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Doctor insights on: Clark Iv Melanoma

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My mum 67 was diagnosed with metastatic caecal adenocarcinoma, aggressive stage 4 cancer.She's on folfox. Life expectancy??

My mum 67 was diagnosed with metastatic caecal adenocarcinoma, aggressive stage 4 cancer.She's on folfox. Life expectancy??

Varies from months/y: The overall survival of stage 4 colon cancer varies from 1 to 3 years. Most patients have at least 2 years if their tumor responds to chemo. If you tumors regresses after chemo, it may even be surgically removable in which case long term survival(even a cure) can be possible. Ask more questions to your treating oncologist. ...Read more

Dr. Mike Bowman
961 doctors shared insights

Skin Cancer (Definition)

A condition in which some element of your skin which is one of the most complex organs in the body, degenerates into cancer, with the cancerous (malignant) cells growing ...Read more


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What constitutes stage 4 melanoma on a superficial mole that has gone malignant?

What constitutes stage 4 melanoma on a superficial mole that has gone malignant?

Metastasis: Stage IV (4) melanoma is the highest stage that a melanoma can reach. It is diagnosed by finding distant spread or metastasis to other parts of the body. Stage is different from clark's levels and breslow levels, although these can impact lower stages. (ajcc cancer staging manual, 7th ed., 2010). ...Read more

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How is stage IV breast cancer different from stage III breast cancer?

How is stage IV breast cancer different from stage III breast cancer?

Location: In stage iii, the cancer still hasn't spread far beyond the breast and nearby lymph nodes. However, in this stage there typically are many lymph nodes involved or the tumor is so large it extends to the chest wall or involves the skin of the breast. stage IV breast cancer has spread to distant sites of the body. ...Read more

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What are metastatic melanoma patients chance sof survival through chemotherapy?

What are metastatic melanoma patients chance sof survival through chemotherapy?

Variable: Depends on how much spread, were e it spread to, and if you are a candidate for chemotherapy. Can be either monthscor multiple years! ...Read more

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Stage 2B IDC breast cancer, her2+/ER/PR+Neoadjuvant taxol, (paclitaxel)A/C,lumpectomy,rads, lymphovascular invasion. What does this mean for prognosis & follow up?

Stage 2B IDC breast cancer, her2+/ER/PR+Neoadjuvant taxol, (paclitaxel)A/C,lumpectomy,rads, lymphovascular invasion. What does this mean for prognosis & follow up?

Prognosis fair: Stage IIb breast cancer is usually palpable at 2-5 cm. and at time of procedure to remove lesion, sentinel nodes are + suggesting axillary dissection and reason for neoadjuvant therapy. Lymphovascular invasion increases chance for recurrence. With Her2+ Herceptin (trastuzumab) with chemo should be used and PET/CAT needed to assure met foci not missed in distal organs. Carful follow up needed. ...Read more

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Is subungual melanoma dangerous?

Is subungual melanoma dangerous?

Yes: If you have an area beneath your nail that is dark, and doesn't resolve like a bruise normally would, then please get it assessed. ...Read more

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Is stage IV metastatic cancer treatable?

Is stage IV metastatic cancer treatable?

Depends: Some cancers are curable with today's chemotherapy even if they have spread extensively. Others (for example, the common lung cancers) may someday be curable when they have reached stage iv, but not today. I've just seen reports of possible cures of stage IV colon and stomach cancers; i'm hopeful. ...Read more

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Diagnosed- malignant melanoma 5/2017 Diagnosed - treated for anal cancer 5/2016. Pet scan done in March '16. If MM has spread, wouldn't PET scan show?

Diagnosed- malignant melanoma 5/2017 Diagnosed - treated for anal cancer 5/2016. Pet scan done in March '16. If MM has spread, wouldn't PET scan show?

PET scan is a good t: PET scan is a good test to detect metastatic cancer. In fact it is our best imaging test to catch metastases early. Yet it has some limitations in that it can not show microscopic tumors/ small # of cells in the body...it only shows tumors that are bigger than half a centimeter (>5 mm). That is why this test has to be repeated every 3 to 4 months when there is a risk for the tumor to come back. ...Read more

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Is chemotherapy required for stage 1A IDC breast cancer, tumor size 1.1 cm, ER & PR positive, HER2 negative, nuclear grade 1. Patient is 42 years old.

