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Doctor insights on: Clozapine Allergy In Children

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What is the definition or description of: Clozapine allergy?

What is the definition or description of: Clozapine allergy?

Clozapine Allergy: Clozaril (clozapine) is an antipsychotic medication used for the treatment of schizophrenia. Allergic reactions could include swelling of tongue, throat, lips, mouth, face, hives or difficulty breathing. ...Read more

Dr. John Chiu
2,630 Doctors shared insights

Allergies (Definition)

Allergies occur when your immune system is triggered by envirionmental factors it should ignore--for example, pollen in the air, or dander on a cat or dog--and creates cells to fight against them. An allergic reaction typically causes itching, congestion, or drainage, and ...Read more


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What is the definition or description of: Clozaril (clozapine) allergy?

What is the definition or description of: Clozaril (clozapine) allergy?

Clozaril allergy: Clozaril (clozapine) is an antipsychotic medication used for the treatment of schizophrenia. Allergic reactions could include swelling of tongue, throat, lips, mouth, face, hives or difficulty breathing. ...Read more

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Anyone out there taking clozapine (or clozaril)? What is it?

Anyone out there taking clozapine (or clozaril)? What is it?

Strong antipsychotic: Clozaril/clozapine is an effective antipsychotic medication with many cautions and potential side effects requiring regular blood tests. It can be effective for severe or difficult to treat schizophrenia. Given the potential side effects and requirement of blood tests, many doctors try other, safer medications or combinations first. ...Read more

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Should I go cold turkey off clozapine?

No: Coming off Clozapine should be done under medical supervision. ...Read more

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I am going cold turkey off clozapine, suggestions?

Yes: Don't do it. Please work with your prescribing provider to safely come off this medication. ...Read more

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What could happen if I went cold turkey off clozapine?

Serious rebound: You can have a serious rebound of symptoms which may take long time to get under control again, Clozapine is the gold standard for addressing symptoms that didn't respond to other meds, so NEVER attempt to do that, ask your treating physician and work with him/her.
good luck and feel better ...Read more

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I was wondering what would happen if I went cold turkey off clozapine?

Shouldn't: You shouldn't, if you do, you end up with a rebound of symptoms that can sometimes be harder to treat. Consult with your prescriber ...Read more

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Could clozapine cause movement problems?

Yes: Clozapine is an antipsychotic medication that can cause movement problems to include extrapyramidal side effects. That said, it is typically less a problem in this medication compared with some older antipsychotic medications. But muscle stiffness, tremor, dyskinesia, and others are certainly possible. ...Read more

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Is clozapine ever used for treating chronic pain?

Is clozapine ever used for treating chronic pain?

Maybe: I personally do not use anti-psychotics for pain management. I could not say that it is never used, as I am sure some docs use this and other anti-psychotics for pain management, but this is not the indication for the drug. ...Read more

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Can clozaril (clozapine) cause akathisia, restlessness?

Can clozaril (clozapine) cause akathisia, restlessness?

Can occur: These side effects would occur while taking Clozaril, but if you have stopped and instead suffer restless leg syndrome, would suggest checking iron metabolism, with ferritin level, and considering use of a dopamine agonist around the clock (suggest Neupro (rotigotine) patch). Talk to your doctor about these thoughts. ...Read more

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Clozapine is making friend act weird, is that a normal side effect?

Clozapine is making friend act weird, is that a normal side effect?

No: Speak to your friend and feel free to call his/her physician. A true friend is ready to speak up when something like this happens. ...Read more

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Please, I need to know, will the drooling side effect of clozapine go away? It's driving me crazy.

Please, I need to know, will the drooling side effect of clozapine go away? It's driving me crazy.

Drooling & Clozapine: Drooling is a known side effect of Clozapine and it may be dose-related -- meaning that you & your doctor can discuss whether a lower dose of Clozapine will still protect you from psychotic symptoms. If so, this may help the drooling go away. If this isn't feasible, your doctor can also consider medicines to combat this: clonidine, benztropine, amitriptylene, & terazosin are a few options. ...Read more

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How well does lenditro work for nocturnal enuresis caused by clozapine? How long before bed time should I take it?

How well does lenditro work for nocturnal enuresis caused by clozapine? How long before bed time should I take it?

Contain oxybutynin: Oxybutynin is an anticholinergic which tends to relax bladders mooth muscle ; thus increase funtional bladder capacity ; decrease involuntary bladder contractions. However regular Oxybutynin only has a 4 - 6 hour window of action. You need long-acting or sustained release Oxybutynin either generic or Ditropan er if available where you live 10 -15mg or Detrol (tolterodine) la 4-8mg. Take just before going to bed. ...Read more

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Is clozapine (clozaril) good for bipolar?

Is clozapine (clozaril) good for bipolar?

Clozaril (clozapine): Is an atypical antipsychotic approved for use in treatment-resistant schizophrenia & is also used off-label to treat bipolar disorders. It is very effective as long as close monitoring of white blood cell count is done routinely. Some reported side-effects are seizures, myocarditis, agranulocytosis, diabetes, weight gain. It is not indicated if seizures, liver disease or low blood count. ...Read more

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Clozapine (clozaril) for good for bipolar?

Yes, however: Clozaril/clozapine is an effective antipsychotic medication with many cautions requiring regular blood tests. It can be effective for severe or difficult to treat bipolar disorder. Given the potential side effects and requirement of blood tests, many doctors try other, safer medications or combinations first. ...Read more

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How can I get off clozaril (clozapine)?

