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Doctor insights on: Cisplatin Allergy In Children

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Who should not use Platinol-AQ?

Who should not use Platinol-AQ?

Platinol-AQ: "Cisplatin is contraindicated in patients with preexisting renal impairment. Cisplatin should not be employed in myelosuppressed patients, or in patients with hearing impairment. Cisplatin is contraindicated in patients with a history of allergic reactions to Cisplatin or other platinum-containing compounds." See; http://www. Drugs. Com/pro/platinol. Html ...Read more

Dr. John Chiu
2,630 Doctors shared insights

Allergies (Definition)

Allergies occur when your immune system is triggered by envirionmental factors it should ignore--for example, pollen in the air, or dander on a cat or dog--and creates cells to fight against them. An allergic reaction typically causes itching, congestion, or drainage, and ...Read more


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Any bad effects with the chemo drug cisplatin?

Any bad effects with the chemo drug cisplatin?

Maybe: Cisplatin - like any other chemotherapy drug has potential side effects. The most common is nausea but you can take anti nausea medication. It may cause hair loss and decrease in white blood cell counts. Kidney function should be monitored and IV fluids given. Some long term effects is neuropathy (numbness fingers) and hearing loss but these tend to be due to cumulative dose. ...Read more

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Which company makes the chemotherapy agent cisplatin?

Which company makes the chemotherapy agent cisplatin?

Several companies: There are several manufacturers of Cisplatin in the United States and abroad. ...Read more

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Has anyone had any experiance using cisplatin or doxorubicin for osteosarcoma?

Has anyone had any experiance using cisplatin or doxorubicin for osteosarcoma?

I shall try: Both drugs are being used in osteosarcoma. Each has its own benefits and side effects. It is a balance beween benefits and risks. Drug combinations areusually used. Age and order of use (1st-round or 2nd) are important factors. Protocols based on national standards are routinely followed. Thank yu for asking. Consult with your cancer doctors. ...Read more

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Cisplatin needed. What can I expect?

Cisplatin needed. What can I expect?

Talk to your doctor: Cisplatin - like any other chemotherapy drug has potential side effects. The most common is nausea but you can take anti nausea medication. It may cause hair loss and decrease in white blood cell counts. Kidney function should be monitored and IV fluids given. Some long term effects is neuropathy (numbness fingers) and hearing loss but these tend to be due to cumulative dose. ...Read more

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What can you tell me about cisplatin (platinol)?

What can you tell me about cisplatin (platinol)?

Anticancerous: Cis platinum developed after work at GM employed soluble platinum in catalytic converters for their cars. It was found in next lab that cultures of bacteria and fungus used to test preservatives on fabrics were dying. Electron microscopy showed platinum entering nucleus to destroy DNA. When tumors were evaluated with platinum, chemical localized on tumor membrane showing presence of DNA in that location. Drug does not enter tumor nucleus but is active in destroying many malignancies. ...Read more

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How well do 5-FU and cisplatin work for chemotherapy?

Well: 5fu (fluorouracil) and Cisplatin are older chemotherapy agents but have significant roles in the treatment of a wide variety of tumor types even to this day. ...Read more

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Is it possible for cisplatin to carry out alkylating reactions?

Is it possible for cisplatin to carry out alkylating reactions?

No: The Friedel–Crafts reactions are a set of reactions developed to attach substituents to an aromatic ring. There are two types of reactions: alkylation reactions and acylation reactions. Both proceed by electrophilic aromatic substitutions. When GM use platinum in catalytic converters they found the metal attaching to DNA in bacterial cell cultures, and then determined it attaches to tumor DNA. ...Read more

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What to do about hearing loss from cisplatin (ototoxicity)?

What to do about hearing loss from cisplatin (ototoxicity)?

No treatment: Is available. If severe, hearing aids may be necessary. ...Read more

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Is it possible to have hearing loss from cisplatin (ototoxicity)?

Is it possible to have hearing loss from cisplatin (ototoxicity)?

Cisplatin: Cisplatin toxicity affects kidneys, nerves, marrow, as well as ototoxicity. ...Read more

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Do etoposide and cisplatin cause alopecia?

Do etoposide and cisplatin cause alopecia?

Yes: Yes, the regimen will give you alopecia. ...Read more

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Can I change my cisplatin dosage to prevent hearing loss and tennitus?

Can I change my cisplatin dosage to prevent hearing loss and tennitus?

Consult your doctor: Please consult your oncologist about Cisplatin dosage - it appears that you do not have hearing loss yet, you just want to prevent it. ...Read more

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Could carboplatin or cisplatin be used for apocrine gland cancer?

Could carboplatin or cisplatin be used for apocrine gland cancer?

Can't say: Apocrine gland cancer is rare in humans, more commonly seen in veterinary oncology. Historically these occur mostly in the underarm, or axilla. Surgery is first-line therapy, with additional treatment decided on a case-by-case basis. There hasn't been a well-defined role for chemotherapy as they typically don't respond well to chemotherapy in general. ...Read more

Platinol Aq (Definition)

Platinol-AQ is an aklylating agent which is a ...Read more


Dr. Didier Portilla
1,270 Doctors shared insights

Cisplatin (Definition)

Cisplatin is an aklylating agent which is a ...Read more