Doctor insights on:
Cll Lymphoma Diagnostic Panel
Are lymphocyte rich hodgkin's lymphoma and nodular lymphocyte predominant hodgkin's lymphoma the same?
Have low platelet, splenomegaly,high LDH, B2M and C-reactive protein, normal marrow, cytometry and pet scan,normal WBC, possible CML? fish ?PCR need?
Autoimmune: Sounds like the good news is cancer had been ruled out. The tests and physical problems you listed can have many causes. Infections especially viral, are a cause. Medications or environmental exposures are possible. Autoimmune diseases are also a big possibility. Your next step should be a rheumatologist. ...Read more
+ ANA test, severe neutropenia with large granular lymphocytes, high monocytes and lymphocytes. Osteoarthritis. Bone marrow biopsy negative. Idea?
Multiple enlarged axilla lymph nodes (largest is 2cm) normal chest xray.High Wbc. High absolute neutropolis.High lymphocytes. Lymphoma Cancer?
Dont assume cancer: never make assumptions regarding cancer...you are right to be concerned and you should pursue further work-up...this will include a history and complete exam with possible further x-rays....the enlarged nodes could represent infection and not cancer...be prepared for biopsy to make final diagnosis ...Read moreSee 1 more doctor answer
Reed-Sternberg: Cell, usual logical predictable spread. Nhl may be cd-20+ & b-cell, less predictable, wide ranging prognosis, from chronic & long to quite aggressive. Both treate with multi-aget chemo + rituxin in nhl. ...Read more
Docs overlooking lymphoma? Months w/ab pain, rectal blood (cscope ok), lymph pain, non-healing acne, episodic fuo. Neg mono test. Latest labs = high ldh, high lipase, low globulin, pos for atyp wbcs
.: I'm not exactly sure what you mean by lymph pain. But if you are having episodes of fevers and chills, unexplained abdominal pain for months, high ldh, this could warrant a ct scan with contrast (if kidneys okay) to look for a cause. Could be lymphoma but most probably not as lymphoma is not that common. Talk to your doctor. ...Read moreSee 1 more doctor answer
Likely for leukemia: Oftentimes leukemias can be picked up on routine CBC since it is a cancer of the blood and causes abnormal values of your red and white blood cells to appear. Lymphomas do not always affect the blood in a way that would be picked up on cbc. All leukemias however will not be picked up on routine CBC and CBC alone will not tell you what kind of leukemia specifically one might have. ...Read moreSee 1 more doctor answer
Adult male,bone marrow biopsy show Erythroid hyperplasia
RBC borderline on high side,thrombocytopenia fluctuate,
Splenomegaly,negative for infections.
CBC Results: If you can send us the complete blood count (CBC) report which includes Hb, WBC, Platelet counts done from 2 different dates, we can tell you if there is anything serious or how to manage your concerns. WE need to know the number of platelets(Count). RBC numbers are not useful...instead we use hemoglobin as a better test to reflect any problems with RBCs. ...Read more
Is afirma thyroid fna analysis-molecular marker test by veracyte any good for diagnosing papillary thyroid cancer?
Pathologic diagnosis....Resected thymus shows reactive b cell hyperplasia vs low grade b cell lympho proliferative disorder. Is this lymphoma?
Could be...: Certain lymphomas grow so slow that sometimes it is difficult for the pathologist to make the call between malignant or not. I suspect they may do additional work on the specimen and that your doctor will evaluate you further with labs, additional scans or another biopsy. If you have not seen a hematologist, maybe this is the time. Don't panic, just follow up his/her lead. Best to you. ...Read more
CBCj, flow cytometry: Leukemia is suspected when abnormal cells our found in the blood, or when blood counts are very low. The first test is the CBC (complete blood count). If abnormal cells are in the blood, they can be identified by flow cytometry, which analyzes compounds on the surface of blood cells. The definitive test otherwise is a bone marrow aspirate and biopsy, usually taken from the pelvic bone. ...Read more
Diagnosis. B.Cell non hodgkin, s lymphoma favor burkitt, s lymphoma. This us the result of biopsy taken during appendicectomy. D20 positive and tdt neg?
CD20 is a B-Cell: Marker hence the assignment of a b-cell nhl. Tdt is an immunohistochemical stain used to classify blood cells. Burkitt's is a very aggressive process -- get started on a plan with a hematologist straight away. ...Read more
CBP, ESR, Serum Iron, TIBC and identified
RBC Morphology : Microcytic- Hypochromic smear seen, Anisocytosis-Poikilocytosis. what test covers etiology?
