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Doctor insights on: Clofibrate

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Dr. Fred McCurdy
12 doctors shared insights

Clofibrate (Overview)

Clofibrate is a fibrate which is a kind of cholesterol/lipid lowering agent (cardiovascular drug).


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Why is clofibrate contraindicated in patients with renal failure?

Why is clofibrate contraindicated in patients with renal failure?

Clofibrate: Clofibrate is a lipd lowering drug that is metabollized in the liver. Those metabolites are excreted in the kidney. When renal failure/insufficiency happens, the drug itself as well as its metabolites build up in the blood. High concentrations of these metabolites can lead to serious side effects including death. So, don't take Clofibrate if you have renal disease. ...Read more

Dr. Fred McCurdy
12 doctors shared insights

Clofibrate (Overview)

Clofibrate is a fibrate which is a kind of cholesterol/lipid lowering agent (cardiovascular drug).


2

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Why is chlordiazepoxides, diazepam, clofibrate, barbiturates contraindicated in renal failure?

Why is chlordiazepoxides, diazepam, clofibrate, barbiturates contraindicated in renal failure?

Impaired elimination: All drugs that are taken are eventually metabolized and eliminated from the body. Although liver enzymes perform the bulk of metabolizing of these agents, elimination of the drug and their metabolites relies, to varying degrees, on the kidney. If the kidneys are failing, elimination is impaired, and a toxic buildup of the drug and/or its metabolites is possible. ...Read more

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Why is clofibrate contraindicated in patients with renal failure?

Clofibrate: Clofibrate is a lipd lowering drug that is metabollized in the liver. Those metabolites are excreted in the kidney. When renal failure/insufficiency happens, the drug itself as well as its metabolites build up in the blood. High concentrations of these metabolites can lead to serious side effects including death. So, don't take Clofibrate if you have renal disease. ...Read more

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Why is chlordiazepoxides, diazepam, clofibrate, barbiturates contraindicated in renal failure?

Impaired elimination: All drugs that are taken are eventually metabolized and eliminated from the body. Although liver enzymes perform the bulk of metabolizing of these agents, elimination of the drug and their metabolites relies, to varying degrees, on the kidney. If the kidneys are failing, elimination is impaired, and a toxic buildup of the drug and/or its metabolites is possible. ...Read more

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Am I dying?

Am I dying?

We all are: A 3-word question with no details... well, life is short on Earth, regardless of whether a person lives 3 days, 3000 days, or 30,000 days. It is not length of one's life that matters, but the quality of the life lived. The goal is not to live a long life, but to live a good life. Even if a person makes it all the way to age 82, that's only 30,000 days. ...Read more

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I have cold?

I have cold?

Symptoms?: The most common symptoms of a cold are sneezing, running nose, congestion and scratchy throat. Additional symptoms can be coughing, headaches, mucus dripping down the back of the throat, loss of appetite and fever (in children). ...Read more

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What is asp?

What is asp?

In acupuncture an: Asp is an acupuncture semi-permanent needle. They are made in germany & come in stainless steel, gold, silver & titanium. They are used for auricular (ear) acupuncture. They are usually referred to as "asp's". ...Read more

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I have cold?

I have cold?

Cold: Tips: sore throat – gargle with warm salt water (1/2 tsp salt in 8 oz of water). Get strep test/culture if very sore. Congestion – saline nose drops or netti pot. For anti-inflammatory effect & mobilizing mucus- homemade chicken noodle soup. Hydrate- lots of water/clear broth/ add honey & a small amt. Of lemon juice to chamomile tea.. Fever/ pain – Acetaminophen / nsaid’s rest! ...Read more

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