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Doctor insights on: Circumscribed Scleroderma Localized Type

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Dr. Mary Ellen Luchetti
12 doctors shared insights

Circumscribed Scleroderma (Definition)

Circumscribed scleroderma refers to localized scleroderma ("hard skin"). The body produces excess collagen which produces hardened skin. This can range from a small area of abnormal skin to a disfiguring skin lesion. Even though internal organs are not affected, the hard skin can attach itself to underlying muscle ...Read more


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Skin biopsy result: superficial to mid dermal perivascular lymphocytic infilitrate with focal basal vacuolar changes.does thismean allergic vasculitis?

Skin biopsy result: superficial to mid dermal perivascular lymphocytic infilitrate with focal basal vacuolar changes.does thismean allergic vasculitis?

No: There is no involvement of the blood vessels themselves- thus not vasculitis by definition. This is a very common skin biopsy finding which has no diagnostic meaning other than ruling out a more serious condition. ...Read more

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What sort of disease is circumscribed scleroderma?

What sort of disease is circumscribed scleroderma?

Morphea: Limited scleroderma is called morphea and it is a inflammatory thickening of the skin which is thought to be a reaction to an infection. Early treatment with Minocycline can cause it to burn out leaving discoloration. Fractionated laser can be used on post morphea lesion to i prove color and texture. ...Read more

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What other conditions could 'focal dermal sclerosis' with telangiectasia on a skin biopsy indicate besides scleroderma?

What other conditions could 'focal dermal sclerosis' with telangiectasia on a skin biopsy indicate besides scleroderma?

Depends on clincial: This depends on your clinical status. It could be scleroderma but may not and may be something else. You need an evaluation ...Read more

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What does all this mean..Heterogeneous glandular tissue w mild increased vascularity suggestive of thyroiditis/no focal lesion identified?

What does all this mean..Heterogeneous glandular tissue w mild increased vascularity suggestive of thyroiditis/no focal lesion identified?

Goiter/FNA: If this is your fna/fine needle aspirate result, then your doc will likely recommend medication and monitoring for your thyroid disease. ...Read more

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Myxofibrosarcoma presenting in the skin: clinicopathological features and differential diagnosis with cutaneous myxoid neoplasms.?

Myxofibrosarcoma presenting in the skin: clinicopathological features and differential diagnosis with cutaneous myxoid neoplasms.?

Fairly common: The differential diagnosis will be made by the pathology team. My teacher hector battifora was among the world's most distinguished sarcoma pathologists but said he would never sign one out without another pathologist. The low nuclear grade ones rarely metastasize / kill, but all are prone to annoying local recurrences. Good luck, glad it's this relatively tame (still dangerous) cancer. ...Read more

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Vacuolar interface dermatitis, tight superficl perivascular & periadnexial lymphocytic infiltrate, mild incr. In dermal mucin. No fungus.-rash biopsy.?

Vacuolar interface dermatitis, tight superficl perivascular & periadnexial lymphocytic infiltrate, mild incr. In dermal mucin. No fungus.-rash biopsy.?

Varied possibilities: These findings suggest several possible entities.Based on this description of biopsy findings diagnoses including connective tissue disease such as lupus erythematosus may be considered, as well as a drug reaction. However, the only way to accurately make a diagnosis is to correlate the biopsy findings with the clinical presentation and other symptoms a patient may be having. ...Read more

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What is morphoea localised scleroderma?

What is morphoea localised scleroderma?

Limited disease : Morphea or localized scleroderma is scleroderma limited to isolated areas of skin that have hardened. This occurs as a result of excessice collagen deposits in the skin. In morphea there is generally no associated systemic (internal organ) involvement. ...Read more

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Lichen simplex chronicus pathology was done in 2008 saying;biopsy of skin on chin show hyperkeratosis without fungal infestation, spongiotic changes of the epidermis and a superficial perivascular chronic inflammatory cell infiltrate composed of primari

Lichen simplex chronicus pathology was done in 2008 saying;biopsy of  skin on chin show hyperkeratosis without fungal infestation, spongiotic changes of the epidermis and a superficial perivascular chronic inflammatory  cell infiltrate composed of primari

This : This is very challenging without a clinical examination. This could be lichen simplex chronicus, prurigo nodularis, or other possibilities. Certainly i would get it looked at to be sure so i would recommend you see a dermatologist to further evaluate the area. There are many treatment options to helps these conditions. I hope that helps! ...Read more

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Is Palmar fibrosis a autoimmune disease or Mixed connective tissue disease?