Mantle Cell Lymphoma: ...is a type of non Hodgkin's lymphoma characterized by the genetic rearrangement of two chromosomes. This causes an abnormal fusion of two genes: Immunoglobulin (IgH) and Cyclin D1. Molecular studies that can detect this abnormality includes either FISH or RT-PCR. Flow cytometry is also good at identifying abnormal cells based on cell surface antigen expression. ...Read more
No: Elevated ESR and CRP are markers of inflammation, not cancer. For good health - Have a diet rich in fresh vegetables, fruits, whole grains, low fat milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form. Practice safe sex. ...Read more
No: Ldh may be high in lymphoma, but may not be. There are many laboratory and other tests used in the initial staging and prognostic testing for lymphoma. Also some tests are used before initial treatment because of concern of viral reactivation -- eg hiv, hepatitis studies. ...Read moreSee 2 more doctor answers
Sampling error: Fine needle aspirate of lymph nodes are not ideal for ruling out abnormal findings. Especially, with lymphomas there may be areas within the ln that are not involved and sampling of these areas may be misleading. Excisional biopsy is the gold standard, as it allows for assessment of individual cells and architecture of lymph node and adequate tissue for specialty workup. ...Read moreSee 1 more doctor answer
Wbc platelets absolute lymphs all came back high for 3rd time. Dr.says she is gonna continue to do test 1 a month. Why? Whats wrong? CLL or lymphoma?
More info needed: There is not enough info to determine the problem. Why were the blood tests done. Any symptoms or physical examination findings? We're the possinpble causes of the problems discussed with the health care provider? ...Read more
I have chronic lymphoproliferative disorder w/cll vs follicular lymphoma. Is it safe to get a shingles vaccination?
Probably: The degree of immunosuppression the average patient with cll has isn't bad enough to worry about getting disseminated zoster infections from the vaccine, but your physicians know your particular condition and how healthy or sick your immune system is. Ask them, especially your oncologist. ...Read more
Only sometimes...: I agree cll is not curable for most patients. For some patients who are robust, a consultation at a marrow /stem cell transplant center is warranted as there are investigational approaches that have helped some patients, some who appear cured. A note of caution- bone marrow transplant is the riskiest thing one can do to try to treat this disease and may lead to earlier death though. ...Read moreSee 3 more doctor answers
Depends on stage: For the patient with early stge cll the treatment is only observatio, meaning no therapy. When the disease stage advances or complications such as infections or low blood counts develop, at that point chemotherapy is started. Type of chemo depends on patient age, activity and can range from oral pills to combination regimens. ...Read more
Need to see all the : Results. How high is the count? What does the blood smear look like? A mild elevation of monocytes probably is not indication of any disease. Please note that all lab results need to be interpreted in the clinical context and your doctor is in the best position to do that. ...Read more
Possible!: I think you are referring to rai stage 0. This means you have elevated lymphocytes but with no enlarged lymph nodes or spleen. If not done, you would need ct scan to check for enlarged spleen which can cause bloating and feeling full quickly. However, these symptoms are atypical and less likely to be directly related to cll. Check with your oncologist! ...Read more
My cousin will be starting chemo for cll. Is it usual to have more of the protien than the chemo?
You mean protein?: Not sure what you are talking about. Please clarify. ...Read more
Have cll stage 0 recently diagnosed . Just lately have pain and abdomen is sensitive, left and middle of abdomen. Is ths related ?
My Surgical Pathology Report shows I have CLL. CD38 was one of the markers analyzed and there was nothing wrong with it, is this good??
All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Talk to the doctor who ordered the tests. Having said that your results are good. You may wish to read a rather technical paper at this site.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3574275/ ...Read more
Nothing: The indication for cll therapy are the following: stage 3 (hemoglobin <10), stage 4 (platelets<100, 000). A rapid lymphocyte doubling time is also a reason. It should not be treated at rai stage 0 or 1. It is not curable, so treatment is given only when needed. If the leukemia starts bothering the patient, then time to treat the leukemia. Hope this helps. ...Read more
Yes.: Smudge cells are cells that are extremely fragile and easy to disrupt the cell membrane when making a blood smear. Therefore, if the cell is disrupted it can be very hard to identify what kind of cell it is. The most common and well known disease with smudge cells is cll. However, many other hematologic diseases also have smudge cells. Further testing is needed to be sure what cells are there. ...Read more
Additional : It will be up to you ultimately to decide. However, it is not our intention to replace your primary oncologist- in any case. As written on the disclaimer - answers on healthtap are not intended for individual treatment, prescription or diagnosis. Yes, in my opinion, it is always the best to ask and drect all your questions to your primary oncologist. ...Read moreSee 1 more doctor answer
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