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Doctor insights on: Clark Staging Melanoma

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Nodular melanoma prognosis?

Nodular melanoma prognosis?

Melanoma prognosis: It's hard to tell based on no information provided. The depth of melanoma involvement and the size of the tumor are needed to prognosticate. ...Read more

Staging (Definition)

Many diseases have specific treatments based on their severity. A disease can have certain criteria to determine their severity and applying this criteria to determine how advanced the disease state is called staging. Most commonly this is applied to cancer, and be determining how far the cancer has spread locally and/or to distant sites a stage of cancer can be ...Read more


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Describe breast cancer staging according tnm?

Describe breast cancer staging according tnm?

Tumor,Nodes,Mets: The t, n, m system classifies breast cancers based upon tumor size(t), lymph node status(n), and presence of cancer elsewhere in the body(m). Stage i is limited to small cancers +/- microscopic ln disease. Stage ii describes tumors 2-5cm +/- ln disease. Stage iii is for more advanced tumors (>5cm, skin/chest wall involvement) +/- multiple/distant ln. Stage IV describes metastatic disease. ...Read more

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Colon surgery:tumor size=2cm.Pathologic staging(pt3, n1b, mx).2/17 lymph nodes show metastatic.Margins of resection free of carcinoma.Need chemotherapy?

Colon surgery:tumor size=2cm.Pathologic staging(pt3, n1b, mx).2/17 lymph nodes show metastatic.Margins of resection free of carcinoma.Need chemotherapy?

Yes: Chemotherapy regimens based on the drug Fluorouracil (5-fu) have been part of the treatment for high-risk stage ii or stage iii colon cancer. Many clinical trials have shown that these regimens improve overall survival primarily by reducing the high risk of recurrence within the first two years after surgery. ...Read more

Dr. Liawaty Ho Dr. Ho
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Breast cancer staging according TNM means what?

Dr. Liawaty Ho Dr. Ho
3 doctors agreed:
Breast cancer staging according TNM means what?

TNM breast cancer: Tnm is one of the staging system commonly used for cancer. It stands for t-tumor ( the size of the tumor- the bigger is the tumor the higher is the stage) ; n- nodal status ( involvement to the lymph glands) - and m- presence of metastatic disease to the distant organ. See more here: http://cancer.Gov/cancertopics/wyntk/breast/page7. ...Read more

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What is metastatic melanoma?

What is metastatic melanoma?

Skin cancer: In its most typical form, melanoma is a cancer that originates in cells of the skin called melanocytes. In some cases melanoma can spread to other organs from the skin. When it spreads, it is called metastatic melanoma. ...Read more

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What is melanoma skin cancer?

What is melanoma skin cancer?

Aggressive cancer: Melanoma develops from melanocytes cells of the lower layers in the skin. These cells produce pigments and the color of skin. When they form into cancer it can grow radially and deeply which can be dangerous as it can subsequently spread to other areas of the body. There are genetic predispositions as well as ultraviolet radiation exposure and sunburns are risk factors. ...Read more

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Stage 2B IDC breast cancer, her2+/ER/PR+Neoadjuvant taxol, (paclitaxel)A/C,lumpectomy,rads, lymphovascular invasion. What does this mean for prognosis & follow up?

Prognosis fair: Stage IIb breast cancer is usually palpable at 2-5 cm. and at time of procedure to remove lesion, sentinel nodes are + suggesting axillary dissection and reason for neoadjuvant therapy. Lymphovascular invasion increases chance for recurrence. With Her2+ Herceptin (trastuzumab) with chemo should be used and PET/CAT needed to assure met foci not missed in distal organs. Carful follow up needed. ...Read more

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Is metastatic squamous cell carcinoma genetic?

Is metastatic squamous cell carcinoma genetic?

Genetic component?: There could be genetic component to a squamous cell cancer, although the exact implications on treatment aren't known. Obviously if there is a strong family history of cancers, or if it strikes someone who is young and/or a non smoker/drinker i would suspect a strong genetic contribution. Without more details, it is hard to say with any certainty. ...Read more

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Is renal cell carcinoma stage 4 an aggressive cancer?

Is renal cell carcinoma stage 4 an aggressive cancer?