Is Palmar fibrosis a autoimmune disease or Mixed connective tissue disease?

No: It's neither. It's an overgrowth of fibrous tissue that's poorly understood. Sometimes an injection can break it, or surgery's an option. Best wishes. ...Read more

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What is a "connective tissue disease"? Had punch biopsy on rash, suggestive of early connective tissue disease. What is "connective tissue?"

What is a "connective tissue disease"? Had punch biopsy on rash, suggestive of early connective tissue disease. What is "connective tissue?"

Connective tissue: This is a constellation of disease affecting the supporting tissue throughout the body. It involves fat, cartilage,bone.there are different types with names such as Eleros Danlos , Marfans syndrome, Osteogensis imperfecta, they are all a result of gene dysfunction.ie are inheritable disorders. Most are fairly uncommon. The treatment varies depending on the specific areas involved ...Read more

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What is lichenoid muscositis with perivasculitis, ulcerated?

What is lichenoid muscositis with perivasculitis, ulcerated?

Mucosal rash: This is inflammation of the mucous membranes that hugs underside of epidermis=lichenoid. Perivasculitis=inflammation around blood vessels. In mouth, can be lichen planus, lichenoid drug or allergic contact reaction, autoimmune diseases & others. Even canker sores. Direct immunofluorescence biopsy to tell which. In vulva, can also be lichen sclerosus. Some have risk of mouth cancer. Get diagnosis. ...Read more

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Attenuation of hep parenchyma. Diffuse capsular enhancement and focal capsular retraction on liver ct. No focal lesions. Could sle serositis cause ?

Attenuation of hep parenchyma. Diffuse capsular enhancement and focal capsular retraction on liver ct.  No focal lesions.  Could sle serositis cause ?

Possibly, but: Possibly, but I am unfamiliar with such a liver effect. Perhaps fibrosis from an associated disease, such as retroperitioneal fibrosis? ...Read more

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Is chronic diffuse sensorimotor peripheral neuropathy with predominant external & secondary demyelinative changes a long-term disability?

Is chronic diffuse sensorimotor peripheral neuropathy with predominant external & secondary demyelinative changes a long-term disability?

It can be: Sensorimotor peripheral neuropathies have many types and various causes. Some of them can be disabling, even long term in some cases. A thorough search will have to include blood tests and urine tests. In some cases spinal tab (lumbar puncture) can be necessary. In delineating the diagnosis. ...Read more

Dr. Liawaty Ho Dr. Ho
4 doctors agreed:
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Is systemic lupus erythematosus a kind of cancer?

Dr. Liawaty Ho Dr. Ho
4 doctors agreed:
Is systemic lupus erythematosus a kind of cancer?

No : It is an autoimmune disorder that can affect multiple organs. It is not cancer. ...Read more

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How bad is a focal area suggestiv of central fibrosis within liver. Mild centrilobular cholestasis and attached fibroadiposed tissue with fat necrosis?

How bad is a focal area suggestiv of central fibrosis within liver. Mild centrilobular cholestasis and attached fibroadiposed tissue with fat necrosis?

Depends: It is impossible to evaluate these findings without knowing the clinical setting and the results of other tests of liver function. Certainly this does not make me suspect liver cancer. If you have questions about this ultrasound finding, I would ask your doctor or your gastroenterologist. Good luck. ...Read more

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Does any one out there know about morphea scleroderma?

Does any one out there know about morphea scleroderma?

YES SEE BELOW: Morphea is a medical term for localized scleroderma. The disease involves isolated patches of hardened skin - there generally is no internal organ involvement. ...Read more

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What are the tests for circumscribed scleroderma?

What are the tests for circumscribed scleroderma?

Non-specific: A biopsy sometimes can be done. A general examination will see if you have any health problems that need to be assessed. There are no specific tests for circumscribed scleroderma which is also called morphea. ...Read more

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What sort of disease is circumscribed scleroderma?

Morphea: Limited scleroderma is called morphea and it is a inflammatory thickening of the skin which is thought to be a reaction to an infection. Early treatment with Minocycline can cause it to burn out leaving discoloration. Fractionated laser can be used on post morphea lesion to i prove color and texture. ...Read more

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Are there natural ways to treat circumscribed scleroderma?

