials and that animal trials were either not done or showed harm. Risks and benefits of taking medications during pregnancy must be weighed in regard to the consequences of not taking the medications as both have risks. Discuss with your prescribing doctor and ob. ...Read more

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How effective is allopurinol to avoid gout?

How effective is allopurinol to avoid gout?

Very!: Allopurinol has been around for some time is really quite safe. Rare side-effects do occur, but I have not seen them. When Allopurinol is started (or uloric) start at a low dose and work up. Lowering uric acid in the blood to0 quickly will precipate a gout attack, which is a major reason for using pre-dose Colchicine and/or an anti-inflammatory drug. Used properly, gouty arthritis need not be! ...Read more

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What are some adverse reactions to colchicine?

What are some adverse reactions to colchicine?

Nausea and vomiting: Nausea, vomiting, and stomach irritation are some side effects for a short term dosage. Long term dosing may have the added side effect of liver damage. Your doctor will monitor you when on this med. ...Read more

Dr. Gregory Moneta
112 doctors shared insights

Zyloprim (Definition)

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Dr. Thomas Fiala
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Purinol (Definition)

Purinol is a gout agent which is a kind of hormonal, ...Read more