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Doctor insights on: Cml

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Dr. Julio Hajdenberg
58 doctors shared insights

Cml (Overview)

Chronic myelogenous leukemia (CML), is a type of blood cancer where the slow overgrowth of the immune cells of the blood leads to a weakened immune system, lymph node and spleen enlargement, fatigue from anemia, and easy bruising and bleeding.


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What sort of disease is chronic myelogenous leukemia (c.M.L.)?

What sort of disease is chronic myelogenous leukemia (c.M.L.)?

Bcr-abl: CML is a clonal disorder (cancer) of the white blood cells in the blood (= -emia part). Other leukemias include cll, aml, all, etc. CML is often diagnosed by testing on peripheral blood or bone marrow. The bcr-abl translocation (philadelphia chromosome) is found in cml. Treatment may be a variety of pills. The most common initial treatment has been gleevec (imatinib). Other drugs are available. ...Read more

Dr. Julio Hajdenberg
58 doctors shared insights

Cml (Overview)

Chronic myelogenous leukemia (CML), is a type of blood cancer where the slow overgrowth of the immune cells of the blood leads to a weakened immune system, lymph node and spleen enlargement, fatigue from anemia, and easy bruising and bleeding.


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What are the symptoms of chronic myelogenous leukemia?

Fatigue: Fatigue is the most common symptom. Examination may show an enlarged spleen. The diagnosis is suspected by blood testing and confirmed by bone marrow biopsy. ...Read more

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High deductible. Limited coverage of outpatient care. Would really help to know what tests, evaluations are required to diagnose chronic myelogenous leukemia and follow it after treatment.?

High deductible. Limited coverage of outpatient care. Would really help to know what tests, evaluations are required to diagnose chronic myelogenous leukemia and follow it after treatment.?

Nccn.org: Awful predicament. CML is one of the success stories with the new therapies, but proper follow up is important to assure optimal long term survival on the new oral agents. There are good patient assistance programs to assist with your medications. Review the web address above and CML page with your doc to plan the needed tests. ...Read more

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What are the tests for chronic myelogenous leukemia?

What are the tests for chronic myelogenous leukemia?

Blood, bone marrow: Common tests include blood review, floww cytometry, and a bone marrowe and biopsy. ...Read more

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What happens genetically that causes chronic myelogenous leukemia?

What happens genetically that causes chronic myelogenous leukemia?

Translocation: A big word but dna is always recombining when cells divide. In this case, a piece of dna from chromosome 9 moves over to chromosome 22 which essentially turns on a switch that produces an enzyme that promotes uncontrolled cell division and leukemia. Modern drugs are targeted to prevent the action of this enzyme. ...Read more

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How should I treat chronic myelogenous leukemia?

How should I treat chronic myelogenous leukemia?

By oncologist: This is a somewhat indolent form of leukemia which responds to treatment and can be carried for many years without major illenss. You could only have known about this if you had a bone marrow and blood test from your oncologist whose recommendations i would continue to follow. ...Read more

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What are the treatments for chronic myelogenous leukemia?

Multiple: There are medications called tyrosine kinase inhibitors. They block this enzyme and treat the leukemia. There are currently three on the market, imatinib, nilotinib and dasatinib. Other treatments include bone marrow transplant but rarely done now because these medications are available. Hope this helps. ...Read more

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Is chronic myelogenous leukemia classified as a genetic abnormality or a genetic disorder?

Yes.: CML = genetic abnormality or a genetic disorder? I'm not sure what the difference is, but i'll try to extend what i think you are asking. CML is an acquired genetic abnormality. It is not (generally) an inheritied genetic trait/disorder. ...Read more

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What is chronic myelogenous leukemia (cml)?

What is chronic myelogenous leukemia (cml)?

White cell cancer: The bone marrow cells that produce granulocytes (needed to fight infections) grow out of control and are present in large numbers in the blood and other organs. The disease is quite treatable these days because of targeted therapy and long lasting remissions are possible in most people. ...Read more

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What sort of disease is chronic myelogenous leukemia (c.M.L.)?

Bcr-abl: CML is a clonal disorder (cancer) of the white blood cells in the blood (= -emia part). Other leukemias include cll, aml, all, etc. CML is often diagnosed by testing on peripheral blood or bone marrow. The bcr-abl translocation (philadelphia chromosome) is found in cml. Treatment may be a variety of pills. The most common initial treatment has been gleevec (imatinib). Other drugs are available. ...Read more

Dr. Liawaty Ho
60 doctors shared insights

Chronic Myelogenous Leukemia (Definition)

there are two types of CML ,juvenile and adult . each manifests marked clinical ...Read more