Doctor insights on:
Clozapine Allergy In Children
Allergies occur when your immune system is triggered by envirionmental factors it should ignore--for example, pollen in the air, or dander on a cat or dog--and creates cells to fight against them. An allergic reaction typically causes itching, congestion, or drainage, and ...Read more
Strong antipsychotic: Clozaril/clozapine is an effective antipsychotic medication with many cautions and potential side effects requiring regular blood tests. It can be effective for severe or difficult to treat schizophrenia. Given the potential side effects and requirement of blood tests, many doctors try other, safer medications or combinations first. ...Read more
Yes: Don't do it. Please work with your prescribing provider to safely come off this medication. ...Read more
You can have a serious rebound of symptoms which may take long time to get under control again, Clozapine is the gold standard for addressing symptoms that didn't respond to other meds, so NEVER attempt to do that, ask your treating physician and work with him/her.
good luck and feel better ...Read more
Shouldn't: You shouldn't, if you do, you end up with a rebound of symptoms that can sometimes be harder to treat. Consult with your prescriber ...Read more
Yes: Clozapine is an antipsychotic medication that can cause movement problems to include extrapyramidal side effects. That said, it is typically less a problem in this medication compared with some older antipsychotic medications. But muscle stiffness, tremor, dyskinesia, and others are certainly possible. ...Read more
Can occur: These side effects would occur while taking Clozaril, but if you have stopped and instead suffer restless leg syndrome, would suggest checking iron metabolism, with ferritin level, and considering use of a dopamine agonist around the clock (suggest Neupro (rotigotine) patch). Talk to your doctor about these thoughts. ...Read more
No: Speak to your friend and feel free to call his/her physician. A true friend is ready to speak up when something like this happens. ...Read more
Please, I need to know, will the drooling side effect of clozapine go away? It's driving me crazy.
Drooling & Clozapine: Drooling is a known side effect of Clozapine and it may be dose-related -- meaning that you & your doctor can discuss whether a lower dose of Clozapine will still protect you from psychotic symptoms. If so, this may help the drooling go away. If this isn't feasible, your doctor can also consider medicines to combat this: clonidine, benztropine, amitriptylene, & terazosin are a few options. ...Read more
How well does lenditro work for nocturnal enuresis caused by clozapine? How long before bed time should I take it?
Contain oxybutynin: Oxybutynin is an anticholinergic which tends to relax bladders mooth muscle ; thus increase funtional bladder capacity ; decrease involuntary bladder contractions. However regular Oxybutynin only has a 4 - 6 hour window of action. You need long-acting or sustained release Oxybutynin either generic or Ditropan er if available where you live 10 -15mg or Detrol (tolterodine) la 4-8mg. Take just before going to bed. ...Read more
Clozaril (clozapine): Is an atypical antipsychotic approved for use in treatment-resistant schizophrenia & is also used off-label to treat bipolar disorders. It is very effective as long as close monitoring of white blood cell count is done routinely. Some reported side-effects are seizures, myocarditis, agranulocytosis, diabetes, weight gain. It is not indicated if seizures, liver disease or low blood count. ...Read more
Yes, however: Clozaril/clozapine is an effective antipsychotic medication with many cautions requiring regular blood tests. It can be effective for severe or difficult to treat bipolar disorder. Given the potential side effects and requirement of blood tests, many doctors try other, safer medications or combinations first. ...Read more
Overdo: In theory; but it s not indicated (off label) and hard to justify the risks involved (agranulocytosis, seizures, death) not to mention the monitoring required. It should not be an alternative. ...Read more
Depends upon the dose used. However, it is recommended that the medicine be weaned off as abrupt stoppage can lead to a seizure
spell. Check with your physician. ...Read more
No: Clozapine is considered a 2nd generation antipsychotic medication, typically used in schizophrenia, that antagonizes quite a few neurotransmitter receptors, eg Dopamine d1 & d4 plus serotonin 5ht2 & cholinergic muscarinic ones, too. It's a very effective drug when used under close observation but can only be prescribed under restricted distribution due high risk for agranulocytosis, etc. ...Read more
Yes, effects bel: Nervous system side effects have included drowsiness/sedation (39%), dizziness/vertigo (19%), headache (7%), tremor (6%), syncope (6%), disturbed sleep/nightmares (4%), restlessness (4%), seizures 3% /myoclonic movements, agitation (4%), rigidity (3%), akathisia (3%), confusion (3%), fatigue (2%), insomnia (2%), hyperkinesia (1%), weakness (1%), lethargy (1%), ataxia (1%), slurred speech. Ervo ...Read more
Talk to your doctor: Ability (aripiprazole) is a 2nd generation antipsychotic that is indicated (approved) for use in schizophrenia & bipolar disorder as well as an adjunct in major depression. Clozapine is also a 2nd generation antipsychotic w/limited approval due to a significantly greater side effect risk. Very rarely are two medications in same class used concomitantly, and then usually only by specialists. ...Read more
About 300-450mg but: Clozapine has some unique side effects that require very strict monitoring that must be adhered to. Most patients do end up with less or more than the equivalent amounts of the medication based on how the medication is tolerated, so, consult with your doctor. ...Read more
See ur Doctor: Stopping Clozapine is a Major decision in any treatment plan, it is taken very seriously by the treating physician and all risks and benefits are weighed carefully, it cant be done over the net, you have to see your prescribing physician and discuss with him the issue. Good luck and feel better ...Read more
Requires expert care:
Withdrawing from clozapine may come with *many* potential consequences. I hope you have someone with sufficient expertise to help with the process.
The anticholinergic withdrawal syndrome (AWS) is often described as flu-like malaise. Brain-permable anticholinergic meds like benztropine (Cogentin) or scopolamine would be reasonable treatments for AWS.
This should be undertaken w a psychiatrist. ...Read more
Since I started clozapine I've been very lethargic and drooling a waterfall. How long until it goes away?
I want o quit colzapine due to its side effects. I am currently on aripiprazole and clozapine. How should safely stop taking clozapine?
Taper: One should taper off of clozapine. However, you may need to add another similar medication to help with the symptoms clozapine is controlling. Discuss this with your doctor. ...Read more