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Doctor insights on: Cjd

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Dr. Suzanne Galli
67 doctors shared insights

Cjd (Overview)

Creutzfeld-Jakob disease (CJD) is a condition where brain damage is caused by abnormal proteins called prions. This damage occurs quickly and causes muscle spasticity and abnormal mental function.


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How is cjd transmitted?

How is cjd transmitted?

Various: There are at least 2 forms. Classic and new variant. Classic includes sporatic and familial) sporadic - which it is unknown but usually occurs later in life. Familial- which is passed genetically. Variant- mostly contamination (small percentage- ie contaminated medical instruments or eating contaminated foods). ...Read more

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Dr. Suzanne Galli
67 doctors shared insights

Cjd (Overview)

Creutzfeld-Jakob disease (CJD) is a condition where brain damage is caused by abnormal proteins called prions. This damage occurs quickly and causes muscle spasticity and abnormal mental function.


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What are the symptoms of sporadic cjd?

What are the symptoms of sporadic cjd?

CJD: Creutzfeldt-jakob disease cjd in sporadic cjd, the disease appears even though the person has no known risk factors for the disease. This is by far the most common type of cjd and accounts for at least 85 percent of cases. ...Read more

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When cjd is such a rare disease, why would a doctor declare a cjd diagnosis without a biopsy? Father had seizures, false positive prion test, dementia

What is a diagnosis: There is a difference between a confirmed diagnosis and a clinical diagnosis. Sometimes a clinical diagnosis is made, without confirmation. For many illnesses, there is no confirmatory test. Most people determine CJD with spinal fluid testing, a biopsy, or autopsy. ...Read more

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Why diagnose cjd without a biopsy? Is there a cancer that can cause same symptoms?

Why diagnose cjd without a biopsy? Is there a cancer that can cause same symptoms?

Not sure, and yes: By cjd i assume you mean creutzfeldt- jacob disease. Although brain biopsy is the "gold standard", it is often not used. The findings from eeg, mri, and spinal tap are enough to make a diagnosis in patients with the right symptoms. Yes, lymphoma in the brain, or a cancer elsewhere in the body causing a "paraneoplastic" syndrome, can cause the same symptoms. Ask if these have been ruled out. ...Read more

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If some of us got in contact with a saliva of an infected cjd person, how would you test if you caught it?

If some of us got in contact with a saliva of an infected cjd person, how would you test if you caught it?

You can't... but: Transmission of cjd through saliva is very unlikely & has not been reported. Furthermore spouse or family members of patient with cjd appear to be at no greater risk of the disease than the general population. There is no way to tell if cjd has been transmitted prior to disease onset. Once symptoms occur then can do tests such as mri, lymph node biopsy for vcjd, spinal fluid tests & brain biopsy. ...Read more

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What are standard tests for cjd?

What are standard tests for cjd?

No easy ones: Cdc website provided the following iinformation."the diagnostic tests performed at the npdpsc include a csf 14-3-3 immunoassay, routine histopathologic analysis, immunohistochemistry, and western blot and prion protein gene analyses." in short there are no easy blood tests. ...Read more

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What is the treatment for cjd?

What is the treatment for cjd?

No curative tx: Current treatment for cjd is aimed at alleviating symptoms and making the individual as comfortable as possible. Opiate drugs can help relieve pain if it occurs, and the drugs Clonazepam and sodium valproate may help relieve myoclonus. During later stages of the disease, changing the person’s position frequently can keep him or her comfortable and helps prevent bedsores. Foley cath, ivfluids, supp. ...Read more

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How can I prevent getting cjd?

Rare disease: There are no specific steps to take, other than to avoid exposure to the body fluids of someone with the disease. ...Read more

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What are the risk factors for sporadic cjd?

None known: Only about 200 cases per year in the US. Other than aging, it's hard to pinpoint specific risk factors. Other forms of CJD may be hereditary or transmitted through tissue transplantation or ingesting infected meat ("mad cow disease"). ...Read more

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