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Doctor insights on: Clozaril Serotonin Dopamine Receptor Blocker

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If a certain meditation releases a lot of dopamine/serotonin, etc; is there a probability that overdoing it could down-regulate receptors in my brain?

If a certain meditation releases a lot of dopamine/serotonin, etc; is there a probability that overdoing it could down-regulate receptors in my brain?

Serontinergic: Receptors do down regulate when a medication is used, they up regulate when there is no seratonin. Down regulation of Dopamine receptors does occur in cases of abuse with cocaine, high dose amphetamine , etc, not with common medications for mood. Also people may have different levels of receptors without meds, thrill seekers needing more Dopamine release to feel a charge, . ...Read more

Receptor (Definition)

An organ, cell or molecule that accepts an outside signal and causes an internal change. Eyes receive light, touch receptors send messages to the brain when stimulated by pressure and estrogen receptors bind Estradiol causing responses of normal breast, ovary and uterus cells to rising and falling levels of the female steroid hormones. Most of the time "receptor" refers to one ...Read more


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High serotonin and low dopamine levels indicate what?

High serotonin and low dopamine levels indicate what?

Nothing: Don't waste your money on these kind of tests. It is how you feel, how you think, how you take care of yourself that matters. ...Read more

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How can I replenish dopamine and serotonin levels after a drug binge?

How can I replenish dopamine and serotonin levels after a drug binge?

You Can't: Mutual support such as Narcotics Anonymous can be helpful and life-saving for many people. Also seek help from a physician and/or counselor with experience with addiction. ...Read more

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Does coffee affects the levels of serotonin, noradrenaline and dopamine ?

Does coffee affects the levels of serotonin,  noradrenaline and dopamine ?

Yes: The caffeine in coffee blocks Adenosine receptors, which when activated make you tired and sleepy. This blockade also affects all major neurotransmitters, such as dopamine, acetylcholine, serotonin -- and in high doses, norepinephrine too. Dopamine effects are not in the exact same regions of the brain that other addictive substances affect, though. ...Read more

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Which part of the brain uses serotonin and dopamine?

Which part of the brain uses serotonin and dopamine?

Everywhere: Both are found throughout the brain, but more common in the limbic or emotional part of the brain ...Read more

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What do serotonin and dopamine have in common?

What do serotonin and dopamine have in common?

TwoNeurotransmitters: Serotonin is a neural transmitter primarily found in the gastrointestinal tract, platelets, and in the central nervous system. Dopamine is a neurotransmitter that helps control the brain's reward and pleasure centers. Dopamine also helps regulate movement and emotional responses, and it enables us not only to see rewards, but to take action to move toward them. ...Read more

Serotonin (Definition)

Serotonin is a chemical derived from the Amino Acid tryptophan and acts as a neurotransmitter (communicating ...Read more


Dr. Philip Greilich
219 doctors shared insights

Clozapine (Definition)

Clozapine is a serotonin-dopamine receptor blocker which is a kind of atypical anti-psychotic drug (drug ...Read more