Exercise: It is a localized disease and the only complication is if effects movement of a body part. If it is on an extremity do exercise and range of motion. A moisturizer will help to soften the skin. ...Read more

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What is the definition or description of: Circumscribed scleroderma?

Localized: Circumscribed scleroderma refers to localized scleroderma ("hard skin"). The body produces excess collagen which produces hardened skin. This can range from a small area of abnormal skin to a disfiguring skin lesion. Even though internal organs are not affected, the hard skin can attach itself to underlying muscle or affect joint motion. ...Read more

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Funny how a diagnosis doesn't mean much till you have it. What is circumscribed scleroderma?

Funny how a diagnosis doesn't mean much till you have it. What is circumscribed scleroderma?

Morphea: Complex localized condition, skin biopsy can be useful. There are some suggested treatment if condition severe enough. ...Read more

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What are the most common symptoms of circumscribed scleroderma? Do I need to have all of them to really have it?

What are the most common symptoms of circumscribed scleroderma? Do I need to have all of them to really have it?

Skin changes: This type of morphea (localized scleroderma) is usually diagnosed simply by the appearance of the skin lesions. A biopsy is not usually needed. There are typically no systemic symptoms. ...Read more

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I don't believe in exposing children to unnecessary treatment. Do I really need to treat circumscribed scleroderma?

No: Treatment is not essential however treatment will cause area to possible resolve quicker and decrease scarring and possible color change. Topical medications are only partially effective but do not have side effects. Oral medications effect is variable. ...Read more

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I try to avoid toxic drugs and treatments. What can I try before I go for traditional medical care for circumscribed scleroderma?

NOT AS SEVERE: Scleroderma is a fascinating disease and has 3 main types, diffuse, limited and localized also known as morphea. Diffuse scleroderma is the most severe. Circumscribed scleroderma or morphea tends to mean a localized area of thickened skin. This tends to be less severe with few compications of other organs which is typical of diffuse scleroderma. Treament is limited. ...Read more

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What is morphoea localised scleroderma?

Limited disease : Morphea or localized scleroderma is scleroderma limited to isolated areas of skin that have hardened. This occurs as a result of excessice collagen deposits in the skin. In morphea there is generally no associated systemic (internal organ) involvement. ...Read more

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Could a chronic wound (localized scleroderma) on dorsal aspect of foot lead to tendonitis?

Could a chronic wound (localized scleroderma) on dorsal aspect of foot lead to tendonitis?

Yes: The thickening of the skin, poor circulation and chronic ulceration occasionally see on the dorsum (top) of the foot can lead to tendonitis of the superficial tendons. ...Read more

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How do people with scleroderma look?

How do people with scleroderma look?

Large range: There are numerous manifestations of scleroderma but the main feature is usually hard skin. This may be thickened hard skin in patches or around just a few fingers +/or toes or around the mouth. Others may have greater involvement of arms, legs causing difficulty moving joints. Worst are disfigurement of face and widespread tight skin over chest, abdomen. ...Read more

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Anyone know anything about scleroderma?

Anyone know anything about scleroderma?

Autoimmune disease : Scleroderma literally means, "hard skin" which is a prominent feature. It is an autoimmune disease that results from cells making excess collagen which hardens and tightens the skin and blood vessels and sometimes internal organs. The severity can vary greatly from person to person. Fortunately, it is a rare disease. A rheumatologist is the best doctor to evaluate and treat this disease. ...Read more

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How does scleroderma progress over time?

How does scleroderma  progress over time?

Depends on type: Some forms of localized scleroderma which affect only the skin do not progress and can even improve. Other forms such as progressive systemic sclerosis can (slowly or quickly) progress to involve the blood vessels and internal organs. It is important to be diagnosed early to anticipate and treat any progressive involvement, especially involvement of the kidneys. ...Read more

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How common is scleroderma, and is their a cause or a cure?

How common is scleroderma, and is their a cause or a cure?

See details: Scleroderma is very uncommon with an incidence of about 19 new cases per 1 million people per year. The cause is unknown and there are no cures. ...Read more

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Dr. Pierre Moeser
184 doctors shared insights

Scleroderma (Definition)

An autoimmune disease in which there is excessive thickening of the connective tissues. This can cause skin tightening, rash, difficulty swallowing, and in severe cases can affect the ...Read more


Dermatosclerosis (Definition)

Dermatosclerosis = scleroderma = autoimmune disease affecting connective tissue & blood vessels. It causes skin to thicken asymmetrically due to deposits of fibrous connective ...Read more