Is chemotherapy required for stage 1A IDC breast cancer, tumor size 1.1 cm, ER & PR positive, HER2 negative, nuclear grade 1. Patient is 42 years old.

Borderline call!: Your breast tumor is quite small, so it has >90% odds that it can be safely treated with surgery, without any chemotherapy required. You may ask your doctor for treating you with tamoxifen which is a antihormone type of medication, commonly used as the treatment for tumors that are ER positive. Good luck ...Read more

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Treatment option for anaplastic large cell stage 4 - alk negative i received 2 cycle of chop?

Treatment option for anaplastic large cell stage 4 - alk negative

i received 2 cycle of chop?

Very specific: This is a very specific question and can't be answered adequately in 400 characters. You should really ask this question to your treating physician since they will know all the specifics of your particular case. ...Read more

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Is stage IV pancreatic cancer terminal?

Is stage IV pancreatic cancer terminal?

Yes?: As a rule, stage 4 cancer of the pancreas is incurable. As to being terminal, it depends on the definition. If you mean it will kill the patient at some point, the vast majority of the times the answer is yes. If you mean it will kill the patient right away, it depends on the situation. Never say never, though, some patients have surprised me in the past. Sorry if it is about you or a loved one. ...Read more

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Stage IV nsclc squamous - non operable but currently being treated with navelbine (vinorelbine) and cistplatin. The stage is t3n3 m1b - what are the survival stats?

Stage IV nsclc squamous - non operable but currently being treated with navelbine (vinorelbine) and cistplatin. The stage is t3n3 m1b - what are the survival stats?

Not good: While survival is related to the response to the chemotherapy, survival with advanced stage lung cancer is not good. Over half have died by 8 months, and at 5 years fewer than 10% are alive. Individual response varies, and these are statistics...Remember, people are not "numbers." i hope this helps. ...Read more

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Late stage esophageal cancer, has mestastasized across lympth nodes, & into stage 4 liver, getting chemo now, how long can the person hopefully live?

Late stage esophageal cancer, has mestastasized across lympth nodes, & into stage 4 liver, getting chemo now, how long can the person hopefully live?

Undetermined.: One day at a time. Although statistics can inform you what happened to other people with similar problems, ultimately how long a you are expected to live is speculative and unpredictable. Ultimately, if you are alive today, you are alive today. ...Read more

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Why does basal cell carcinoma have better prognosis than malignant melanoma?

Why does basal cell carcinoma have better prognosis than malignant melanoma?

Ability to travel: Basal cell carcinoma usually is limited to the site of disease. While it is possible for basal cell to metastasize it is very rare. In contrast melanoma travels through the lymphatic system and can form tumors in any location of the body. ...Read more

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Metastatis breast cancer stage IV. What are the chances of survival. already gone six sittings of chemo..

Metastatis breast cancer stage IV. What are the chances of survival. already gone six sittings of chemo..

Breast ca stage IV: need more information. where the metastases are. only bone metastases do better than soft tissue metastases. what is the ER an PR , what is the Her2 status..there are many treatments available now. keep fighting, and you will win. ...Read more

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Stage 4 lung cancer no chemo tumor grew & cancer spread, clinical trial only now, on oxygen for sob, blood clots in legs, what is life expectancy?

Stage 4 lung cancer no chemo tumor grew & cancer spread, clinical trial only now, on oxygen for sob, blood clots in legs, what is life expectancy?

Hard to say/depends.: At this stage of lung cancer, the options are limited as is survival. If treatment is done , it's usually chemotherapy and radiation and/or surgery after adjuvant chemotherapy. There are certainly trials out there and i would recommend talking to your doctor before starting any, but the chance for success is likely limited, as the 5 year survival of stage IV is <5%, but it doesn't hurt to try. ...Read more

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Dr. Travis Kidner
2,631 doctors shared insights

Melanoma (Definition)

A type of cancer that develops from pigment-containing ...Read more