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Doctor insights on: Codeine Vs Hydrocodone

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Hydrocodone (Definition)

Hydrocodone or dihydrocodeinone is a semi-synthetic opioid derived from two naturally occurring opiates: Codeine or thebaine. It is an orally active narcotic analgesic and antitussive. It is available in tablet, capsule, and syrup form. It is used to treat moderate to severe pain or as an antitussive to treat cough. Hydrocodone affects pain by ...Read more


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Hydrocodone or codeine. Which is more addicting?

Both are : Addicting and should only be used short term to treat pain unless advised otherwise by a physician. ...Read more

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What is the difference: hydrocodone vs. Codeine?

One semi-synthetic: Codeine is a naturally occurring chemical found in opium, along with morphine and papaverine. The problem is that Codeine is poorly absorbed (like morphine) and higher doses are needed for it to work, in addition it has histamine effects like sneezing, itching and GI distress. Hydrocodone adds a molecule to codeine, where it is better absorbed and more potent, with fewer histamine side effects. ...Read more

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Is there a difference between hydrocodone an codeine?

Is there a difference between hydrocodone an codeine?

Yes : They are different meds. Both meds are considered opioids and work on the mu receptor in different ways. Codeine gets broken down to morphine in your body to work and hydrocodone does not need to be broken down to work but it has metabolites (broken down products) that cause pain relief as well. ...Read more

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How does the strength of codeine compare to hydrocodone?

How does the strength of codeine compare to hydrocodone?

There are many rules: and they are all inaccurate, because the individual differences in how these drugs are metabolized are so great that odds are good any table is going to be wrong. However, in general, codeine is the least potent of all the opioids, with 60 mg being the equivalent of 5 mg of oxycodone and probably 7.5 mg of hydrocodone ON AVERAGE. This is if taken by mouth. IM codeine is more potent - about twice. ...Read more

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Please advise what is the difference between codeine and hydrocodone?

Chemical structure: They are both opioids (related to morphine), hydrocodone is a semi- synthetic opioid derived from Codeine and a bit stronger. ...Read more