Doctor insights on:
Nobody truly knows: what the toxic substances are and how they work, and also why some people use the exact same drug in the exact same amount and don't have adverse effects, while other people will have seizures on even lower doses. Stimulants put the brain in overdrive, and a particular part of the chemical of some stimulants (the methoxy- radical) seems to cause more damage. This is what is in bath salts and meth. ...Read more
Do selective adeno-adenergic blockers (prazosin, terazosin, doxazosin, trimazosin) protect from acute cocaine-induced vasoconstrictive damage?
Some: Cocaine causes it's effect by preventing the reuptake of monamine (epinephrine, etc) and causes these neurotransmitters to continue exciting the a1 receptor. The meds listed block alpha-1 receptors, so theoretically will blunt the effects of Cocaine on some vessels, but focus mostly (esp. Tamsulosin) on a specific sub-type (alpha-1a) that is mostly in the bladder, not in the vessels. ...Read moreSee 1 more doctor answer
Any advice? I have never done cocaine and i never will. I'm just asking in general; doesn't it do permanent mind damage or something?
Nice that you can: Predict the future for yourself. Most people really don't know what they will or won't do, particularly since we don't know what curves life will throw us. Cocaine can cause permanent damage, but that takes a lot of Cocaine over a long period of time. There is no evidence, for the vast majority, that occasional Cocaine use causes "mind" damage, but depression, paranoia and psychosis if high dose. ...Read more
Many harmful effects: Besides being highly addictive, Cocaine can do harm in many ways. It is a powerful vasoconstrictor, & can cause a shortage of bloodflow & permanent damage to any organ/body part. Anxiety, agitation, paranoia, tremors, inability to sleep and mania or grandiosity are most common effects. Heart attack and stroke are deadliest. Fetuses, infants, children and teens can get brain damage w/ or w/o stroke. ...Read more
If someone regularly used cocaine by snorting it for 5 years but stopped 15 years ago; is there any lingering heart risks? Is damage permanent?
Probably not: Depends on some details of those 5 yrs. Generally cocaine is not known for long term or delayed health risks although the effects of crack use in young people is pretty scary from a mental health perspective. If there was never a dose large enough to cause a heart attack then lingering heart problem is not likely. However, the risk of a sudden fatal arrhythmia with continued use increases with age ...Read moreSee 1 more doctor answer
My friend did cocaine on two separate occasions two years ago and was wondering if she had could have caused permanent damage to her nose?
Damage Is Possible: Cocaine users often snort powdered Cocaine up their nostrils so that the drug can be quickly absorbed by fine capillaries which line the nasal passages. Cocaine is toxic to the tissue, but it also acts as an anesthetic agent so the user does not feel the tissue damage. Chronic use can destroy the mucosa as well as erode the nasal septum. The mucosa can regenerate but not the nasal cartilage. ...Read more
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