Doctor insights on:
Cns Lupus Message
It can but: There is lack of sensitivity of conventional MRI is there no doubt and there is indication to use mrs(magnetic resonance spectroscopy) we can measure brain metabolites.Mrs tests will show consistently reduction in n-acetyle asparate which is a specific nural marker for CNS lupus MRI still remains gold standard for assessment which is non invasive but there are problems with sensitivity/specificity. ...Read moreSee 1 more doctor answer
I have autonomicneuropathy from lupus, i get vertigo/headach too i was told those who have CNS involvement have a poor prognosis & die early , true?
Looking for top doctors in the u.S. Who treat CNS lupus/ceribritis vasculitis. My 22 year old niece has it and none of her drs have ever treated it.?
Need Rheumatologist: My suggestion is to see a progressive rheumatologist in your relatively local area. There are many great centers around the country. Your location and access to the doctor can not be discounted. This is a long term disease, not a single visit issue. Many great doctors are around you. ...Read moreSee 1 more doctor answer
If you have CNS lupus does that mean you have a poorer prognosis than the average lupus patient & is vertigo and headaches symptom of CNS lupus?
Yes to symptoms: There are very many symptoms of CNS lupus and vertigo and headaches are common features. V cns disease and kidney disease are two of the more serious system involvements in lupus depending on all of the CNS symptoms will determine long term survival. ...Read moreSee 1 more doctor answer
I have autonomic dysfunction with lupus since that is considered CNS related; can I still live a normal life span? Drs say CNS = b a d lupus prognosis
Yes: A "normal lifespan" is pretty subjective. It could be 60's, 70's. In uganda most men don't live beyond their late 40's. Stay positive. Think quality over quantity. No one is guaranteed a particular lifespan. That being said with current treatments for sle regardless of which area is effected (brain/cns, GI tract, skin, etc.) you can still live a good long while. ...Read moreSee 1 more doctor answer
Just found out I have a nonspecific abnormal lesion on my right side of brain. I have lupus. Could this be CNS lupus. Have numbness slurred speech?
See details: It is very difficult to determine if a single lesion is related specifically to lupus, to antiphospholipid antibodies, emboli or totally unrelated to all of these. You need to ask your doctors who have the detailed information needed to give you a precise answer. ...Read moreSee 1 more doctor answer
What are the stages of Lupus? I have SLE and CNS. A lot of fluid retention lately and swelling. Actually the only thing good is my labs are all normal
Severity: Lupus has varying severity and manifestations. It can be active or inactive. We don't usually use the term "stages." What comes into question is the diagnosis of CNS lupus if your labs are truly normal. ANA lupus is rare given modern testing methods and with more severe lupus such as CNS lupus, one would expect positive dsDNA Ab and/or low C3, C4. Ask your doctor if that is your definite diagnosis ...Read moreSee 1 more doctor answer
Can CNS lupus diagnosis easily be missed in a person with lupus diagnosis with frequent episodes of confusion, mental fog, giddiness, black outs but normal mri?
Could be difficult: Several possibilities, you might be having reactions to your medications, you could be experiencing seizures and/or migraines, and could indeed have other co-morbidities. Might urge you have this further evaluated. Sometimes, MRI will miss very small lesions, and spinal fluid might be productive. ...Read more
Is it possible that a person have lupus and CNS symptoms along with fatigue, pos ANA and double stranded dna? And not the classic symptoms?
I have postural orthostatic tachycardia syndrome from lupus. I only take plaquenil (hydroxychloroquine) since lupus gave me pots is that a poorer prognosis since its the nervous system (i heard if it affects CNS its bad)?
YES and many more : Few listed: cardiomyopathy (rare, relationship to Hydroxychloroquine unclear) central nervous system: ataxia, dizziness, emotional changes, headache, irritability, lassitude, nervousness, nightmares, psychosis, seizure, vertigo dermatologic: alopecia, angioedema, bleaching of hair, pigmentation changes (skin and mucosal; black-blue color), rash (acute generalized exanthematous pustulosis, etc. ...Read moreSee 1 more doctor answer
On 40mg of Prednisone, Cellcept (mycophenolate mofetil) 1000mg for abt 3wks for CNS lupus. Before meds - norm WBC of 6ish. New CBC + Diff WBC 12.75, abs neut11.60. Concern?
Probably not: The increases in WBC and neut are expected when on high doses of prednisone. However you need to have follow up with your rheumatologist to address this issue since only a direct exam can help detect the presence of an infection which may be masked by the medications you are taking. ...Read more
Md thinks my lupus-like disease is affecting my cns.Prednisone stopped dizziness, nighttime sob &palpitation. Since taper, awaken sob, heart racing.Why?
More info: Do the palpitations awaken you or do you awaken with a startle which causes the heart to race? How fast is your pulse when you note the palpitations? How long do they last? Do you also get palpitations on other occasions. A pulse rate of 120 to 150 has more significance than one of 90, for example. A startle reaction may last a minute or 2 as opposed to significant tachycardia. Heart monitor helps. ...Read more
It is where lupus: It is where lupus attacks your cental nervous system which is made up of your brain and spinal cord. This can take the form of vasculitis, stroke, seizures, transverse myelitis, and neurocognitive dysfunction. Talk to your rheumatologist to clarify what is exactly occuring. ...Read moreSee 1 more doctor answer
Arterial inflammatio: Lupus cerebritis is caused by blood vessels becoming inflamed, usually smaller blood vessels. Treatments are many, but steroids, methotrexate, benlysta, CellCept (mycophenolate mofetil) are options if simple Hydroxychloroquine does not prevent this. Steroids not been an ongoing thing. Many patients do well with "pulsing" large doses of steroids intravenously, usually three times. Presentations vary-neuropsychiatric! ...Read moreSee 2 more doctor answers