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Doctor insights on: Clostridium Difficile Antigen Positive Toxin Negative

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Clostridium difficile toxin b gene present clostridium dificile antigen presen. Would u no how severe the c diff is?

Clostridium difficile toxin b gene present clostridium dificile antigen presen. Would u no how severe the c diff is?

Have diarrhea or no?: C.Difficile is pathogenic in older children & adults (whose colonic microflora are altered by antibiotics, chemotherapy, salmonella/shigella). C.Diff causes diarrhea w/pseudomembranous & other colitis, complicates inflammatory bowel disease, causes fulminant transmural extension, perforation with peritonitis, toxic megacolon. Treatment, & confirmation of post-treatment eradication, is recommended.

Toxin (Definition)

Poisonous substance produced within living cells or organisms;man-made substances created by artificial processes are thus excluded. The term was first used by organic chemist ludwig brieger (1849–1919). For a toxic substance not produced within living organisms, "toxicant" and "toxics" are also sometimes used.[citation needed]. Toxins can be small ...Read more


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Had clostridium difficile, toxin a and b. Was cured and test show all are negative. Diarrea continues what can I do?

Had clostridium difficile, toxin a and b. Was cured and test show all are negative. Diarrea continues what can I do?

Retest: If you had confirmed c diff and diarrhea has returned following treatment then you likely have recurrence. The stool studies are not 100% accurate.

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What is the definition or description of: clostridium difficile toxin?

Toxin: Clostridium difficile is a slow growing, spore forming bacterium that can cause infection in humans, especially in the setting of antibiotic use. The toxin produced causes a colitis, resulting in diarrhea that is often bloody.

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Is there a medical cure for clostridium difficile?

Is there a medical cure for clostridium difficile?

Yes. A few options..: Most cases of c. Dif colitis can be treated by oral/iv metronidazole, oral vanocomycin, and maybe add of Cholestyramine resins. Newer agent Dificid (fidaxomicin) is effective, but $$$. Bacitracin has some use, but not standard of care. For persistent/recurrent cases after treatments with above, a stool-transplant (yes, stool transplant--u read it right) can be done. Consult your doc. Good luck.

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What are the symptoms of c- diff (clostridium difficile)?

Symptoms: Symptoms include abdominal pain which can be dull or crampy, watery diarrhea, nausea/vomiting, fevers, or chills. These symptoms are not different than most diarrheas which are viral in origin (norovirus for example) and it can be tough to differentiate.

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Clostridium difficile in carpet. Should it be replaced in my home?

Clostridium difficile in carpet. Should it be replaced in my home?

An unusual find...: I'm assuming your carpeting has been tainted by stool from an infected individual (you mentioned your mother has the bacteria). She needs appropriate treatment to eradicate the infection. Until cleared, she should not handle food, & all contacts must wash hands well. A thorough steam-cleaning of your carpet should suffice, but you may want to consider hardwood if she is prone to incontinence.

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Can clostridium difficile colitis Get Cured. Or just Treated? And is it Cancerous Later On?

Can clostridium difficile colitis Get Cured. Or just Treated? And is it Cancerous Later On?

Cured: It is an infectious process and can be eliminated completely with appropriate therapy. As far as we know it does not cause any type of cancer.

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Chances of someone getting clostridium difficile colitis from cefprozole? And how would they know?

Pretty Low: I think u r referring to cefprozil, a 2nd generation cephalosporin antibiotic. In theory any antibiotic can place you at risk for a clostridium difficile infection, but is much more likely in an elderly, hospitalized patient who might have a weakened immune system. Although Cefprozil is not particularly associated with c diff, using a probiotic or eating yogurt will help. If c diff, severe diarrhea.

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How can you get rid of c.Diff. (clostridium difficile)?

Agree with above: The infection has a propensity to relapse hence, fecal matter transplantation should be considered in some cases to restore gut microbiome. Would try not taking antibiotics if can be avoided.

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What is clostridium difficile infection rate of spread?

Depends: It depends on how sick the initial patient is, how sick the exposed patients are, and how aware of infection control the care providers are. In wards where it is allowed to run wild, it can spread throughout the entire ward in a matter of days.

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What sort of disease is a clostridium difficile infection?

Colon infection: Clostridium difficile infection is a growing epidemic where the colon is infected by a bacteria called, you guessed it, clostridium difficile. Although some people may be asymptomatic, it usually causes diarrhea and can lead to a life-threatening condition called megacolon. Treatment of late has become more and more complicated due to antibiotic resistance. Seek an md if you have this.

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Clostridium difficile and melanoma, can you tell me about this?

Bacteria and a cance: Clostridium difficile is a bacteria that causes severe diarrhea in patients that are exposed to the pathogen. It also arises in patients that are taking antibiotics for other reasons. Melanoma is a type of skin cancer. Melanoma is also the deadliest type of skin cancer as it is able to travel to different sites of the body. I am not sure of a link between the two.

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What is a clostridium difficile infection and how does it occur?

What is a clostridium difficile infection and how does it occur?

Abx complication: An infection resulting from antibiotic use that can cause diarrhea and other colonic problems. It requires treatment with either Metronidazole or oral vancomycin.

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I have Crohn's disease? Am I more susceptible to clostridium difficile infections?

Not really: It is not that you're more susceptible, it's that you are more likely to be treated with antibiotics because of your condition. As c diff is typically a post-antibiotic illness, you are more likely to experience it. But it's not directly because of crohn's.

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Can taking probiotics prevent clostridium difficile infections?

Yes.: Studies have shown that probiotics can prevent c.Diff infections and other antibiotic associated complications like diarrhea. Best way to prevent c.Diff infections is good hand washing if you visit a hospital or nursing home. Also by not taking antibiotics for viral illnesses like bronchitis and sinusitis. You increase your risk of c. Diff when you take abx for things like these.

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What's clostridium difficile?

Colitis: This organism causes colitis in patients given antibiotis. The antibiotics kill the normal flora in the colon and allow c diff to grow. It releases a toxin that causes necrosis and ulcers in the colon. The infection may be acquired in the hospital and sperad by hospital, on their hands, from one patient to another.

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What can transmit clostridium difficile?

Fecal contamination: C diff may be transmitted from one patient to an other on the hands of hospital workers if they do not wash hands between patients.

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What are the symptoms of clostridium difficile?

Diarrhea: Most often following antimicrobial therapy (or sometimes cancer chemotherapy), the patient develops watery diarrhea which often has a mousy, horse barn like odor. There can be fever and sometimes a quite elevated white blood cell count. Some strains, in the last few years, seem to be hyper producers of toxin with more severe symptoms likely.

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Antigen (Definition)

Antigens are chemicals which upon exposure to the surface or inside of the body, will cause a reaction term allergic. Many substances will do this and allergic response is the basis for immunological protection for ...Read more


Dr. Stephen Scholand
449 Doctors shared insights

Clostridium Difficile (Definition)

C. Diff, it is a spore forming bacillus that when the micro environment of the colon is modified by antimicrobials, it can germinate and elaborate a toxin causing pseudo membranous colitis, ...Read more