Stage 4 : Stage 4 renal cell carcinoma usually means that the cancer has spread to other parts of the body. At this stage, the cancer is consider very aggressive. www.peedoc.com @drhtay. ...Read more

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What is breast cancer sentinel node micro metastases?

What is breast cancer sentinel node micro metastases?

Spread of cells: Micrometastasis means that a few tumor cells have left the breast tumor and traveled to the lymph nodes under the arm. In most cases, this is treated as a negative lymph node. I encourage you to review your pathology report with your surgeon and oncologists (ideally they are communicating with each other through a meeting called a tumor board). ...Read more

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Is melanoma cancer curable/reversible?

Is melanoma cancer curable/reversible?

Very curable: In its early stages. Once it has spread from the primary site to other organs, the prognosis is much worse. Early treatment is key to a good outcome. ...Read more

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What are the survival statistics for breast cancer invasive ductal carcinoma?

What are the survival statistics for breast cancer invasive ductal carcinoma?

It depends on many f: Most women with localized breast cancer do very well and there is high cure rate. Overall 75%-80% of breast cancers are curable. But you need to know what stage of cancer it is? You should also know what subtype(there are 3 different types) of breast cancer it is. Further there is the matter of what type of adjuvant therapy(post surgery treatment) was used. I'am sure your oncologist can answeryr. ...Read more

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Is metastatic melanoma preventable?

Is metastatic melanoma preventable?

Yes and No: Certain genetic conditions may predispose someone to malignant melanoma. But there are certainly things that can be done to boost one's immune system to fight cancers. And those with irregular moles should be seen at least yearly by their doctor or dermatologist to remove suspicious moles. Therefore, preventing a metastatic process. ...Read more

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My mum 67 was diagnosed with metastatic caecal adenocarcinoma, aggressive stage 4 cancer.She's on folfox. Life expectancy??

My mum 67 was diagnosed with metastatic caecal adenocarcinoma, aggressive stage 4 cancer.She's on folfox. Life expectancy??

Varies from months/y: The overall survival of stage 4 colon cancer varies from 1 to 3 years. Most patients have at least 2 years if their tumor responds to chemo. If you tumors regresses after chemo, it may even be surgically removable in which case long term survival(even a cure) can be possible. Ask more questions to your treating oncologist. ...Read more

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Why does basal cell carcinoma have better prognosis than malignant melanoma?

Why does basal cell carcinoma have better prognosis than malignant melanoma?

Ability to travel: Basal cell carcinoma usually is limited to the site of disease. While it is possible for basal cell to metastasize it is very rare. In contrast melanoma travels through the lymphatic system and can form tumors in any location of the body. ...Read more

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Is stage 3c breast cancer curable?

Is stage 3c breast cancer curable?

Yes: ...In theory, with aggressive multi modality therapy (surgery plus chemo plus radiation +/- hormones +/- herceptin). The risk of relapse is high but you do all you can and hope for the best. If this is about you, fight well and best wishes. ...Read more

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What characterizes early stage squamous cell carcinoma?

What characterizes early stage squamous cell carcinoma?

Nothing: Even in the lung, squamous cell carcinomas are usually silent until they have become large enough to cause coughing up of blood -- one of the common ways in which it announces itself. On the skin, of course, a growing mass with a rough surface is (depending on how it looks) likely to be a squamous skin cancer; these are usually easy to cure. Good luck. ...Read more

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How is stage IV breast cancer different from stage III breast cancer?

How is stage IV breast cancer different from stage III breast cancer?

Location: In stage iii, the cancer still hasn't spread far beyond the breast and nearby lymph nodes. However, in this stage there typically are many lymph nodes involved or the tumor is so large it extends to the chest wall or involves the skin of the breast. stage IV breast cancer has spread to distant sites of the body. ...Read more

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Dr. Mike Bowman
962 doctors shared insights

Skin Cancer (Definition)

A condition in which some element of your skin which is one of the most complex organs in the body, degenerates into cancer, with the cancerous (malignant) cells growing ...Read more


Dr. Travis Kidner
2,632 doctors shared insights

Melanoma (Definition)

A type of cancer that develops from pigment-containing ...Read more