Doctor insights on:
Cisplatin Allergy In Children
Platinol-AQ: "Cisplatin is contraindicated in patients with preexisting renal impairment. Cisplatin should not be employed in myelosuppressed patients, or in patients with hearing impairment. Cisplatin is contraindicated in patients with a history of allergic reactions to Cisplatin or other platinum-containing compounds." See; http://www. Drugs. Com/pro/platinol. Html ...Read more
Allergies occur when your immune system is triggered by envirionmental factors it should ignore--for example, pollen in the air, or dander on a cat or dog--and creates cells to fight against them. An allergic reaction typically causes itching, congestion, or drainage, and ...Read more
Maybe: Cisplatin - like any other chemotherapy drug has potential side effects. The most common is nausea but you can take anti nausea medication. It may cause hair loss and decrease in white blood cell counts. Kidney function should be monitored and IV fluids given. Some long term effects is neuropathy (numbness fingers) and hearing loss but these tend to be due to cumulative dose. ...Read more
Several companies: There are several manufacturers of Cisplatin in the United States and abroad. ...Read more
I shall try: Both drugs are being used in osteosarcoma. Each has its own benefits and side effects. It is a balance beween benefits and risks. Drug combinations areusually used. Age and order of use (1st-round or 2nd) are important factors. Protocols based on national standards are routinely followed. Thank yu for asking. Consult with your cancer doctors. ...Read more
Talk to your doctor: Cisplatin - like any other chemotherapy drug has potential side effects. The most common is nausea but you can take anti nausea medication. It may cause hair loss and decrease in white blood cell counts. Kidney function should be monitored and IV fluids given. Some long term effects is neuropathy (numbness fingers) and hearing loss but these tend to be due to cumulative dose. ...Read more
Anticancerous: Cis platinum developed after work at GM employed soluble platinum in catalytic converters for their cars. It was found in next lab that cultures of bacteria and fungus used to test preservatives on fabrics were dying. Electron microscopy showed platinum entering nucleus to destroy DNA. When tumors were evaluated with platinum, chemical localized on tumor membrane showing presence of DNA in that location. Drug does not enter tumor nucleus but is active in destroying many malignancies. ...Read more
No: The Friedel–Crafts reactions are a set of reactions developed to attach substituents to an aromatic ring. There are two types of reactions: alkylation reactions and acylation reactions. Both proceed by electrophilic aromatic substitutions. When GM use platinum in catalytic converters they found the metal attaching to DNA in bacterial cell cultures, and then determined it attaches to tumor DNA. ...Read more
No treatment: Is available. If severe, hearing aids may be necessary. ...Read more
Cisplatin: Cisplatin toxicity affects kidneys, nerves, marrow, as well as ototoxicity. ...Read more
Platinol-AQ: See: http://www. Drugs. Com/sfx/cisplatin-side-effects. HtmlGet a more detailed answer ›
Can't say: Apocrine gland cancer is rare in humans, more commonly seen in veterinary oncology. Historically these occur mostly in the underarm, or axilla. Surgery is first-line therapy, with additional treatment decided on a case-by-case basis. There hasn't been a well-defined role for chemotherapy as they typically don't respond well to chemotherapy in general. ...Read more
Yes: 5-fu + Cisplatin is a regimen for metastatic cancers ei: anal, biliary, head & neck, esophageal and gastric to name a few. Although they may be other preferred regimens for these cancers. The oncologist will decide what option would be best. ...Read more
Good drug: Cisplatin and its sister drug carboplatin are one of the most useful drugs currently used for the treatment of Lung Cancer. In fact it is recommended that each patient receive a platinum containing combination as the standard of care for patients with advanced stages of lung cancer. But there are other drugs which are equally good (Paclitaxel, Docetaxel and Gemcitabine) ...Read more
What is the survival rate for a stage four tonsil cancel female 54 good health HPV positive non smoker or drinker on cisplatin, 35 radiation, T2N2bM0?
I had gallbladder removed diagnosed cancer had 3 cycles 6 doses of cisplatin and gemtraz now I have to get a pet scan after 14 days is the gap enough.?
Depends: If you haven't had a previous pet/ct, the scan is most likely to establish a baseline for your therapy response. ...Read more
What are the best antiemetics for cisplatin vomiting. Would phenergan (promethazine) work at all? It's to my knowledge that cisplatin is the most emetogenic chemos.
Prevention: The best treatment for cisplatin induced nausea and vomiting is to prevent in the first place. Before cisplatin is given you should get a lot of fluids for hydration, then Dexamethasone, 5HT3 antagonist such as Zofran and NK1 antagonist such as aprepitant. Together this combination with prevent nausea and vomiting. If still sick Compazine, (prochlorperazine) Zofran, etc can help as needed. Remember hydration! ...Read more
My dad will be given cisplatin for squamos carcinoma cell of a mass removed from neck. Is this medicine strong on him? Pet scan clear of mestatsis.
Dose is tailored: Platinum-based medication in treatment of squamous cell cancers after surgery, and often in addition to radiation is the drug of choice. Depending on your dad's kidney function, and overall status, dose of the medication can be adjusted. Sister drug to cisplatin is carboplatin and sometimes used. Erbitux is a new alternative, different side effects, not as effective. ...Read more
Why it is important to establish chloride diuresis prior to cisplatin therapy? How does it prevent renal toxicity?
Toxic on kidneys: The Cisplatin is toxic on the kidneys, and when the kidneys concentrate Cisplatin in the urine, it has a much worse effect. Forcing the kidneys to produce large amounts of urine flushes the Cisplatin through faster and even more important, reduces the concentration in the kidney, which dramatically reduces the toxic effects. ...Read more