Carefully: Clozaril (clozapine) is a very potent medication. If you are taking this be careful about discontinuing it. I would suggest you talk to your doctor about the advisability of stopping this medication. You may need to switch to a different medication. ...Read more

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Can clozaril (clozapine) be used to treat severe insmnia?

Overdo: In theory; but it s not indicated (off label) and hard to justify the risks involved (agranulocytosis, seizures, death) not to mention the monitoring required. It should not be an alternative. ...Read more

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Can you advise me on going cold turkey off clozapine?

Can you advise me on going cold turkey off clozapine?

Stopping Clonazepam: Depends upon the dose used. However, it is recommended that the medicine be weaned off as abrupt stoppage can lead to a seizure
spell. Check with your physician. ...Read more

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Is clozapine a benzodiazepine?

Is clozapine a benzodiazepine?

No: Clozapine is considered a 2nd generation antipsychotic medication, typically used in schizophrenia, that antagonizes quite a few neurotransmitter receptors, eg Dopamine d1 & d4 plus serotonin 5ht2 & cholinergic muscarinic ones, too. It's a very effective drug when used under close observation but can only be prescribed under restricted distribution due high risk for agranulocytosis, etc. ...Read more

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Is clozapine (clozaril) benzodiazepine?

Is clozapine (clozaril) benzodiazepine?

Dibenzodiazepine: Clozaril/clozapine is not a benzodiazepine like lorazepam/ativan or alprazolam/xanax. Its chemical structure is a dibenzodiazepine and it is a 2nd generation antipsychotic. ...Read more

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Is it possible for clozapine to cause movement problems?

Is it possible for clozapine to cause movement problems?

Yes, effects bel: Nervous system side effects have included drowsiness/sedation (39%), dizziness/vertigo (19%), headache (7%), tremor (6%), syncope (6%), disturbed sleep/nightmares (4%), restlessness (4%), seizures 3% /myoclonic movements, agitation (4%), rigidity (3%), akathisia (3%), confusion (3%), fatigue (2%), insomnia (2%), hyperkinesia (1%), weakness (1%), lethargy (1%), ataxia (1%), slurred speech. Ervo ...Read more

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Can I take clozapine and Abilify (aripiprazole) together safely?

Can I take clozapine and Abilify (aripiprazole) together safely?

Talk to your doctor: Ability (aripiprazole) is a 2nd generation antipsychotic that is indicated (approved) for use in schizophrenia & bipolar disorder as well as an adjunct in major depression. Clozapine is also a 2nd generation antipsychotic w/limited approval due to a significantly greater side effect risk. Very rarely are two medications in same class used concomitantly, and then usually only by specialists. ...Read more

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What amount of clozapine is roughly equivalent to 6 mg risperidone?

What amount of clozapine is roughly equivalent to 6 mg risperidone?

About 300-450mg but: Clozapine has some unique side effects that require very strict monitoring that must be adhered to. Most patients do end up with less or more than the equivalent amounts of the medication based on how the medication is tolerated, so, consult with your doctor. ...Read more

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How long does it take to get used to the sedating side effects of clozapine?

How long does it take to get used to the sedating side effects of clozapine?

Klonopin (clonazepam): Sedating effects can last up to one week, depending on dose and severity of underlying anxiety. ...Read more

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Which drug is best to stop clozapine and to reduce the withdrawal cholinergic rebound?

See ur Doctor: Stopping Clozapine is a Major decision in any treatment plan, it is taken very seriously by the treating physician and all risks and benefits are weighed carefully, it cant be done over the net, you have to see your prescribing physician and discuss with him the issue. Good luck and feel better ...Read more

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Do you know which drug is best to stop clozapine, and to reduce withdrawal cholinergic rebound?

Do you know which drug is best to stop clozapine, and to reduce withdrawal cholinergic rebound?

Requires expert care: Withdrawing from clozapine may come with *many* potential consequences. I hope you have someone with sufficient expertise to help with the process.
The anticholinergic withdrawal syndrome (AWS) is often described as flu-like malaise. Brain-permable anticholinergic meds like benztropine (Cogentin) or scopolamine would be reasonable treatments for AWS.
This should be undertaken w a psychiatrist. ...Read more

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Since I started clozapine I've been very lethargic and drooling a waterfall. How long until it goes away?

Since I started clozapine I've been very lethargic and drooling a waterfall. How long until it goes away?

Clozapin: Lethargy is dose-related. Side effects need to be reviewed with your prescribing doctor. ...Read more

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I want o quit colzapine due to its side effects. I am currently on aripiprazole and clozapine. How should safely stop taking clozapine?

Taper: One should taper off of clozapine. However, you may need to add another similar medication to help with the symptoms clozapine is controlling. Discuss this with your doctor. ...Read more

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What are treatments for clozapine-induced ocd?

What are treatments for clozapine-induced ocd?

SSRI: OCD whther it is drug induced or spontaneous is treated with SSRI's such as Fluvoxamine or Sertraline. Sometimes decreasing the dosage of Clozapine helps. Good luck and feel better. ...Read more

Clozapine Allergy (Definition)

Clozaril (clozapine) is an antipsychotic medication used for the treatment of schizophrenia. Allergic reactions could include swelling of tongue, throat, lips, mouth, face, ...Read more


Dr. Heidi Fowler
223 Doctors shared insights

Clozapine (Definition)

Clozapine is a serotonin-dopamine receptor blocker which is a kind of atypical anti-psychotic drug (drug ...Read more